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The map label for this gene is spxA

Identifier: 15675209

GI number: 15675209

Start: 1030599

End: 1031003

Strand: Reverse

Name: spxA

Synonym: SPy_1249

Alternate gene names: 15675209

Gene position: 1031003-1030599 (Counterclockwise)

Preceding gene: 15675210

Following gene: 15675208

Centisome position: 55.66

GC content: 34.57

Gene sequence:

>405_bases
ATGGTTACCTTATTTTTATCACCTAGCTGTACCAGTTGTCGTAAAGCAAGGGCATGGTTAGTAAAACACGAAGTTGACTT
TCAAGAGCATAATATTATTACAAGTCCATTAAGCCGTGATGAATTAATGTCAATCCTCTCTTTTACAGAGAATGGAACGG
AGGATATTATTTCAACACGTTCAAAGGTTTTTCAAAAACTTGATATTGATGTAGAAGAGCTTTCAATTTCAGATTTAATT
GATTTAATTGCTAAAAATCCAAGTCTTCTTCGTCGCCCTATTATCATGGATCAAAAACGCATGCAAATTGGTTTTAATGA
AGATGAAATTAGAGCGTTTTTATCGAGAGATTATCGCAAGCAAGAACTACGTCAAGCAACGATAAAAGCAGAAATTGAGG
GGTGA

Upstream 100 bases:

>100_bases
ATTGGAATATGATAAACGAACAGCATTAAATTGGAAAAAAGATAGCAAATTATCTTAAATTTTTGTATAATAAGGTAAGT
AAATTTGATAGAGGAAAAAT

Downstream 100 bases:

>100_bases
TATGTCAGGTAATTATTATTATCCACTTGACTTAAGTTGGAGCACTGAAGAAATATCCTCAGTGCTTCATTTTTTGAATA
AAGTGGAATTAGCATATGAA

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLI
DLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRKQELRQATIKAEIEG

Sequences:

>Translated_134_residues
MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLI
DLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRKQELRQATIKAEIEG
>Mature_134_residues
MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLI
DLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRKQELRQATIKAEIEG

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX_STRP1 (P60381)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269383.1
- RefSeq:   YP_282322.1
- ProteinModelPortal:   P60381
- SMR:   P60381
- EnsemblBacteria:   EBSTRT00000000985
- EnsemblBacteria:   EBSTRT00000028578
- GeneID:   3571934
- GeneID:   901349
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1249
- KEGG:   spz:M5005_Spy_0959
- GeneTree:   EBGT00050000027616
- HOGENOM:   HBG734370
- OMA:   FTERNIF
- ProtClustDB:   PRK01655
- BioCyc:   SPYO160490:SPY1249-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0959-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 15528; Mature: 15528

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTR
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRK
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCHHCCCHHHHCCCCHHHHHHHHHHHHHH
QELRQATIKAEIEG
HHHHHHHHHHCCCC
>Mature Secondary Structure
MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMSILSFTENGTEDIISTR
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQIGFNEDEIRAFLSRDYRK
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCHHCCCHHHHCCCCHHHHHHHHHHHHHH
QELRQATIKAEIEG
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296