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The map label for this gene is mreA [H]

Identifier: 15675210

GI number: 15675210

Start: 1031046

End: 1031978

Strand: Reverse

Name: mreA [H]

Synonym: SPy_1250

Alternate gene names: 15675210

Gene position: 1031978-1031046 (Counterclockwise)

Preceding gene: 15675211

Following gene: 15675209

Centisome position: 55.71

GC content: 34.08

Gene sequence:

>933_bases
ATGGAAATTGAATATATCAAAGATTATCGTGATATTAACCAAGAAGATGATACAGTCTTGATATTGGGATATTTTGATGG
ATTACACCGTGGTCATAAAGCCTTATTTGACAAAGCAAGAGAGGTTGCAAATAAAGAAGGGTTAAAAGTAGTCGTTTTTA
CGTTTACAGAGTCTCCGAAATTGGCTTTTTCGCGTTTTTCTCCTGAGTTATTGCTTCATATTACTTATCCAAAGAAGCGT
TATGAAAAATTTGCCGATTACGGTGTAAATAAATTATATTTGGTTGATTTTACTTCTAAATTCTCTAAGGTCTCATCTGA
TCATTTTATAACTCATTATATTAAAAACCTGAAAGCAAAGCATATTGTTGTCGGTTTTGACTATAAGTTTGGGCATAATC
GTACAGATAGTGATTATTTAACCAGAAATTTTGAAGGACAAGTTTATACCATTGAGGAAATAAAAGAAGATCATCGAAAA
ATTTCTGCTACATGGATAAGGAAGCTTATTCAAGAAGGTAATGTAGTTAAAGCAAACCACTTGTTAGGCTATGACTTATC
GACAAGGGGAAGAGTCGTTCACGGGGATGCGCGTGGCCGTACTATTGGTTTCCCAACAGCCAATCTAGCTCCAATTGACA
ACACATACTTACCAGCTGATGGAGTCTATGTTACAAATGTTATTGTTGCTAATAAAATCTATCGCTCTATGACGAGTTTA
GGTAAAAATGTGACATTTGGGGGGAAAGAGTTGCGTCTAGAAGTTAACATTTTTGACTTTGACGAAGAGATCTATGGAGA
AATTATTGAGATTGTTTGGTTAGATAAGATTCGAGACATGGAAAAATTCGAGGGAATCGAAGATTTGACTGATAGATTGG
AATATGATAAACGAACAGCATTAAATTGGAAAAAAGATAGCAAATTATCTTAA

Upstream 100 bases:

>100_bases
CATGGCGAAAAAGTAATTGCTATTTTAGAAAAAAGAGATCAAGAATACAAACCCAAAAAAGTTCTTATTTAAATAGTTTG
AGTAAGTAGAATGGATAATT

Downstream 100 bases:

>100_bases
ATTTTTGTATAATAAGGTAAGTAAATTTGATAGAGGAAAAATATGGTTACCTTATTTTTATCACCTAGCTGTACCAGTTG
TCGTAAAGCAAGGGCATGGT

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS

Sequences:

>Translated_310_residues
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS
>Mature_310_residues
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=307, Percent_Identity=32.5732899022801, Blast_Score=165, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 36047; Mature: 36047

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPK
CCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
LAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAK
HHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHCCCCHHHHHHHHCCCCC
HIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRKISATWIRKLIQEGNVVKANH
EEEEEEEEECCCCCCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECE
LLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSL
EEEECCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
LNWKKDSKLS
CCCCCCCCCC
>Mature Secondary Structure
MEIEYIKDYRDINQEDDTVLILGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPK
CCCHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
LAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAK
HHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHCCCCHHHHHHHHCCCCC
HIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRKISATWIRKLIQEGNVVKANH
EEEEEEEEECCCCCCCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECE
LLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLPADGVYVTNVIVANKIYRSMTSL
EEEECCCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
LNWKKDSKLS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9454067; 9108293; 9384377 [H]