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The map label for this gene is dltR [H]

Identifier: 15674899

GI number: 15674899

Start: 721374

End: 722042

Strand: Direct

Name: dltR [H]

Synonym: SPy_0874

Alternate gene names: 15674899

Gene position: 721374-722042 (Clockwise)

Preceding gene: 15674898

Following gene: 15674900

Centisome position: 38.94

GC content: 34.68

Gene sequence:

>669_bases
ATGAAAATTTTGTTAGCTGAAGACGAATGGCAGATGTCTAATGTTTTGACAACTGCCATGACTCATCAAGGTTATGACGT
TGATGTGGTTTTTAACGGTCAAGAGGCAATTGATAAAGCCAAAGACAATGCATATGATATTATGATTTTAGATATCATGA
TGCCGATTAAGTCTGGCATTGAGGCTTTAAAGGAGATTCGCGCTTCAGGAAATTGCTCACATATTATTATGCTGACGGCT
ATGGCAGAAATTAATGACCGTGTTACCGGACTAGATGCGGGAGCTGATGATTATCTGACTAAACCTTTCTCATTAAAAGA
ACTTTTAGCTAGATTAAGGTCGATGGAAAGACGAGTAGAAAGTTTTACTCCTCAGGTATTACAATTTGCTGGTGTCACAT
TAAATATTAATGAGCAAGAATTGAGTGCCGGTAATGCTATACGATTAGCTTCTAAAGAAGGTAAATTAATGGCCTTTTTA
ATGTTAAATCAAGGAAAGTACTTGGATACTAAAACGCTTTACCAACATGTTTGGTCAGACCAAGAAGATTATGATACTTC
TATTGTTTGGGTTTATATTTCTTATCTTCGTCAAAAATTATTAGCTATTCAAGCAAATGTCATTATTGCAGGTGATAAAG
ATACTAGCTATTGTTTATTAGAAAAATAG

Upstream 100 bases:

>100_bases
CAAGAGAGTTAAAGCGTTGTGCAGACGAGTTGGCATCTTGTGATGTTACCATGCAAACCATTCGTCAATTGATTCAAGAA
ACGACGGAGGAAGAGTAACC

Downstream 100 bases:

>100_bases
GAGGTGACATGTTTAATCGTATCCGCATTCGTTTTATCATGATTGCTTCTATTGCCATTTTTATTATTTTAAGTTCAATT
GTTGGTATTATTAACACGGC

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTA
MAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK

Sequences:

>Translated_222_residues
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTA
MAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
>Mature_222_residues
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTA
MAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=202, Percent_Identity=36.1386138613861, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1789402, Length=201, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=201, Percent_Identity=35.3233830845771, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=208, Percent_Identity=34.1346153846154, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=30, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=201, Percent_Identity=34.8258706467662, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790552, Length=201, Percent_Identity=32.8358208955224, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.1818181818182, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789809, Length=147, Percent_Identity=34.6938775510204, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788394, Length=208, Percent_Identity=29.3269230769231, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=34.2857142857143, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=30.1435406698565, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=39.2523364485981, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790863, Length=179, Percent_Identity=32.9608938547486, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1790299, Length=179, Percent_Identity=25.1396648044693, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790437, Length=127, Percent_Identity=28.3464566929134, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788713, Length=125, Percent_Identity=32.8, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25055; Mature: 25055

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGI
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCEEEEEEHHHHHHHHHH
EALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVE
HHHHHHHCCCCCCEEEEEEEHHHHCCCEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
SFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLNQGKYLDTKTLYQHVWSD
HCCHHHHHHCCCEEEECHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCC
QEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
CCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGI
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCCEEEEEEHHHHHHHHHH
EALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVE
HHHHHHHCCCCCCEEEEEEEHHHHCCCEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHHH
SFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLNQGKYLDTKTLYQHVWSD
HCCHHHHHHCCCEEEECHHHHCCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCC
QEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
CCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]