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The map label for this gene is ywaC [H]

Identifier: 15674898

GI number: 15674898

Start: 720721

End: 721371

Strand: Direct

Name: ywaC [H]

Synonym: SPy_0873

Alternate gene names: 15674898

Gene position: 720721-721371 (Clockwise)

Preceding gene: 15674896

Following gene: 15674899

Centisome position: 38.91

GC content: 35.33

Gene sequence:

>651_bases
ATGAAAGAAAGACTAGAACATTATTCTACCAGCTCTATATATAGCGGATTTGAAGTGTACTTGCCGTTGGTACTACAGAC
AATAACAGATGTGATTATTGCTGAGAATATCAAAAGCAAAAAAGAAACGGGGTTTAAACTATACGAACACTTTACATCCC
GTATTAAATCGGAAGCTTCGATGATTGAAAAATGTCAACGCAAACAGCTTCCTCTAACAAGCAAATCTGCGTTAAAAATC
ATTAAAGATAGTATCGGTATTCGCATTATTTGTGGTTTTATTGATGATATTTATCGGATGGTAGACTTGCTCAAAAGCAT
TCCTGGTATGTCAGTTAACACTGAAAAAGATTATATTTTAAATGCCAAGCCTAATGGCTATAGATCATATCATCTCATTT
TGGAATTAGAAACACATTTTCCAGATATTTTAGGGGAAAAAAAAGGATGTTATTTTATAGAAGTGCAGTTGCGAACCATT
GCTCAAGACTCTTGGGCTAGCTTGGAACATCAAATGAAGTACAAACATCAAGTTGCTAATGCAGAAATGATTACAAGAGA
GTTAAAGCGTTGTGCAGACGAGTTGGCATCTTGTGATGTTACCATGCAAACCATTCGTCAATTGATTCAAGAAACGACGG
AGGAAGAGTAA

Upstream 100 bases:

>100_bases
AAACGATACAGATCATTTGAAGTTATATAGTTAGAAATAAAGATAACCGATCATTGCAGAGATTTAAGCATTTGTTGAGA
AAATTTGTTATAATAAGCGT

Downstream 100 bases:

>100_bases
CCATGAAAATTTTGTTAGCTGAAGACGAATGGCAGATGTCTAATGTTTTGACAACTGCCATGACTCATCAAGGTTATGAC
GTTGATGTGGTTTTTAACGG

Product: GTP pyrophosphokinase

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2 [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGFKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKI
IKDSIGIRIICGFIDDIYRMVDLLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE

Sequences:

>Translated_216_residues
MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGFKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKI
IKDSIGIRIICGFIDDIYRMVDLLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE
>Mature_216_residues
MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGFKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKI
IKDSIGIRIICGFIDDIYRMVDLLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 25008; Mature: 25008

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGFKLYEHFTSRIKSEAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLLKSIPGMSVNTEKDYIL
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
NAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQDSWASLEHQMKYKHQVAN
ECCCCCCEEEEEEEEECHHCHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AEMITRELKRCADELASCDVTMQTIRQLIQETTEEE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGFKLYEHFTSRIKSEAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLLKSIPGMSVNTEKDYIL
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
NAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQDSWASLEHQMKYKHQVAN
ECCCCCCEEEEEEEEECHHCHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AEMITRELKRCADELASCDVTMQTIRQLIQETTEEE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]