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The map label for this gene is trxB [C]

Identifier: 15674883

GI number: 15674883

Start: 701256

End: 702248

Strand: Direct

Name: trxB [C]

Synonym: SPy_0850

Alternate gene names: 15674883

Gene position: 701256-702248 (Clockwise)

Preceding gene: 15674882

Following gene: 15674884

Centisome position: 37.86

GC content: 37.26

Gene sequence:

>993_bases
GTGAAAGATAAAGCATATGATATTACGATTATTGGTGGTGGTCCAATAGGTTTATTTGCAGCCTTTTATGCAGGTCTTAG
GGGCGTAACAGTAAAGATTATTGAGAGTTTGTCAGAACTTGGTGGACAGCCTGCCATTCTTTATCCTGAGAAAATGATTT
ATGATATTCCAGCTTATCCATCTTTAACAGGTGTTGAGTTGACAGAAAATTTAATAAAACAATTGAGCCGTTTTGAAGAT
CGTACAACCATTTGTTTAAAAGAAGAAGTATTAACCTTTGACAAGGTTAAAGGTGGTTTTTCGATTAGGACTAATAAGGC
AGAGCATTTTTCAAAAGCCATTATCATTGCTTGTGGAAATGGCGCTTTTGCACCAAGAACTTTAGGGTTAGAAAGTGAGG
AAAACTTTGCTGATCATAACCTTTTTTATAATGTTCACCAGTTGGACCAGTTTGCGGGACAAAAAGTTGTGATTTGTGGT
GGTGGAGATTCAGCAGTTGATTGGGCTTTGGCTTTAGAAGATATTGCTGAGAGTGTGACGGTTGTGCACCGTCGTGATGC
TTTCAGAGCACATGAACACAGTGTGGAATTATTGAAAGCATCAACGGTCAACCTCTTAACACCTTATGTGCCAAAAGCAT
TGAAAGGAATTGGAAACCTGGCTGAAAAATTAGTTATTCAAAAAGTGAAAGAAGATGAAGTGTTAGAACTTGAATTGGAC
AGTCTTATTGTTAGTTTTGGTTTTTCAACTTCTAATAAGAATTTGAAAAATTGGAATCTCGACTATAAGCGTTCAAGTAT
TACTGTTTCACCACTTTTTCAAACAAGTCAAGAAGGTATTTTTGCCATTGGTGATGCAGCCGCTTATAATGGGAAAGTGG
ATTTGATTGCTACTGGTTTTGGCGAAGCACCAACAGCAGTTAATCAGGCCATTAACTATATTTATCCAGATCGAGATAAC
CGTGTGGTGCATTCAACCTCTTTAATTGACTAA

Upstream 100 bases:

>100_bases
ATTTAAGGCGGCCAGATTTACTTGAACATTACAATTTTTCCGAGGAAGAGCGCAAGCTATTGGATAAGATTAAAGAAGCA
TTGGATCAAGGAGAAGATTA

Downstream 100 bases:

>100_bases
GGGAGTCGGAAGTTTCAAGAGCAGTAGCAACAGCTAATATTCAGTTTGTCAGGAGAGGACAAATGGTTTTTACCTAAGTC
TTCGTGACAAGTTTTATACT

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: FNR; Fd-NADP+ reductase

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID

Sequences:

>Translated_330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID
>Mature_330_residues
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFED
RTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDN
RVVHSTSLID

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Escherichia coli, GI1787114, Length=298, Percent_Identity=29.8657718120805, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321898, Length=296, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FENR_STRP1 (Q9A0B5)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269057.1
- RefSeq:   YP_282020.1
- ProteinModelPortal:   Q9A0B5
- EnsemblBacteria:   EBSTRT00000000363
- EnsemblBacteria:   EBSTRT00000027405
- GeneID:   3572247
- GeneID:   901014
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0850
- KEGG:   spz:M5005_Spy_0657
- GeneTree:   EBGT00050000027206
- HOGENOM:   HBG669726
- OMA:   QIAITSI
- ProtClustDB:   CLSK698502
- BioCyc:   SPYO160490:SPY0850-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0657-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 36119; Mature: 36119

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: BINDING 35-35 BINDING 43-43 BINDING 48-48 BINDING 90-90 BINDING 123-123 BINDING 285-285 BINDING 326-326

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYP
CCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHEEECCCCC
SLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGN
CCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEECCCHHHCCEEEEEEECC
GAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVT
CCCCCEEECCCCCCCCCCCHHEEEHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
HHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGF
HEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCCCEEEEEEECC
GEAPTAVNQAINYIYPDRDNRVVHSTSLID
CCCCHHHHHHHHEECCCCCCEEEECCCCCC
>Mature Secondary Structure
MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYP
CCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCHHHEEECCCCC
SLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGN
CCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEECCCHHHCCEEEEEEECC
GAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVT
CCCCCEEECCCCCCCCCCCHHEEEHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELD
HHHHHHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
SLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGF
HEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCCCEEEEEEECC
GEAPTAVNQAINYIYPDRDNRVVHSTSLID
CCCCHHHHHHHHEECCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296