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The map label for this gene is atpA

Identifier: 15674806

GI number: 15674806

Start: 616645

End: 618153

Strand: Direct

Name: atpA

Synonym: SPy_0758

Alternate gene names: 15674806

Gene position: 616645-618153 (Clockwise)

Preceding gene: 15674805

Following gene: 15674807

Centisome position: 33.29

GC content: 42.28

Gene sequence:

>1509_bases
TTGGCAATTAATGCACAAGAAATTAGCGCTTTAATTAAAAAGCAAATTGAGAACTTCCAGCCAAATTTCGATGTCACAGA
AACTGGGATCGTTACCTATATTGGTGACGGTATTGCACGTGCCCGTGGATTAGATAATGCCATGAGTGGTGAACTTCTTG
AATTTGAAAATGGTGCCTACGGGATGGCTCAAAACCTTGAGTCAAATGATGTGGGTATTATTATTCTTGGTGATTTTTCA
GCAATCCGTGAAGGAGATGTGGTTAAGCGCACCGGTAAAATCATGGAAGTACCAGTTGGTGAAGCTCTCATTGGACGTGT
GGTAAACCCACTTGGACAACCAGTTGATGGCTTGGGAGATATTGAAACAACTGGCTTTAGACCAGTAGAAACGCCAGCTC
CTGGTGTTATGCAGCGTAAATCCGTTTCTGAACCCTTACAAACTGGATTAAAAGCAATTGATGCTTTGGTTCCAATTGGT
CGTGGGCAACGTGAGTTGATTATCGGAGACCGTCAAACAGGAAAAACATCCGTAGCTATTGATGCGATTTTGAACCAAAA
AGGTCAAGACATGATTTGTATCTATGTGGCTATTGGTCAAAAAGAATCAACCGTTCGTACACAAGTTGAAACCCTTCGCC
GTTACGGTGCCTTGGATTATACTATTGTTGTGACAGCGTCAGCCTCACAACCATCACCATTGCTCTTTATCGCTCCTTAT
GCGGGTGTTGCCATGGCTGAAGAATTTATGTACCAAGGCAAGCATGTCTTGATTGTCTATGATGATTTATCAAAACAAGC
GGTGGCTTATCGTGAATTGTCTCTCTTGCTTCGTCGTCCACCAGGTCGTGAGGCTTACCCAGGGGATGTTTTCTACTTGC
ATAGCCGTCTTTTGGAACGCTCTGCAAAAGTTTCTGATGACTTAGGTGGAGGTTCTATCACAGCTCTACCATTTATCGAA
ACACAGGCCGGAGATATCTCTGCATATATTGCGACTAACGTTATTTCGATTACAGACGGACAAATCTTCTTGCAAGAGAA
CCTCTTTAATTCAGGAATTCGTCCAGCGATTGATGCAGGATCATCTGTCTCACGTGTAGGTGGTTCCGCTCAAATTAAAG
CGATGAAAAAGGTTGCTGGTACTCTTCGTTTGGATTTGGCTTCCTATCGTGAATTAGAAGCCTTTACCCAATTTGGTTCG
GACCTTGATGCTGCAACACAAGCAAAACTTAATCGTGGTCGCCGTACGGTTGAAATCTTGAAGCAACCATTGCATAAACC
GTTACCTGTTGAAAAGCAAGTCGTTATTCTTTATGCCCTTACTCATGGTTTCTTAGATGATGTTCCTGTAGATGATATTT
TGGCTTTTGAAGAAGCTCTTTACGACTACTTTGACGTTCATTACAATGATTTATTTGAAACTATCCGTACCACAAAAGAC
CTTCCTGAAGAAGCTGCCCTTGATGCCGCTATTAAAGCGTTTAAAGAACACTCAAACTTTAAGTCATAG

Upstream 100 bases:

>100_bases
AGGATTTATTATCAGCGTCAATAATAAAGTAATTGATACCAGTATTCGTCGTCAATTGCAAGCATTTAAAATGAATTTAA
AATAGAAAGTGGTGTGACTT

Downstream 100 bases:

>100_bases
AGGGAGGATACTAGTATGGCAGGCTCTCTAAGTGAAATTAAAGCTAAAATTATTTCAACTGAGAAAACAAGTAAAATCAC
TAGTGCCATGCGTATGGTTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFS
AIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGS
DLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKD
LPEEAALDAAIKAFKEHSNFKS

Sequences:

>Translated_502_residues
MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFS
AIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGS
DLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKD
LPEEAALDAAIKAFKEHSNFKS
>Mature_501_residues
AINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSA
IREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYA
GVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIET
QAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSD
LDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDL
PEEAALDAAIKAFKEHSNFKS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=494, Percent_Identity=57.8947368421053, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI4757810, Length=494, Percent_Identity=57.8947368421053, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=29.2358803986711, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=29.2358803986711, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI32189394, Length=455, Percent_Identity=25.7142857142857, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=52.4366471734893, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=34.9264705882353, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790170, Length=384, Percent_Identity=26.3020833333333, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=481, Percent_Identity=58.4199584199584, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=481, Percent_Identity=58.4199584199584, Blast_Score=561, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=481, Percent_Identity=54.0540540540541, Blast_Score=503, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=362, Percent_Identity=27.9005524861878, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=28.7128712871287, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=429, Percent_Identity=23.5431235431235, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=38.6666666666667, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=498, Percent_Identity=56.0240963855422, Blast_Score=558, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=28.8524590163934, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=409, Percent_Identity=24.4498777506112, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658560, Length=494, Percent_Identity=57.6923076923077, Blast_Score=556, Evalue=1e-158,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.9036544850498, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.9036544850498, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.9036544850498, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28574560, Length=409, Percent_Identity=25.4278728606357, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638766, Length=409, Percent_Identity=24.9388753056235, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583988, Length=259, Percent_Identity=27.4131274131274, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583986, Length=259, Percent_Identity=27.4131274131274, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583984, Length=259, Percent_Identity=27.4131274131274, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_STRP1 (Q9A0I9)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268980.1
- RefSeq:   YP_281942.1
- ProteinModelPortal:   Q9A0I9
- SMR:   Q9A0I9
- EnsemblBacteria:   EBSTRT00000001524
- EnsemblBacteria:   EBSTRT00000027471
- GeneID:   3572325
- GeneID:   900937
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0758
- KEGG:   spz:M5005_Spy_0579
- GeneTree:   EBGT00050000027468
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   SPYO160490:SPY0758-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0579-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54686; Mature: 54555

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAY
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCHHCCCEEEECCCCC
GMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGD
HHHCCCCCCCEEEEEEECCHHHCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAG
HHHCCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEECCEEEEECCHHCCCCCCHHCCC
SSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEIL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKD
HHHCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPEEAALDAAIKAFKEHSNFKS
CCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHCCCCCHHCCCEEEECCCCC
GMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGD
HHHCCCCCCCEEEEEEECCHHHCCCCHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
IETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPY
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAG
HHHCCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEECCEEEEECCHHCCCCCCHHCCC
SSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEIL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKD
HHHCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPEEAALDAAIKAFKEHSNFKS
CCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296