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The map label for this gene is atpH

Identifier: 15674805

GI number: 15674805

Start: 616093

End: 616629

Strand: Direct

Name: atpH

Synonym: SPy_0757

Alternate gene names: 15674805

Gene position: 616093-616629 (Clockwise)

Preceding gene: 15674804

Following gene: 15674806

Centisome position: 33.26

GC content: 34.64

Gene sequence:

>537_bases
ATGACCAAAAAAGAACAGGCTCTTATCGAGCAATATGCAAAAAGCCTTGTTGAGGTGGCGAGTGAACATCATTCTCTTGA
TGCCTTACAAGCTGATGTGCTTGCGATTTTAGAGACGTTTGTAACAACTAATCTTGATCAAAGTCTATCAAGTCAAGCTG
TTCCGCATGCTGAAAAAATAAAATTGCTAACCTTATTAAAGGGAAATAATTCTGTTTATATGAATAATTTCTTGAATCTC
ATTTTACAAAACGAACGTGAAGCTTATTTGTATCAAATGCTTCAGGCTGTTTTAAATGAAATTGCAATAGTTTCAAATCA
GTATGATGTGACTGTTACCTCATCACTACCTTTGACTGAGGAGCAAAAAAGCCGTGTTCGAGCAGTTGTTGCAAAGAAAT
TTGCTGTAACAGCGGGTCGTTTAATTGAAAAAGTAGATCCTTCGCTTATTGGAGGATTTATTATCAGCGTCAATAATAAA
GTAATTGATACCAGTATTCGTCGTCAATTGCAAGCATTTAAAATGAATTTAAAATAG

Upstream 100 bases:

>100_bases
TAACGGTTCTTTTAGCGGAAAAAATTATGGGAGCCAATCTTGATAAGACGGCGCAAAGCCAGCTTATTGACAGTTATCTT
GATGACTTAGGAGAAGCTTA

Downstream 100 bases:

>100_bases
AAAGTGGTGTGACTTTTGGCAATTAATGCACAAGAAATTAGCGCTTTAATTAAAAAGCAAATTGAGAACTTCCAGCCAAA
TTTCGATGTCACAGAAACTG

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSQAVPHAEKIKLLTLLKGNNSVYMNNFLNL
ILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
VIDTSIRRQLQAFKMNLK

Sequences:

>Translated_178_residues
MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSQAVPHAEKIKLLTLLKGNNSVYMNNFLNL
ILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
VIDTSIRRQLQAFKMNLK
>Mature_177_residues
TKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSQAVPHAEKIKLLTLLKGNNSVYMNNFLNLI
LQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKV
IDTSIRRQLQAFKMNLK

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_STRP1 (Q9A0J0)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268979.1
- RefSeq:   YP_281941.1
- ProteinModelPortal:   Q9A0J0
- SMR:   Q9A0J0
- EnsemblBacteria:   EBSTRT00000001518
- EnsemblBacteria:   EBSTRT00000027911
- GeneID:   3572324
- GeneID:   900936
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0757
- KEGG:   spz:M5005_Spy_0578
- GeneTree:   EBGT00050000027976
- HOGENOM:   HBG697205
- OMA:   EVSEMIQ
- ProtClustDB:   PRK05758
- BioCyc:   SPYO160490:SPY0757-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0578-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19902; Mature: 19771

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSQAVPHAEKI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
KLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTE
EEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCH
EQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKVIDTSIRRQLQAFKMNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSQAVPHAEKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHH
KLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTE
EEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCH
EQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKVIDTSIRRQLQAFKMNLK
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296