The gene/protein map for NC_002737 is currently unavailable.
Definition Streptococcus pyogenes M1 GAS chromosome, complete genome.
Accession NC_002737
Length 1,852,441

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The map label for this gene is yrrO [H]

Identifier: 15674677

GI number: 15674677

Start: 475960

End: 477246

Strand: Direct

Name: yrrO [H]

Synonym: SPy_0591

Alternate gene names: 15674677

Gene position: 475960-477246 (Clockwise)

Preceding gene: 15674676

Following gene: 15674678

Centisome position: 25.69

GC content: 45.22

Gene sequence:

>1287_bases
ATGTCACATATGAAAAAACGTCCCGAGGTCTTATCACCTGCTGGAACACTTGAAAAATTAAAAGTTGCGATTGACTATGG
CGCAGATGCTGTTTTTGTTGGAGGGCAGGCCTATGGCCTAAGAAGCCGCGCTGGTAACTTCTCTATGGAAGAATTGCAAG
AAGGCATTGATTATGCACATGCGCGTGGAGCTAAGGTCTATGTTGCTGCTAACATGGTTACCCACGAAGGGAACGAAATT
GGTGCGGGCGAGTGGTTTCGTCAACTGCGTGATATGGGGCTTGATGCGGTCATTGTTTCAGATCCAGCCTTGATTGTTAT
TTGTTCAACAGAAGCCCCAGGTTTGGAAATTCATTTGTCAACGCAAGCTTCATCTACCAATTACGAGACCTTTGAATTTT
GGAAAGCCATGGGCTTGACCCGAGTTGTTTTAGCTCGCGAGGTTAATATGGCCGAGTTAGCAGAAATCCGCAAGCGGACA
GATGTGGAAATTGAAGCCTTTGTCCATGGAGCCATGTGTATCTCTTATTCAGGCCGCTGTGTTTTGTCAAACCACATGAG
TCACCGTGATGCCAACAGGGGCGGCTGCTCACAGTCTTGCCGCTGGAAGTATGATTTGTATGACATGCCATTTGGAGGAG
AGCGCCGCTCCTTAAAAGGGGAAATTCCAGAAGACTATTCTATGTCCTCTGTTGACATGTGTATGATTGACCATATTCCT
GACCTGATTGAAAATGGGGTTGATAGCTTAAAAATTGAAGGCCGAATGAAATCTATCCACTACGTCTCAACCGTAACCAA
CTGTTACAAGGCGGCTGTAGGTGCTTACATGGAAAGCCCAGAAGCTTTTTATGCTATCAAAGAGGAATTGATTGACGAGT
TGTGGAAGGTTGCCCAGCGCGAGTTGGCTACAGGTTTTTACTATGGTATCCCAACTGAAAATGAACAATTATTTGGTGCT
CGCCGCAAAATTCCACAATATAAATTTGTCGGAGAAGTAGTTGCCTTTGACTCAGCTAGCATGACAGCGACCATTCGTCA
GCGTAATGTCATCATGGAAGGCGATCGGATTGAATGTTATGGACCAGGTTTCCGTCATTTTGAAACGGTTGTTAAGGACT
TACATGATGCGGATGGCCAAAAGATTGACCGTGCCCCAAATCCAATGGAACTCTTAACCATCTCTTTACCGAGAGAAGTT
AAGCCAGGGGATATGATTAGGGCTTGCAAGGAAGGTCTGGTTAACCTCTATCAAAAAGATGGCACCAGTAAAACTGTTAG
AACATAG

Upstream 100 bases:

>100_bases
CGTTAAATAAGTAATCCTTGTCTTGAGTGAGTGGGCAAGACAGGGTTATGACACCATTACACAGGTAATCTACCTATCTT
GAAAATAGAAAGAATATCAC

Downstream 100 bases:

>100_bases
TAACAAGAAATACTAGAGGCCCTCTTTTTCCAAATGGTATACGACCATAGTTGGGAAAAGAGAGCCTGTTTTTTTTGAAA
ATTGGATATCACAATAGCTT

Product: putative protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEI
GAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVGAYMESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGA
RRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREV
KPGDMIRACKEGLVNLYQKDGTSKTVRT

Sequences:

>Translated_428_residues
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEI
GAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVGAYMESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGA
RRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREV
KPGDMIRACKEGLVNLYQKDGTSKTVRT
>Mature_427_residues
SHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIG
AGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTD
VEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIPD
LIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVGAYMESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGAR
RKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVK
PGDMIRACKEGLVNLYQKDGTSKTVRT

Specific function: Unknown

COG id: COG0826

COG function: function code O; Collagenase and related proteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U32 family [H]

Homologues:

Organism=Escherichia coli, GI1788397, Length=437, Percent_Identity=33.4096109839817, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI87081910, Length=280, Percent_Identity=37.1428571428571, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789548, Length=309, Percent_Identity=31.3915857605178, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001539 [H]

Pfam domain/function: PF01136 Peptidase_U32 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 47855; Mature: 47724

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS01276 PEPTIDASE_U32

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAH
CCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLS
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEEEEEE
TQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTDVEIEAFVHGAMCISYSGRC
CCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCEEEHHEEEEEEEECCCCE
VLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
EEECCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVGAYMESPEAFYAIKEELIDELWKVAQR
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ELATGFYYGIPTENEQLFGARRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECY
HHHCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEECCCEEEECCEEEEE
GPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVKPGDMIRACKEGLVNLYQKD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GTSKTVRT
CCCCCCCC
>Mature Secondary Structure 
SHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGIDYAH
CCCCCCCCCCCCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
ARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDPALIVICSTEAPGLEIHLS
CCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCEEEEEE
TQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRTDVEIEAFVHGAMCISYSGRC
CCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCEEEHHEEEEEEEECCCCE
VLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSLKGEIPEDYSMSSVDMCMIDHIP
EEECCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
DLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVGAYMESPEAFYAIKEELIDELWKVAQR
HHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ELATGFYYGIPTENEQLFGARRKIPQYKFVGEVVAFDSASMTATIRQRNVIMEGDRIECY
HHHCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHEECCCCCEEEEECCCEEEECCEEEEE
GPGFRHFETVVKDLHDADGQKIDRAPNPMELLTISLPREVKPGDMIRACKEGLVNLYQKD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
GTSKTVRT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]