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The map label for this gene is lgt

Identifier: 15674672

GI number: 15674672

Start: 472671

End: 473450

Strand: Direct

Name: lgt

Synonym: SPy_0585

Alternate gene names: 15674672

Gene position: 472671-473450 (Clockwise)

Preceding gene: 161378152

Following gene: 15674673

Centisome position: 25.52

GC content: 36.41

Gene sequence:

>780_bases
ATGATCAATCCCATTGCCTTAAAATGTGGTCCACTAGCCATCCACTGGTATGCTCTATGTATCTTGTCAGGACTTGTTTT
GGCGGTTTACTTAGCATCAAAAGAAGCACCCAAAAAAGGAATATCATCTGATGCTATTTTCGATTTTATTCTGATTGCTT
TTCCACTTGCTATTGTTGGTGCAAGAATTTACTATGTTATTTTTGAATGGTCTTATTATGTCAAGCATTTAGATGAAATC
ATAGCCATTTGGAATGGCGGTATTGCTATTTATGGCGGTCTCATTACAGGAGCTCTTGTACTTTTGGCTTACTGTTATAA
CAAGGTGCTCAATCCCATTCATTTTTTAGATATTGCCGCACCAAGTGTCATGGTCGCTCAAGCTATCGGTCGCTGGGGAA
ATTTTATCAACCAAGAAGCCTATGGTAAAGCTGTGAGCCAGTTAAATTACTTACCAAGCTTTATTCAAAAGCAAATGTTT
ATAGAGGGAAGTTACCGCATTCCGACCTTTCTCTATGAATCACTTTGGAATCTTTTGGGCTTTGTCATTATTATGATGTG
GCGTCGTAAGCCAAAAAGTCTATTAGATGGAGAAATCTTTGCATTTTACTTAATTTGGTATGGTAGTGGAAGACTAGTCA
TTGAAGGTATGCGAACAGATAGTCTTATGTTTTTAGGTATTCGCATCTCCCAATATGTGTCTGCCTTATTAATTATTATT
GGCTTAATCTTTGTTATAAAAAGACGTCGTCAAAAAGGAATTTCTTATTATCAAGAATAA

Upstream 100 bases:

>100_bases
CCGCTGCGATGAATCATCGGGCTAAAGAAATGGGCTTTGATGCTACAAAAACTTTTGAAGATCGTTTAACTCAACTAATC
ACCAAAAATGAGGTGAGTCA

Downstream 100 bases:

>100_bases
GGATAGAAAAAGGAGAAACTTATGGACTTAGTTGGAATCTCACTGATGATTATTGCACTCGCATTTGTTGCTTTGGTGAT
TTTCTTGATTATTGTATTAA

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE

Sequences:

>Translated_259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE
>Mature_259_residues
MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEI
IAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIII
GLIFVIKRRRQKGISYYQE

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=283, Percent_Identity=27.208480565371, Blast_Score=100, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_STRP1 (P60965)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268846.1
- RefSeq:   YP_281848.1
- EnsemblBacteria:   EBSTRT00000001369
- EnsemblBacteria:   EBSTRT00000028702
- GeneID:   3572423
- GeneID:   900798
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0585
- KEGG:   spz:M5005_Spy_0485
- GeneTree:   EBGT00050000027948
- HOGENOM:   HBG450278
- OMA:   CARAYYV
- ProtClustDB:   PRK00052
- BioCyc:   SPYO160490:SPY0585-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0485-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 29421; Mature: 29421

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xaf54f0c)-; HASH(0xca90ca4)-; HASH(0xbd0c430)-; HASH(0xbad3f68)-; HASH(0xb10dd9c)-; HASH(0xbe7a6f0)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296