Click here to switch to the map view.

The map label for this gene is ptsK [H]

Identifier: 161378152

GI number: 161378152

Start: 471682

End: 472674

Strand: Direct

Name: ptsK [H]

Synonym: SPy_0584

Alternate gene names: 161378152

Gene position: 471682-472674 (Clockwise)

Preceding gene: 15674670

Following gene: 15674672

Centisome position: 25.46

GC content: 39.58

Gene sequence:

>993_bases
ATGAGTATTTGCAAGGGTCTAACGGTCGATTTGTGTTATAATATTGAAAAAGGAGAAATTATGACCGTTACTGTAAAGAT
GCTAGTGCAAAAAGTTAAACTTGATGTGGTTTATGCTACAGATAACTTGCTGTCAAAAGAGATAACAACATCAGATATTT
CACGTCCAGGTCTTGAAATGACTGGTTATTTTGATTATTATGCTCCAGAAAGGTTGCAGCTATTTGGAATGAAAGAGTGG
TCTTATCTTACACAGATGACTTCTCACAACCGTTATTCTGTTTTAAAAGAGATGTTCAAAAAGGACACTCCTGCAGTGGT
TGTCTCTAGAAATTTAGCCATTCCAAAAGAAATGGTTCAAGCTGCAAAAGAAGAAGGTATTTCACTTTTAAGTAGCCGTG
TTTCAACTAGCCGCTTAGCTGGAGAAATGTCTTATTTTCTTGACGCTTCTTTAGCTGAACGTACTAGTGTTCACGGCGTT
TTAATGGATATTTATGGTATGGGGGTTCTTATCCAAGGGGATTCTGGAATTGGTAAAAGTGAGACTGGTTTAGAATTAGT
TAAGCGAGGGCATCGTTTGGTTGCAGATGACCGTGTGGATGTCTATGCCAAAGATGAAGAAACCCTTTGGGGAGAGCCAG
CAGAGATCTTGCGCCACTTGCTTGAAATTCGTGGGGTAGGTATTATTGATGTGATGTCGCTTTATGGAGCTAGTGCTGTG
AAGGACTCATCACAAGTTCAATTGGCCATTTACCTTGAAAACTTTGAGGCTGGTAAAGTTTTTGATCGTCTCGGAAACGG
AAATGAGGAGATAACTTTCTCAGGAGTGAGAATCCCTCGTATTCGTATTCCGGTAAAAACAGGTCGAAATGTTTCAGTGG
TTATTGAAGCCGCTGCGATGAATCATCGGGCTAAAGAAATGGGCTTTGATGCTACAAAAACTTTTGAAGATCGTTTAACT
CAACTAATCACCAAAAATGAGGTGAGTCAATGA

Upstream 100 bases:

>100_bases
ATTGTCTTATTTTTGACTCATATCTCTAAATGATAAAACCTAGTTTTTAATAGAGCTAAGACCATTTTTGGTGTCGTTGT
TCTCATTTAGTAGTGAAAAA

Downstream 100 bases:

>100_bases
TCAATCCCATTGCCTTAAAATGTGGTCCACTAGCCATCCACTGGTATGCTCTATGTATCTTGTCAGGACTTGTTTTGGCG
GTTTACTTAGCATCAAAAGA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSICKGLTVDLCYNIEKGEIMTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEW
SYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGV
LMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAV
KDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLT
QLITKNEVSQ

Sequences:

>Translated_330_residues
MSICKGLTVDLCYNIEKGEIMTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEW
SYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGV
LMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAV
KDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLT
QLITKNEVSQ
>Mature_329_residues
SICKGLTVDLCYNIEKGEIMTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEWS
YLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVL
MDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAVK
DSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLTQ
LITKNEVSQ

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 36782; Mature: 36651

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSICKGLTVDLCYNIEKGEIMTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEM
CCCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHEEEEEECCHHHHHHCCHHHCCCCCCCE
TGYFDYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQ
EEEECCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAV
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHC
KDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAM
CCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEECEEECEEEEECCCCCCEEEEEEEHHH
NHRAKEMGFDATKTFEDRLTQLITKNEVSQ
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SICKGLTVDLCYNIEKGEIMTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEM
CCCCCCEEEEEEECCCCCEEEHHHHHHHHHHHEEEEEECCHHHHHHCCHHHCCCCCCCE
TGYFDYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQ
EEEECCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAV
HHHHHHHHCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHC
KDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAM
CCCCCEEEEEEEECCCHHHHHHHHCCCCCEEEEECEEECEEEEECCCCCCEEEEEEEHHH
NHRAKEMGFDATKTFEDRLTQLITKNEVSQ
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA