Click here to switch to the map view.

The map label for this gene is oxaA2

Identifier: 15674505

GI number: 15674505

Start: 307083

End: 308006

Strand: Reverse

Name: oxaA2

Synonym: SPy_0351

Alternate gene names: 15674505

Gene position: 308006-307083 (Counterclockwise)

Preceding gene: 15674506

Following gene: 15674490

Centisome position: 16.63

GC content: 39.94

Gene sequence:

>924_bases
TTGAAACTAACATTAAATCGCATCCTCTTTTCAGGACTAGCACTGTCAATTCTACTCACCTTGACAGGCTGTGTGGGAAG
AGACGCTCACGGAAATCCCAAAGGTATGATTTGGGAATTTCTTGGAAAACCCATGTCATACTTTATCGATTACTTTGCAA
ACAATGCTGGACTAGGTTATGGACTGGCTATCATCATCGTAACCATTATTGTTAGAACACTTATCTTACCACTAGGTCTA
TATCAATCTTGGAAAGCAAGTTATCAATCTGAGAAAATGGCCTTCTTGAAACCTGTTTTTGAACCAATCAACAAACGTAT
CAAACAGGCAAATAGTCAGGAAGAAAAAATGGCTGCCCAAACAGAATTAATGGCTGCTCAGCGTGCTCATGGGATTAACC
CTCTTGGAGGTATTGGATGTCTACCTCTTCTCATCCAGATGCCATTCTTTTCTGCCATGTATTTTGCCGCTCAATACACT
AAAGGAGTATCAACAAGCACCTTTATGGGTATTGATCTTGGTAGCCGTAGTTTAGTGTTAACAGCAATTATCGCTGCTCT
TTACTTCTTCCAATCATGGTTATCAATGATGGCCGTTTCAGAAGAACAACGTGAGCAAATGAAGACGATGATGTACACCA
TGCCTATCATGATGATCTTCATGTCCTTCTCACTCCCTGCTGGTGTTGGTCTTTACTGGCTAGTTGGTGGTTTCTTTAGT
ATTATTCAACAGTTAATCACAACCTACCTCTTAAAACCTCGATTGCATAAGCAAATTAAAGAAGAATACGCTAAAAACCC
GCCTAAAGCATACCAATCAACTTCTTCTCGTAAGGACGTTACGCCTTCACAAAACATGGAACAGGCTAACTTGCCTAAAA
AAATAAAATCCAATCGTAATGCTGGAAAACAGCGAAAGCGTTAA

Upstream 100 bases:

>100_bases
CTTTCAAATAGGCAAGTAAAAATCGGCCTTCAGAACTATTGTGAATTTCTGAAAAAAACTGTAAAATAGATAAGTATATT
AAAATTAAAGGATAAACACA

Downstream 100 bases:

>100_bases
GAAAGACAAAAAACCTAGCACAATTATGAACTGCACTCCAAAAGTTAGACAAAAAACGATATGCCCCCTTTTACTGGACT
CATCTAGTGAAAGGGGACAT

Product: OxaA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGL
YQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFS
IIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR

Sequences:

>Translated_307_residues
MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGL
YQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFS
IIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR
>Mature_307_residues
MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGL
YQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFS
IIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=234, Percent_Identity=31.1965811965812, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA2_STRP1 (Q9A1C3)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268679.1
- RefSeq:   YP_281659.1
- EnsemblBacteria:   EBSTRT00000000964
- EnsemblBacteria:   EBSTRT00000027867
- GeneID:   3572624
- GeneID:   900627
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0351
- KEGG:   spz:M5005_Spy_0295
- GeneTree:   EBGT00050000027293
- HOGENOM:   HBG560622
- OMA:   TTYVLKP
- ProtClustDB:   PRK02463
- BioCyc:   SPYO160490:SPY0351-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0295-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 34506; Mature: 34506

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb2ca078)-; HASH(0xc3f2cd4)-; HASH(0xca49d1c)-; HASH(0xc3fba2c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCH
>Mature Secondary Structure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CCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296