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The map label for this gene is metI [H]

Identifier: 15674485

GI number: 15674485

Start: 282704

End: 283366

Strand: Direct

Name: metI [H]

Synonym: SPy_0321

Alternate gene names: 15674485

Gene position: 282704-283366 (Clockwise)

Preceding gene: 15674484

Following gene: 15674487

Centisome position: 15.26

GC content: 37.41

Gene sequence:

>663_bases
ATGTTTATGAACTCGGATGGTCATGGAGATGCAGGTTGGGGCTTAGCGATTTGGAATACTTTATACATGACCATTGTGCC
TTTTATTGTTGGGGGGGCTATTGGTCTCTTATTAGGCTTGTTATTAGTTTTAACAGGACCGGACGGTGTTATTGAAAACA
AAACGATTTGTTGGGTTATTGATAAAGTTACCTCTATTTTTAGAGCCATTCCTTTTGTTATTTTGATTGCTATTTTAGCT
AGCTTTACCTATTTGCTTTTAAGAACAACTTTAGGAGCAACAGCGGCCTTGGTACCTTTAACCTTTGCGACTTTTCCTTT
TTATGCCCGTCAGGTCCAAGTTGTTTTTTCAGAATTAGACAAGGGTGTTATTGAAGCAGCACAAGCTTCAGGTGCTACTT
TCTGGGATATTGTCAAAGTGTATCTCAGTGAAGGTTTACCAGATCTTATTCGTGTTTCTACAGTCACCTTAATTTCTTTA
GTTGGGGAAACTGCCATGGCAGGAGCTATCGGTGCTGGAGGATTAGGAAATGTAGCGATTTCTTATGGTTATAATCGTTT
TAACAATGATGTGACTTGGGTAGCGACTATTATTATTCTTTTAATTATTTTTGCTATCCAATTTATTGGTGATAGCTTGA
CTAGAAGGTTTAGTCATAAATAA

Upstream 100 bases:

>100_bases
ATTCTTGCGGCTGAGAAAGCCTTGCATGAAGCTGGTGTTGATGTTAGTATTTTAAAGAGAGGAGCCTAGATGTCACAGTT
AATTCAAACTTATTTGCCAA

Downstream 100 bases:

>100_bases
ACGAAACAACACCCTAAGTAAAAACTTAGGGTGTTGTTGTTTAGATGATGTCATTAGCTTTTCTTCGTTTTACTTAGTAT
AAGCCCTATTAAAAAACCAA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MFMNSDGHGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILA
SFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISL
VGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK

Sequences:

>Translated_220_residues
MFMNSDGHGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILA
SFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISL
VGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
>Mature_220_residues
MFMNSDGHGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILA
SFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISL
VGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=205, Percent_Identity=42.4390243902439, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23664; Mature: 23664

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMNSDGHGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DKVTSIFRAIPFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISLVGETAMAGAIGAGGLGNVAI
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
SYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
HHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFMNSDGHGDAGWGLAIWNTLYMTIVPFIVGGAIGLLLGLLLVLTGPDGVIENKTICWVI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
DKVTSIFRAIPFVILIAILASFTYLLLRTTLGATAALVPLTFATFPFYARQVQVVFSELD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGVIEAAQASGATFWDIVKVYLSEGLPDLIRVSTVTLISLVGETAMAGAIGAGGLGNVAI
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
SYGYNRFNNDVTWVATIIILLIIFAIQFIGDSLTRRFSHK
HHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]