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The map label for this gene is sstT

Identifier: 15674487

GI number: 15674487

Start: 285024

End: 286238

Strand: Direct

Name: sstT

Synonym: SPy_0324

Alternate gene names: 15674487

Gene position: 285024-286238 (Clockwise)

Preceding gene: 15674485

Following gene: 15674491

Centisome position: 15.39

GC content: 37.45

Gene sequence:

>1215_bases
ATGAAAAAAATATATGATTTATGGGTTAGGGTTAGTCTAATCAAAAAAATAGGTATCGGTGTTGTAATAGGAGTCATGTT
GGGCATTTTGGCTCCTGATCTTACAGGTTTTAGTATTTTAGGAAAGTTATTTGTTGGTGGTTTAAAGGCTATCGCACCTT
TGCTTGTATTTGCTTTGGTTTCCCAAGCTATCTCCCATCAGAAAAAAGGGAAACAGACTAATATGACATTAATCATTGTT
CTGTATTTATTTGGTACCTTTGCGTCAGCTTTAGTAGCAGTACTGACAGCTTATCTATTCCCTTTGACGTTAGTGTTAAA
TACACCTGTAAATACAGAATTATCACCACCTCAAGGTGTTGCTGAAGTTTTTCAGTCACTTCTATTAAAATTAGTGGATA
ATCCGATCAATGCTTTAGCTACTGCCAATTATATTGGTGTGCTATCATGGGCAATTATTTTTGGACTAGCATTAAAGGCT
GCAAGTAAAGAAACAAAGCATCTTATAAAAACAGCGGCAGAAGTTACTTCACAAATAGTTGTTTGGATCATCAATCTGGC
ACCTATTGGGATTATGAGTCTGGTGTTCACTACGATTTCTGAAAACGGTGTTGGAATCTTATCTGATTATGCTTTTTTGA
TACTAGTTTTAGTAGGAACAATGCTTTTTGTCGCCTTAGTGGTTAATCCACTTATTGCGGTTTTGATTACACGACAAAAT
CCTTATCCCCTTGTCTTGAGATGTTTACGTGAGTCAGGTCTTACAGCATTTTTCACACGAAGTTCTGCAGCCAATATTCC
AGTCAATATGCAATTATGCCAAAAAATTGGATTGAGTAAAGATACTTATTCAGTGTCAATTCCACTTGGAGCAACTATTA
ATATGGGTGGGGCAGCAATTACCATCAATGTCCTAACGCTTGCTGCTGTACACACTTTTGGTATTCCTATTGATTTTCTA
ACAGCCCTCTTACTTAGCGTTGTTGCTGCTGTCTCTGCTTGTGGTGCTTCTGGTGTTGCTGGGGGATCGTTGTTACTTAT
TCCTGTAGCATGTAGTTTGTTTGGCATTTCAAATGATCTTGCGATGCAGGTGGTTGGTGTTGGTTTTATTGTTGGTGTTA
TCCAGGATTCTTGTGAGACAGCCTTAAATTCGTCAACCGATGTTCTTTTTACAGCTATTGCTGAAAATGCTTTTTGGAAA
CGTAAAAAAGCATAG

Upstream 100 bases:

>100_bases
TAGCACAAAAAATGGTTAAGATATGTAGCTCATTCGATTTGCCGAATAGATAGAATTATATTATTATAAAAAACATGTAC
CTTTAGTAAGGATGTAACGT

Downstream 100 bases:

>100_bases
CTAGATTTAACATAGTAAAAAACATCCTTGGAAAACGCCAAGGATGTTTTTTTATTATTTAAGATAGCCAAGATAATCAA
ATTTTTCAAAGGTGTGGTCA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIV
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASKETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMLFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA

Sequences:

>Translated_404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIV
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASKETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMLFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA
>Mature_404_residues
MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIV
LYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
ASKETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMLFVALVVNPLIAVLITRQN
PYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFL
TALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWK
RKKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468564, Length=261, Percent_Identity=31.8007662835249, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI223468566, Length=261, Percent_Identity=31.8007662835249, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI5032093, Length=261, Percent_Identity=31.8007662835249, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI21314632, Length=274, Percent_Identity=30.6569343065693, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI169790839, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4827012, Length=268, Percent_Identity=25, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1789473, Length=370, Percent_Identity=60, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1789947, Length=254, Percent_Identity=29.9212598425197, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790514, Length=309, Percent_Identity=24.9190938511327, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71996953, Length=290, Percent_Identity=25.1724137931034, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=267, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=270, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=271, Percent_Identity=26.1992619926199, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983106, Length=285, Percent_Identity=25.6140350877193, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_STRP1 (Q9A1E0)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268661.1
- RefSeq:   YP_281639.1
- ProteinModelPortal:   Q9A1E0
- SMR:   Q9A1E0
- EnsemblBacteria:   EBSTRT00000001629
- EnsemblBacteria:   EBSTRT00000027587
- GeneID:   3572643
- GeneID:   900609
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0324
- KEGG:   spz:M5005_Spy_0275
- GeneTree:   EBGT00050000027349
- HOGENOM:   HBG289387
- OMA:   TAVISHY
- ProtClustDB:   PRK13628
- BioCyc:   SPYO160490:SPY0324-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0275-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 42555; Mature: 42555

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc563f10)-; HASH(0xc8ca3bc)-; HASH(0xafb33c4)-; HASH(0xc87fb94)-; HASH(0xc6f5a9c)-; HASH(0xcc05334)-; HASH(0xb296fb4)-; HASH(0xc87fa98)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296