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The map label for this gene is pgi [H]

Identifier: 15674409

GI number: 15674409

Start: 191686

End: 193035

Strand: Direct

Name: pgi [H]

Synonym: SPy_0215

Alternate gene names: 15674409

Gene position: 191686-193035 (Clockwise)

Preceding gene: 15674408

Following gene: 15674411

Centisome position: 10.35

GC content: 41.26

Gene sequence:

>1350_bases
ATGTCACATATTACATTTGATTATTCAAAAGTCCTCGAGTCATTTGCGGGACAACATGAAATTGATTTTTTACAAGGCCA
AGTAACAGAAGCTGACAAGTTATTGCGTGAAGGAACTGGACCAGGTTCAGATTTCTTGGGCTGGCTTGATCTTCCAGAAA
ACTATGATAAAGATGAATTTGCACGTATCTTGACTGCTGCTGAAAAGATTAAGGCAGACAGCGAAGTTCTTGTGGTGATC
GGTATCGGTGGGTCATACCTTGGTGCCAAAGCAGCGATTGATTTTTTAAATCATCATTTTGCTAACTTGCAAACTGCCAA
AGAGCGCAAAGCCCCACAAATTCTTTACGCTGGAAACTCTATTTCATCTACTTACCTTGCCGATTTAGTTGAATACGTTC
AAGACAAAGAGTTCTCAGTAAACGTGATCTCTAAATCAGGTACAACCACTGAACCAGCTATTGCCTTTCGCGTGTTCAAA
GAACTTTTGGTTAAAAAATATGGCCAAGAAGAAGCTAACAAACGTATCTACGCTACCACAGACAAAGTTAAGGGTGCTGT
TAAGGTAGAAGCTGACGCTAACAACTGGGAAACATTTGTGGTGCCAGATAATGTTGGTGGTCGTTTCTCAGTCTTGACTG
CTGTTGGTTTGCTTCCAATTGCTGCATCAGGTGCAGATATTACTGCTCTTATGGAAGGGGCAAATGCTGCTCGTAAAGAC
CTTTCTTCAGACAAAATCTCTGAAAACATTGCTTACCAATACGCTGCTGTTCGTAATGTGCTTTACCGTAAAGGCTACAT
CACTGAAATCTTGGCTAACTACGAGCCATCTCTTCAGTACTTTGGCGAATGGTGGAAACAATTAGCTGGTGAATCAGAAG
GAAAAGATCAAAAAGGGATTTACCCAACTTCAGCTAACTTCTCAACAGACCTTCACTCACTTGGTCAATTTATCCAAGAA
GGTTACCGTAATCTCTTTGAAACAGTTATTCGTGTTGATAATCCTCGTAAAAATGTTATCATTCCTGAATTAGCAGAAGA
CCTAGATGGACTTGGTTACCTTCAAGGTAAAGACGTTGATTTCGTTAACAAGAAAGCTACAGATGGTGTGCTTCTTGCCC
ACACAGATGGCGGCGTGCCAAACATGTTTGTCACTCTTCCAGCTCAAGACGAGTTTACCCTTGGTTACACTATTTACTTC
TTTGAGCTTGCCATCGCTGTTTCAGGCTACATGAATGCTGTTAACCCATTTGATCAACCAGGTGTTGAAGCTTACAAACG
TAACATGTTTGCGCTTCTTGGAAAACCAGGTTTTGAAGCATTATCAGCAGAGCTTAATGCTCGCCTCTAA

Upstream 100 bases:

>100_bases
CTAGCTTTTTCACAGGTGAAAACCACTAAAAACCATTGAAATATTAGATAGAAAAGGTTATCATACTAATGAAACTTAAA
ATTTTAAGGGAGCGAAACTC

Downstream 100 bases:

>100_bases
TCAACAGATAGTCAAAAAGACTTCTTCCTTGTACAAGAGCTTAAAAGTTAGCCAAGCAATCTAAGAATTGGGGCGGCACT
TCCATCATCGAGTGGATACA

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVI
GIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
LSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE
GYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYF
FELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL

Sequences:

>Translated_449_residues
MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVI
GIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
LSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE
GYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYF
FELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
>Mature_448_residues
SHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVIG
IGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKE
LLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDL
SSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEG
YRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFF
ELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71996703, Length=383, Percent_Identity=25.8485639686684, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996708, Length=383, Percent_Identity=25.8485639686684, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319673, Length=375, Percent_Identity=25.6, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 49453; Mature: 49322

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEF
CCCEECCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHH
ARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
ISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEH
DKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
HHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
LSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
YPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCCCCCCCC
FVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQP
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
GVEAYKRNMFALLGKPGFEALSAELNARL
CHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEF
CCEECCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHH
ARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
ISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEH
DKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKD
HHCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHC
LSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
YPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCCCCCCCC
FVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQP
CCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
GVEAYKRNMFALLGKPGFEALSAELNARL
CHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA