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The map label for this gene is yeeO [H]

Identifier: 15674285

GI number: 15674285

Start: 62219

End: 63511

Strand: Direct

Name: yeeO [H]

Synonym: SPy_0045

Alternate gene names: 15674285

Gene position: 62219-63511 (Clockwise)

Preceding gene: 15674284

Following gene: 15674286

Centisome position: 3.36

GC content: 41.14

Gene sequence:

>1293_bases
ATGATATATAATAATAGAAGAAAAATTTTCTCTTTAGCTCTGCCTTCTATGATAGAAAATATTTTACAGATGTTAATGGG
AATGGTTGATAATTACCTGGTGGCTCAAATTGGACTTGTAGCAGTCTCTGGTGTCTCCATAGCTAACAACATTATCAGTA
TTTATCAGTCCCTCTTTATCGCGCTGGGAGCTGCTGTATCTAGTCTGATTGCTCGAAGTATTGGAGAAAATAATCAGAAC
AAACAATTAAACTATATGGCAGGTGTCTTGCAAGTAACACTCCTCCTTTCGGTCGGCTTAGGGTTGTTATCAGTTGCTGG
ACATCATCAGGTGTTAGAATGGCTAGGAGCTGAAGCTTCTGTAACATTGGTTGGAGGGCAATATCTATCCATTGTCGGCG
GTATGATTGTTAGTCTAGGACTTTTAACTAGCTTAGGAGCTATTGTTCGAGCTCAAGGGTATCCTAAGATTCCTATGCAA
GTGAGCTTATTAATAAACGTACTCAATGCCATTTTTTCTGCCTTGTCTATCTATGTATGGGGATTTGGTCTTCTTGGTGT
TGCTTGGGCGACGGTTTTATCTCGTTTAGTGGGTGTGTTTTTACTTTGTCAGTTTATTCCTATTAAACAGGTTGCGAAAC
GATTGATGAGACCTTTGGACAAAATTATTTTTGATTTATCACTACCTGCTGCTGGTGAACGTTTGATGATGAGAGCAGGA
GATGTCCTAATTATTGGCATTGTTGTTCGCTTTGGGACAACGGCCTTGGCAGGTAATGCTATTGGAGAAACCTTGACTCA
GTTTAATTACATGCCTGGCTTAGCCATGGCAACGGCAACAATTATTCTAGTGGCTAGGCAACTGGGGGGCGGTAAGGTGA
CTGAGATAAGGTATATTATTAGAGAAGCTTTTATTTTATCCACCCTCATGATGCTGGTTATGGGAGCCTTGACCTATCTG
CTAGGTCCTAGTCTCTTGCCGCTATTTACACAGAATACTGATGCTCAAAGGTCTGCCATGATTGTTTTACTTTTTTCTTT
ACTAGGAGCTCCCGCAACGGCAGGCACTTTAGTTTATACAGCCGTCTGGCAGGGTTTGGGAAAAGCAAAGCTTCCTTTCT
ATGCAACAACCATAGGAATGTGGGTGATTCGCATTGGCCTTGGTTATGTGATTGGTGTGGTTTGGCAATATGGACTCATA
GGGGTCTGGATGGCGACAGTGTTAGATAATACCAGTCGGTGGTTTATTCTCTCTAAACACTTTAAAAAGTACCAAGAAAT
TACCTTTCATTAG

Upstream 100 bases:

>100_bases
AGACTTTATGAATTCATTAATGGACCAAAATAACTGAATGAGTCCAGTGACTGTGTTTGAAAAAATCGTTTGATCAAGAA
TTTTTTATTAGGGGACATAA

Downstream 100 bases:

>100_bases
GAAGGTAGTTTTTTTTTGAAAAAAATGCCTAAAAAGCTTGCAATGACTAAATGATTCTGTTATTATATTGTGGTGCTGTA
AAAATACAGCTTTAGCAATG

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYL
LGPSLLPLFTQNTDAQRSAMIVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLI
GVWMATVLDNTSRWFILSKHFKKYQEITFH

Sequences:

>Translated_430_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYL
LGPSLLPLFTQNTDAQRSAMIVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLI
GVWMATVLDNTSRWFILSKHFKKYQEITFH
>Mature_430_residues
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFIALGAAVSSLIARSIGENNQN
KQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQ
VSLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYL
LGPSLLPLFTQNTDAQRSAMIVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLI
GVWMATVLDNTSRWFILSKHFKKYQEITFH

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=427, Percent_Identity=27.1662763466042, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46534; Mature: 46534

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCE
VTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQVSLLINVLNAIFSALSIYVW
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYII
CCHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
REAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDAQRSAMIVLLFSLLGAPATAGTLVYT
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
AVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLIGVWMATVLDNTSRWFILSKH
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
FKKYQEITFH
HHHHHHHCCC
>Mature Secondary Structure
MIYNNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGVSIANNIISIYQSLFI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLLSVAGHHQVLEWLGAEAS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCE
VTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQVSLLINVLNAIFSALSIYVW
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPLDKIIFDLSLPAAGERLMMRAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
DVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMATATIILVARQLGGGKVTEIRYII
CCHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
REAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDAQRSAMIVLLFSLLGAPATAGTLVYT
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
AVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGVVWQYGLIGVWMATVLDNTSRWFILSKH
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
FKKYQEITFH
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]