Click here to switch to the map view.

The map label for this gene is gsiC [H]

Identifier: 13474911

GI number: 13474911

Start: 4765730

End: 4766671

Strand: Direct

Name: gsiC [H]

Synonym: mlr5896

Alternate gene names: 13474911

Gene position: 4765730-4766671 (Clockwise)

Preceding gene: 13474910

Following gene: 13474912

Centisome position: 67.73

GC content: 62.74

Gene sequence:

>942_bases
ATGAGTGCTGTGTTTCGTTTCGCCGGCCCCAAGATCCTGCGTGCCGGCCTGTCGATCCTGGTCGTGGTGACCTTTACATT
CGTGGTGCTGCGGGCCTCTGGAGACCCGGCGCTGCAGATACTCGGTCCCAGCGCCCGCGCCCCGGATCTTGAGGCGTTTC
GCCGGCATTGGGGGCTCGATCAGCCTCTGTATGTGCAATATGTTCGCTATGTCCTGGCGGCACTTCACTGCGATTTCGGG
AATTCCATGCTAGCTGGAAAACCGGCCCTGCAGCTTGTGTTCGAGCGCGCGCCCCTGACATTGGCGCTGATGCTGCCGGC
ACTGGCGCTCACGATGCTGATCGGCATTCCGGTCGGCGCCTACGCCGCCATGCATCGCGACACCTGGGTCGACCGATCGG
TGATGATGGTGACCGTGTTCGGCTTCACCGTGCCAAGCTTCGTGCTCGGGCTATTGCTGATCCTGATCTTTTCCGTGACG
CTCGGCCTGTTCCCGTCCGGCGGCGCGGATCGGCCGGAAAGCTTCGTACTGCCGGTGCTCACCCTTGGTTTGGGCGGGGC
GGCCATTATCGCGCGCTTCACGCGTAGCGCCATGATCGAAGTTCTGTCGCAGCTCTACATCGTGGCGGCCAGCGCCAAGG
GCGTGACGTGGCGGCAGGTGGTTCGCCACCATGCCTTTCCGAATGCGATCATTCCTGTGCTGACGCTGTTCGGCCTGATG
CTCGGCGGCCAGGTCGCGGGCGCCGTACTGGTGGAAAGCGTCTTCGGCTGGCCCGGCATCGGCCAATTGCTGGTGGTTTC
GGTTGCGAACCGTGATCTCGCCGTGGTGCAGGTCATCCTCCTTCTCGTGGCGCTGACCATGACGTCGGCCAACCTGCTGA
TGGACCTGCTTTATGGCGTGTTCGATCCGCGCTTGCGTGGAACAAACTCAGGATCGCAATGA

Upstream 100 bases:

>100_bases
CACGCTGTCCACTTGCGCGCGATGTCTGCCGCCAGAGCCTGCCCGAACTCCTGCCGCTAGGATCGGAACGGCAGGTCGCC
TGCCATTTGGTGAGGCATTG

Downstream 100 bases:

>100_bases
AAACGGCAACTGTAAAAACCAACCGTCCGCCGCCTCGCTCGGTGGACCTGCCGACACTCCTTGCTGTGGGCTGGGTTCTC
CTCATGCTCCTCACGGCGCT

Product: transport system permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSAVFRFAGPKILRAGLSILVVVTFTFVVLRASGDPALQILGPSARAPDLEAFRRHWGLDQPLYVQYVRYVLAALHCDFG
NSMLAGKPALQLVFERAPLTLALMLPALALTMLIGIPVGAYAAMHRDTWVDRSVMMVTVFGFTVPSFVLGLLLILIFSVT
LGLFPSGGADRPESFVLPVLTLGLGGAAIIARFTRSAMIEVLSQLYIVAASAKGVTWRQVVRHHAFPNAIIPVLTLFGLM
LGGQVAGAVLVESVFGWPGIGQLLVVSVANRDLAVVQVILLLVALTMTSANLLMDLLYGVFDPRLRGTNSGSQ

Sequences:

>Translated_313_residues
MSAVFRFAGPKILRAGLSILVVVTFTFVVLRASGDPALQILGPSARAPDLEAFRRHWGLDQPLYVQYVRYVLAALHCDFG
NSMLAGKPALQLVFERAPLTLALMLPALALTMLIGIPVGAYAAMHRDTWVDRSVMMVTVFGFTVPSFVLGLLLILIFSVT
LGLFPSGGADRPESFVLPVLTLGLGGAAIIARFTRSAMIEVLSQLYIVAASAKGVTWRQVVRHHAFPNAIIPVLTLFGLM
LGGQVAGAVLVESVFGWPGIGQLLVVSVANRDLAVVQVILLLVALTMTSANLLMDLLYGVFDPRLRGTNSGSQ
>Mature_312_residues
SAVFRFAGPKILRAGLSILVVVTFTFVVLRASGDPALQILGPSARAPDLEAFRRHWGLDQPLYVQYVRYVLAALHCDFGN
SMLAGKPALQLVFERAPLTLALMLPALALTMLIGIPVGAYAAMHRDTWVDRSVMMVTVFGFTVPSFVLGLLLILIFSVTL
GLFPSGGADRPESFVLPVLTLGLGGAAIIARFTRSAMIEVLSQLYIVAASAKGVTWRQVVRHHAFPNAIIPVLTLFGLML
GGQVAGAVLVESVFGWPGIGQLLVVSVANRDLAVVQVILLLVALTMTSANLLMDLLYGVFDPRLRGTNSGSQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=290, Percent_Identity=43.448275862069, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1789888, Length=292, Percent_Identity=36.3013698630137, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1789965, Length=319, Percent_Identity=35.423197492163, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787761, Length=314, Percent_Identity=37.8980891719745, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=33.8762214983713, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=28.6764705882353, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788504, Length=269, Percent_Identity=26.0223048327138, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33524; Mature: 33392

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVFRFAGPKILRAGLSILVVVTFTFVVLRASGDPALQILGPSARAPDLEAFRRHWGLD
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCC
QPLYVQYVRYVLAALHCDFGNSMLAGKPALQLVFERAPLTLALMLPALALTMLIGIPVGA
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHH
YAAMHRDTWVDRSVMMVTVFGFTVPSFVLGLLLILIFSVTLGLFPSGGADRPESFVLPVL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TLGLGGAAIIARFTRSAMIEVLSQLYIVAASAKGVTWRQVVRHHAFPNAIIPVLTLFGLM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
LGGQVAGAVLVESVFGWPGIGQLLVVSVANRDLAVVQVILLLVALTMTSANLLMDLLYGV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDPRLRGTNSGSQ
HCCCCCCCCCCCC
>Mature Secondary Structure 
SAVFRFAGPKILRAGLSILVVVTFTFVVLRASGDPALQILGPSARAPDLEAFRRHWGLD
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCCCC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HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]