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The map label for this gene is appC [H]

Identifier: 13474912

GI number: 13474912

Start: 4766668

End: 4767528

Strand: Direct

Name: appC [H]

Synonym: mlr5897

Alternate gene names: 13474912

Gene position: 4766668-4767528 (Clockwise)

Preceding gene: 13474911

Following gene: 13474916

Centisome position: 67.75

GC content: 63.3

Gene sequence:

>861_bases
ATGAAAACGGCAACTGTAAAAACCAACCGTCCGCCGCCTCGCTCGGTGGACCTGCCGACACTCCTTGCTGTGGGCTGGGT
TCTCCTCATGCTCCTCACGGCGCTCGCCGCGCCGCTGATGGCTCCCCATGAGATCACTTCCATCGACCTGCGCCATCGCC
TGGCGCCGCCCGTCGGCTTTGGCGGAACGATGCTACACGTCCTGGGAACCGACGATCTGGGCCGTGACGTGGCCTCGCGT
CTTTTCTACTCGATCCGCACCAGCTTGCTGGTCGCCTTCGGCGCCACTGCGATCAGCGTGTTGGTCGGTACCGGGATTGG
CTTCATCGCCGCGTATTTCCGCGGGCTCGTCGAGCATGCCCTGCTGCTAATGATCGACGTACAGGCTTCGCTACCATTTC
TAATCGTGGCGCTGGCAATGCTCGCCTGTTTCGGTAATTCGCTGACGCTGTTCGTCGCCCTGATGGGACTTTATGGCTGG
GAGCGGAATGCGCGGTTGGCACGAGGACTGGCAATCACCGCCAGCGCGCAGGGCTATGCGAGCGCAACGCGCCAACTCGG
CGCCCATCCGCTGCGTGTCTATCTGCGGCATATCCTGCCCAACAGCGCGGCGACGCTTCTCGTGGCGGCGACGGTGACCT
TTCCGGAAATCGTCCTGGTGGAAAGCGGACTCTCCTTCCTCGGCCTCGGCGTCCAGCCGCCGATGACCAGCCTGGGTGTC
ATGGTCGCGGCCGGCCGCGAGTATATCACCCGCGCCTCCTGGATGCTGCTCGCTCCAAGCCTCGTCATTGTCATCACGGC
CGTTGCCGTTAGCGTCCTCGGCGACTGGTTGCGCGATAAGCTCGACCCGACCCTCAAATAA

Upstream 100 bases:

>100_bases
TCCTTCTCGTGGCGCTGACCATGACGTCGGCCAACCTGCTGATGGACCTGCTTTATGGCGTGTTCGATCCGCGCTTGCGT
GGAACAAACTCAGGATCGCA

Downstream 100 bases:

>100_bases
CGGTTTCCCAATGCAAAGGAGCTGATCTCCACACTTGTCGACGGCTACGCTCTTGCACGGGACGGGGTGCCGAACCTTCG
CCCGCGGCCGGTATCGACGT

Product: transport system permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKTATVKTNRPPPRSVDLPTLLAVGWVLLMLLTALAAPLMAPHEITSIDLRHRLAPPVGFGGTMLHVLGTDDLGRDVASR
LFYSIRTSLLVAFGATAISVLVGTGIGFIAAYFRGLVEHALLLMIDVQASLPFLIVALAMLACFGNSLTLFVALMGLYGW
ERNARLARGLAITASAQGYASATRQLGAHPLRVYLRHILPNSAATLLVAATVTFPEIVLVESGLSFLGLGVQPPMTSLGV
MVAAGREYITRASWMLLAPSLVIVITAVAVSVLGDWLRDKLDPTLK

Sequences:

>Translated_286_residues
MKTATVKTNRPPPRSVDLPTLLAVGWVLLMLLTALAAPLMAPHEITSIDLRHRLAPPVGFGGTMLHVLGTDDLGRDVASR
LFYSIRTSLLVAFGATAISVLVGTGIGFIAAYFRGLVEHALLLMIDVQASLPFLIVALAMLACFGNSLTLFVALMGLYGW
ERNARLARGLAITASAQGYASATRQLGAHPLRVYLRHILPNSAATLLVAATVTFPEIVLVESGLSFLGLGVQPPMTSLGV
MVAAGREYITRASWMLLAPSLVIVITAVAVSVLGDWLRDKLDPTLK
>Mature_286_residues
MKTATVKTNRPPPRSVDLPTLLAVGWVLLMLLTALAAPLMAPHEITSIDLRHRLAPPVGFGGTMLHVLGTDDLGRDVASR
LFYSIRTSLLVAFGATAISVLVGTGIGFIAAYFRGLVEHALLLMIDVQASLPFLIVALAMLACFGNSLTLFVALMGLYGW
ERNARLARGLAITASAQGYASATRQLGAHPLRVYLRHILPNSAATLLVAATVTFPEIVLVESGLSFLGLGVQPPMTSLGV
MVAAGREYITRASWMLLAPSLVIVITAVAVSVLGDWLRDKLDPTLK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=258, Percent_Identity=32.9457364341085, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789964, Length=257, Percent_Identity=37.3540856031128, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787054, Length=260, Percent_Identity=31.1538461538462, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=34.4262295081967, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787498, Length=258, Percent_Identity=30.6201550387597, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787549, Length=242, Percent_Identity=30.9917355371901, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788505, Length=279, Percent_Identity=25.4480286738351, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30418; Mature: 30418

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTATVKTNRPPPRSVDLPTLLAVGWVLLMLLTALAAPLMAPHEITSIDLRHRLAPPVGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GGTMLHVLGTDDLGRDVASRLFYSIRTSLLVAFGATAISVLVGTGIGFIAAYFRGLVEHA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLLMIDVQASLPFLIVALAMLACFGNSLTLFVALMGLYGWERNARLARGLAITASAQGYA
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCEEEEECCCHHH
SATRQLGAHPLRVYLRHILPNSAATLLVAATVTFPEIVLVESGLSFLGLGVQPPMTSLGV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCHHHHHH
MVAAGREYITRASWMLLAPSLVIVITAVAVSVLGDWLRDKLDPTLK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTATVKTNRPPPRSVDLPTLLAVGWVLLMLLTALAAPLMAPHEITSIDLRHRLAPPVGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
GGTMLHVLGTDDLGRDVASRLFYSIRTSLLVAFGATAISVLVGTGIGFIAAYFRGLVEHA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LLLMIDVQASLPFLIVALAMLACFGNSLTLFVALMGLYGWERNARLARGLAITASAQGYA
HHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHCEEEEECCCHHH
SATRQLGAHPLRVYLRHILPNSAATLLVAATVTFPEIVLVESGLSFLGLGVQPPMTSLGV
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCHHHCCCCCCCCHHHHHH
MVAAGREYITRASWMLLAPSLVIVITAVAVSVLGDWLRDKLDPTLK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]