Click here to switch to the map view.

The map label for this gene is dctD [H]

Identifier: 13474866

GI number: 13474866

Start: 4717620

End: 4718987

Strand: Direct

Name: dctD [H]

Synonym: mlr5842

Alternate gene names: 13474866

Gene position: 4717620-4718987 (Clockwise)

Preceding gene: 13474865

Following gene: 13474867

Centisome position: 67.05

GC content: 60.09

Gene sequence:

>1368_bases
ATGAGTGCTGAATCAGGACCGGTCATTTTTATCGACGATGACGAGGATGTGCTTCGCGCAGCCACGCAGATGCTGAAGCT
TGCCTCGTTCTCACCGAGCGTGTTCGGTTCGGCCGAGGCCGCACTCGCCAGAATCGACGGGAACTTCGATGGCCCTGTCG
TGAGTGACATCCGTATGCCCGGGCTGAACGGACTTCAGCTCTTCGAGCGAGTGAAGGCGATCGACCCGGAAATTCCGGTT
GTCCTGATCACCGGGCATGCCGACGTCGAGCTGGCCGTTGCCGCCATCCAGGATGGCGCCTACGATTTCATCTCGAAGCC
ATATGCGAACGACCGGCTTCTCGTGACGCTGCATCGCGCTTCGGAAAAACGGCGCCTGGTCCTGGAAAACAGACGTCTTA
GGGATGCGGTTGTCCGATCTGCGGGCGATATCCCGCTGATCGGGGAGGCACCGACCATGATTCGATTGCGCGAAACTCTC
CGCCAGATCGCCGATACCGATGTGGATGTCCTTGTGGAAGGCGAGACGGGCACGGGCAAGGAGGTGGTCGCGGATCTGCT
TCACCGCTGGAGCAGACGACGCACGAAGCCCTTCGTTGCCCTGAATTGTGGAGCGCTGCCCGAAAGCGTCATCGATAGCG
AACTTTTCGGGCACGAGGCAGGCGCCTTTACTGGCGCGCAGAGGCGCAGGACCGGTCGCATCGAGCATTCGAACGGAGGG
ACGCTCTTCCTCGACGAAATCGAGTCGATGCCGCCAGCACTCCAGGTGAAGCTTCTGAGGGTGCTTGAGACCCGGCAGAT
CACGCCGCTTGGCACGAACGAAACCCGCAGCATCGACCTTCGTGTCGTGTCGGCTACCAAGGCCGATCTCGGCGATCCGG
CCGCCCGCGGAGATTTCCGGGAAGACCTTTATTTCCGGCTGAATGTGGTGACGCTCCGCATCCCGCCGCTTCGCGAAAGG
CGCGAAGACATCCCGATGCTCTTTGGGCATTTCCTGGAACGCGCCTCCAAACGCTTCAGCAGGCCAGTTCCGGACATCAG
CGCTGGCGTGCGCGATCGCCTCGTGAGCCACAATTGGCCCGGCAATGTCCGTGAACTCGTGCATTTCGCCGATCGCGTTG
CATTGGGACTTGAAAGGCTGGGCACGCCCATTGCATCAGGTCGAAAGGAACAAGCGGTATCAAGCCTCCACTTGTCCGAG
AAGGTCAGCCTTTATGAGGCGACTATCATCCGCGATGCCTTGCAGGAATGCGGCGGCGACGTGAGGCGCACGATCGAAGT
CCTGGGAGTTCCCCGCAAGACCTTCTACGACAAGCTGAAACGACATGGGATAGACACGGCCGATTATCGAAAAACCGCCA
TTGGCTGA

Upstream 100 bases:

>100_bases
TTTCGCAAGAGATCGCACGTGAGCTCGGCGGCTCGTTGCGGCATGATGATGCCGGCCACGGGAGAGGGACTTCCTTCACG
GTCGAGCTGAGGCGAGCGGC

Downstream 100 bases:

>100_bases
AGCCTTCTTGCTTGCATGTCGCGGAAAAGAAATTTCGCCATTCTCGTCCGACTCAAAGGATGCACTATGGGCTAGGTGAA
GCGAGCCTGAGGTCGCTTTC

Product: C4-dicarboxylate transport system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSAESGPVIFIDDDEDVLRAATQMLKLASFSPSVFGSAEAALARIDGNFDGPVVSDIRMPGLNGLQLFERVKAIDPEIPV
VLITGHADVELAVAAIQDGAYDFISKPYANDRLLVTLHRASEKRRLVLENRRLRDAVVRSAGDIPLIGEAPTMIRLRETL
RQIADTDVDVLVEGETGTGKEVVADLLHRWSRRRTKPFVALNCGALPESVIDSELFGHEAGAFTGAQRRRTGRIEHSNGG
TLFLDEIESMPPALQVKLLRVLETRQITPLGTNETRSIDLRVVSATKADLGDPAARGDFREDLYFRLNVVTLRIPPLRER
REDIPMLFGHFLERASKRFSRPVPDISAGVRDRLVSHNWPGNVRELVHFADRVALGLERLGTPIASGRKEQAVSSLHLSE
KVSLYEATIIRDALQECGGDVRRTIEVLGVPRKTFYDKLKRHGIDTADYRKTAIG

Sequences:

>Translated_455_residues
MSAESGPVIFIDDDEDVLRAATQMLKLASFSPSVFGSAEAALARIDGNFDGPVVSDIRMPGLNGLQLFERVKAIDPEIPV
VLITGHADVELAVAAIQDGAYDFISKPYANDRLLVTLHRASEKRRLVLENRRLRDAVVRSAGDIPLIGEAPTMIRLRETL
RQIADTDVDVLVEGETGTGKEVVADLLHRWSRRRTKPFVALNCGALPESVIDSELFGHEAGAFTGAQRRRTGRIEHSNGG
TLFLDEIESMPPALQVKLLRVLETRQITPLGTNETRSIDLRVVSATKADLGDPAARGDFREDLYFRLNVVTLRIPPLRER
REDIPMLFGHFLERASKRFSRPVPDISAGVRDRLVSHNWPGNVRELVHFADRVALGLERLGTPIASGRKEQAVSSLHLSE
KVSLYEATIIRDALQECGGDVRRTIEVLGVPRKTFYDKLKRHGIDTADYRKTAIG
>Mature_454_residues
SAESGPVIFIDDDEDVLRAATQMLKLASFSPSVFGSAEAALARIDGNFDGPVVSDIRMPGLNGLQLFERVKAIDPEIPVV
LITGHADVELAVAAIQDGAYDFISKPYANDRLLVTLHRASEKRRLVLENRRLRDAVVRSAGDIPLIGEAPTMIRLRETLR
QIADTDVDVLVEGETGTGKEVVADLLHRWSRRRTKPFVALNCGALPESVIDSELFGHEAGAFTGAQRRRTGRIEHSNGGT
LFLDEIESMPPALQVKLLRVLETRQITPLGTNETRSIDLRVVSATKADLGDPAARGDFREDLYFRLNVVTLRIPPLRERR
EDIPMLFGHFLERASKRFSRPVPDISAGVRDRLVSHNWPGNVRELVHFADRVALGLERLGTPIASGRKEQAVSSLHLSEK
VSLYEATIIRDALQECGGDVRRTIEVLGVPRKTFYDKLKRHGIDTADYRKTAIG

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=458, Percent_Identity=40.174672489083, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1788550, Length=454, Percent_Identity=37.0044052863436, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1790437, Length=455, Percent_Identity=37.3626373626374, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=35.8050847457627, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=41.3249211356467, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI87082117, Length=247, Percent_Identity=45.3441295546559, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1786524, Length=313, Percent_Identity=39.6166134185303, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1789087, Length=344, Percent_Identity=37.7906976744186, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082152, Length=229, Percent_Identity=48.9082969432314, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=37.6947040498442, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787583, Length=221, Percent_Identity=39.3665158371041, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI87081858, Length=310, Percent_Identity=34.8387096774194, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=34.0080971659919, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50410; Mature: 50279

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAESGPVIFIDDDEDVLRAATQMLKLASFSPSVFGSAEAALARIDGNFDGPVVSDIRMP
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCCEECCCCCC
GLNGLQLFERVKAIDPEIPVVLITGHADVELAVAAIQDGAYDFISKPYANDRLLVTLHRA
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHCCCHHHHCCCCCCCEEEEEEECC
SEKRRLVLENRRLRDAVVRSAGDIPLIGEAPTMIRLRETLRQIADTDVDVLVEGETGTGK
CCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCH
EVVADLLHRWSRRRTKPFVALNCGALPESVIDSELFGHEAGAFTGAQRRRTGRIEHSNGG
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCC
TLFLDEIESMPPALQVKLLRVLETRQITPLGTNETRSIDLRVVSATKADLGDPAARGDFR
EEEEEHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCH
EDLYFRLNVVTLRIPPLRERREDIPMLFGHFLERASKRFSRPVPDISAGVRDRLVSHNWP
HCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
GNVRELVHFADRVALGLERLGTPIASGRKEQAVSSLHLSEKVSLYEATIIRDALQECGGD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VRRTIEVLGVPRKTFYDKLKRHGIDTADYRKTAIG
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
SAESGPVIFIDDDEDVLRAATQMLKLASFSPSVFGSAEAALARIDGNFDGPVVSDIRMP
CCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCCEECCCCCC
GLNGLQLFERVKAIDPEIPVVLITGHADVELAVAAIQDGAYDFISKPYANDRLLVTLHRA
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHCCCHHHHCCCCCCCEEEEEEECC
SEKRRLVLENRRLRDAVVRSAGDIPLIGEAPTMIRLRETLRQIADTDVDVLVEGETGTGK
CCCHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCH
EVVADLLHRWSRRRTKPFVALNCGALPESVIDSELFGHEAGAFTGAQRRRTGRIEHSNGG
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCCEECCCC
TLFLDEIESMPPALQVKLLRVLETRQITPLGTNETRSIDLRVVSATKADLGDPAARGDFR
EEEEEHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCH
EDLYFRLNVVTLRIPPLRERREDIPMLFGHFLERASKRFSRPVPDISAGVRDRLVSHNWP
HCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
GNVRELVHFADRVALGLERLGTPIASGRKEQAVSSLHLSEKVSLYEATIIRDALQECGGD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VRRTIEVLGVPRKTFYDKLKRHGIDTADYRKTAIG
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]