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The map label for this gene is rssA [H]

Identifier: 13474479

GI number: 13474479

Start: 4292055

End: 4293416

Strand: Reverse

Name: rssA [H]

Synonym: mll5372

Alternate gene names: 13474479

Gene position: 4293416-4292055 (Counterclockwise)

Preceding gene: 13474480

Following gene: 13474477

Centisome position: 61.02

GC content: 65.86

Gene sequence:

>1362_bases
ATGAGCCTCAAGCGCCCGCGTTCGCTCAAATGGAGCCTGGTGCTGCGCATCGCCTTACTGCAATGCGCGATGCTGACGCT
GATCATCGTCGGCATTCTCGGCGCGTTGCTCGCCACCGGCCTCATTCCGCACGACTATGAGGACGGCACGATGGACGTGC
TGGCGGATGCGGTGGCGCGTGACGCTGGCGGCAAGCTTGTGCTGCGCGAGACCTCGGATCTGACGAAACTGCGATCCGAA
GTCCCCGACCTCTGGTTCATTATCCGCGACAAGCCGGGGCAGCGGCTGCAGGAAGGCACGGTTCCGGCCATCTTCCAGCC
TTTCGCCGAACTGCTGGACACGATCAGCGACGCGCGTATCGACAATTCCATCGGCGAGAGCGCGCCGCCGGATGCAAAGA
TCCGCTGGACCGAAACGGCCGCGGGCAACGTCCAGATCTTCACCGGCACCAAGGGCGGGCTTTCGCTGCTGCGCCTGCTC
GGACAGGCGCCGCAATTCTTCCTGCAAGGCATATTGCCGCTCGCCGGCCTCATGGCGCTGGCCACGCTCTTCGCGACGCC
GTGGGTGGTGCGCGGCGCGCTGTCGGGTCTTGGCCATGCGGCCGCCGAAGCCGAACGCATCGACATCGACCAGCGCGGCG
TGCAACTGCCGCTGAAGGATGTGCCAAAGGAAGTCACGCCGCTGGTCAAGGCGGTGAACGCCGCCCTTGCGCGCCTCGAC
AAGGGATACGAGCGCCACAAGCGCTTCCTTACCGATGCCGCCCATGAGCTCCGAACGCCGGTCGCCATCCTCAACACACG
CCTGGCCTCGCTGCCGGCGACACCGGAACGGGCACGGCTGCTGCAGGACGCCGCACGGCTTTCGACGCTGACCGACCAGT
TGCTCGACCTGCAACGCCTCGATCGGCAGACCACGCCTTTCGAGAAAGTCGATCTCGTGGCGATCGCGCGCGGCGTCATC
GTCGACCTCGCGCCGATGGCGTTTTCGGCCGGATACGAGATGTCGTTCGAGCCGGAACGGGAAACGGTTTTCGCCACCGG
CGATCGCACCGCGATCGAGCGCGCGGTGACCAACATCGTGCAGAACGCCATCGAGCATGGCGGCAGGGCTGGCAAGATCA
CCGTCAGTGTCACCGCTTCCGCTGTCATCGAGGTGCGGGACGAAGGCGACGGCGTACCGCCAGACGAGCGCGAACGCATC
TTCGAGCCCTTCTACCGGCTGCGCCCGCAGGATCACGGCGCCGGGCTCGGCCTCAACCTGGTGCAGGAAATCATGCAGTT
GCATGGCGGGCGCATCGATATCCTCGACGGCAAGCCGAGCGGCGCCTGCTTCCGGATGAGTTTTCGCGCCTTGCCGGCCT
GA

Upstream 100 bases:

>100_bases
CGCCTGCGCCGCAAGCTCGCCGACGCCGATGCCGGCGTGACGATCAACGGCATTCGCGGCGTCGGCTATCTGCTGCGCGA
AACGACGTGAGCCTCAATCG

Downstream 100 bases:

>100_bases
AGCGCGTCGCCTGAACCCGTCCAGGCACTTCGCGCTTCAGGCGGGTGTGGGTCAACCAATCGCTGATGTTCGGCTAAAAT
CCGGCTTCGCCGCCGGCGAT

Product: two-component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSLKRPRSLKWSLVLRIALLQCAMLTLIIVGILGALLATGLIPHDYEDGTMDVLADAVARDAGGKLVLRETSDLTKLRSE
VPDLWFIIRDKPGQRLQEGTVPAIFQPFAELLDTISDARIDNSIGESAPPDAKIRWTETAAGNVQIFTGTKGGLSLLRLL
GQAPQFFLQGILPLAGLMALATLFATPWVVRGALSGLGHAAAEAERIDIDQRGVQLPLKDVPKEVTPLVKAVNAALARLD
KGYERHKRFLTDAAHELRTPVAILNTRLASLPATPERARLLQDAARLSTLTDQLLDLQRLDRQTTPFEKVDLVAIARGVI
VDLAPMAFSAGYEMSFEPERETVFATGDRTAIERAVTNIVQNAIEHGGRAGKITVSVTASAVIEVRDEGDGVPPDERERI
FEPFYRLRPQDHGAGLGLNLVQEIMQLHGGRIDILDGKPSGACFRMSFRALPA

Sequences:

>Translated_453_residues
MSLKRPRSLKWSLVLRIALLQCAMLTLIIVGILGALLATGLIPHDYEDGTMDVLADAVARDAGGKLVLRETSDLTKLRSE
VPDLWFIIRDKPGQRLQEGTVPAIFQPFAELLDTISDARIDNSIGESAPPDAKIRWTETAAGNVQIFTGTKGGLSLLRLL
GQAPQFFLQGILPLAGLMALATLFATPWVVRGALSGLGHAAAEAERIDIDQRGVQLPLKDVPKEVTPLVKAVNAALARLD
KGYERHKRFLTDAAHELRTPVAILNTRLASLPATPERARLLQDAARLSTLTDQLLDLQRLDRQTTPFEKVDLVAIARGVI
VDLAPMAFSAGYEMSFEPERETVFATGDRTAIERAVTNIVQNAIEHGGRAGKITVSVTASAVIEVRDEGDGVPPDERERI
FEPFYRLRPQDHGAGLGLNLVQEIMQLHGGRIDILDGKPSGACFRMSFRALPA
>Mature_452_residues
SLKRPRSLKWSLVLRIALLQCAMLTLIIVGILGALLATGLIPHDYEDGTMDVLADAVARDAGGKLVLRETSDLTKLRSEV
PDLWFIIRDKPGQRLQEGTVPAIFQPFAELLDTISDARIDNSIGESAPPDAKIRWTETAAGNVQIFTGTKGGLSLLRLLG
QAPQFFLQGILPLAGLMALATLFATPWVVRGALSGLGHAAAEAERIDIDQRGVQLPLKDVPKEVTPLVKAVNAALARLDK
GYERHKRFLTDAAHELRTPVAILNTRLASLPATPERARLLQDAARLSTLTDQLLDLQRLDRQTTPFEKVDLVAIARGVIV
DLAPMAFSAGYEMSFEPERETVFATGDRTAIERAVTNIVQNAIEHGGRAGKITVSVTASAVIEVRDEGDGVPPDERERIF
EPFYRLRPQDHGAGLGLNLVQEIMQLHGGRIDILDGKPSGACFRMSFRALPA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=239, Percent_Identity=33.4728033472803, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788279, Length=280, Percent_Identity=26.4285714285714, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.1304347826087, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786783, Length=285, Percent_Identity=24.5614035087719, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.7037037037037, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=260, Percent_Identity=27.3076923076923, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=218, Percent_Identity=28.4403669724771, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=27.1889400921659, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=28.1632653061224, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790436, Length=204, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49294; Mature: 49162

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRPRSLKWSLVLRIALLQCAMLTLIIVGILGALLATGLIPHDYEDGTMDVLADAVAR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
DAGGKLVLRETSDLTKLRSEVPDLWFIIRDKPGQRLQEGTVPAIFQPFAELLDTISDARI
CCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
DNSIGESAPPDAKIRWTETAAGNVQIFTGTKGGLSLLRLLGQAPQFFLQGILPLAGLMAL
CCCCCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ATLFATPWVVRGALSGLGHAAAEAERIDIDQRGVQLPLKDVPKEVTPLVKAVNAALARLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
KGYERHKRFLTDAAHELRTPVAILNTRLASLPATPERARLLQDAARLSTLTDQLLDLQRL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DRQTTPFEKVDLVAIARGVIVDLAPMAFSAGYEMSFEPERETVFATGDRTAIERAVTNIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
QNAIEHGGRAGKITVSVTASAVIEVRDEGDGVPPDERERIFEPFYRLRPQDHGAGLGLNL
HHHHHCCCCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHH
VQEIMQLHGGRIDILDGKPSGACFRMSFRALPA
HHHHHHHCCCEEEEECCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SLKRPRSLKWSLVLRIALLQCAMLTLIIVGILGALLATGLIPHDYEDGTMDVLADAVAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
DAGGKLVLRETSDLTKLRSEVPDLWFIIRDKPGQRLQEGTVPAIFQPFAELLDTISDARI
CCCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
DNSIGESAPPDAKIRWTETAAGNVQIFTGTKGGLSLLRLLGQAPQFFLQGILPLAGLMAL
CCCCCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ATLFATPWVVRGALSGLGHAAAEAERIDIDQRGVQLPLKDVPKEVTPLVKAVNAALARLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
KGYERHKRFLTDAAHELRTPVAILNTRLASLPATPERARLLQDAARLSTLTDQLLDLQRL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DRQTTPFEKVDLVAIARGVIVDLAPMAFSAGYEMSFEPERETVFATGDRTAIERAVTNIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHH
QNAIEHGGRAGKITVSVTASAVIEVRDEGDGVPPDERERIFEPFYRLRPQDHGAGLGLNL
HHHHHCCCCCCEEEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHH
VQEIMQLHGGRIDILDGKPSGACFRMSFRALPA
HHHHHHHCCCEEEEECCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA