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The map label for this gene is ybiC [C]

Identifier: 13474334

GI number: 13474334

Start: 4131594

End: 4132595

Strand: Reverse

Name: ybiC [C]

Synonym: mll5197

Alternate gene names: 13474334

Gene position: 4132595-4131594 (Counterclockwise)

Preceding gene: 13474335

Following gene: 13474332

Centisome position: 58.73

GC content: 67.86

Gene sequence:

>1002_bases
ATGCAACTCAGTCTCGACCAGGCAAGAGGACTGTGCCGGATGGCGGCACTCGGCGCCGGCGCCAATGAGGAGGCGGCGCA
GTCGCTCACCGCGTCGATCATCGCCGCCGAGGCGGAAGGGCTTTCGACTGTCGGCCTGTCGCATTTCATCGACTATCTCG
AAGCCCTGGAGGCCGGGCGCATCGACGGCAATGCCGATCCGGTGATCACCAGGCCGGCGCTGGCCGTCTACCTTTCCGAC
GCACGCGGCGGGCTGGCGCATACCGGCTTCGACCGGACGATCGACGACCTTGCCAAGGCGGCAAAACTGTTCGGCGTCGC
CATCTTCTCGCAGAAGAACGCCTATACATGCGGCGCGCTCGGCTACTTTACCGGAAGGCTGGCGGCACAGGGGCTGGTGT
CCTTCGCCGCGACCAACGGCCCGGCCGTTCTTGCCGGCTCGGGCTCGGTCAAGCCGGTCTATTGCACCAATCCGATGTCG
TTTGCCGCGCCCGCCGCCGACGGCGCGCCGCTGGTCATCGACCAGTCATCGAGCGCCACCGCCTTCGTCAACATTCGCAA
GGCGGCCGAAGACGGCAAGAAGATCCCCGAAGGCTGGGCGCTGGACGCCAGTGGCAACCCGACCACCGACCCGGCCGCCG
CCATGAAGGGCGCCATGCTTGCCTTTGGCGGCCAGCGCGGCGCCAACATCGCGCTGATGGTCGAAGTGTTGGCTGCGGGC
ATTTCCGGGGCCAACTGGTCGCTCGATGCGCCCTGGTTCACCGGCGGGCCCGACAGCCCAGGCACCGGCCTGTTCGTGCT
GGCTATCGAGCCCAAGCTGCTCGATCCGGATTTCGAACAGCGCATGAAGGACCAGCTCGACCGCCTGCGCCGCCGCTTCG
GCGTGCATGTGCCGGGCCGCGCCCGGGCGGAAGCCGCCGAGAAGGCGCAGGCGCGCGGCATCACCGCGCCCAAGGCGGTG
GTGCAGCGTATTTCCGAATTCGCCGAGCGCTATTCGACCTGA

Upstream 100 bases:

>100_bases
TAGGAAGAGGTCGTTAGCGAACGGTGAGTAGCGAATAGGGCGTCTCACTATTCGCCCTACTCGCTATTCCCTATTCGCTA
CTCACTTAGGAACAATTGCG

Downstream 100 bases:

>100_bases
ATTGCGACGAACGAATGCCTGGCCGGTGCCGGACCTTCAACAGTCCCTTTCACCGGGGATATTCGAGCTGCATGGCGACG
AAGTCGGCCGTGCGTGCACC

Product: malate dehydrogenase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGRIDGNADPVITRPALAVYLSD
ARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGALGYFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMS
FAAPAADGAPLVIDQSSSATAFVNIRKAAEDGKKIPEGWALDASGNPTTDPAAAMKGAMLAFGGQRGANIALMVEVLAAG
ISGANWSLDAPWFTGGPDSPGTGLFVLAIEPKLLDPDFEQRMKDQLDRLRRRFGVHVPGRARAEAAEKAQARGITAPKAV
VQRISEFAERYST

Sequences:

>Translated_333_residues
MQLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGRIDGNADPVITRPALAVYLSD
ARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGALGYFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMS
FAAPAADGAPLVIDQSSSATAFVNIRKAAEDGKKIPEGWALDASGNPTTDPAAAMKGAMLAFGGQRGANIALMVEVLAAG
ISGANWSLDAPWFTGGPDSPGTGLFVLAIEPKLLDPDFEQRMKDQLDRLRRRFGVHVPGRARAEAAEKAQARGITAPKAV
VQRISEFAERYST
>Mature_333_residues
MQLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGRIDGNADPVITRPALAVYLSD
ARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGALGYFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMS
FAAPAADGAPLVIDQSSSATAFVNIRKAAEDGKKIPEGWALDASGNPTTDPAAAMKGAMLAFGGQRGANIALMVEVLAAG
ISGANWSLDAPWFTGGPDSPGTGLFVLAIEPKLLDPDFEQRMKDQLDRLRRRFGVHVPGRARAEAAEKAQARGITAPKAV
VQRISEFAERYST

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=260, Percent_Identity=26.5384615384615, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786727, Length=341, Percent_Identity=24.633431085044, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790000, Length=336, Percent_Identity=22.3214285714286, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536633, Length=326, Percent_Identity=23.9263803680982, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17507179, Length=327, Percent_Identity=22.9357798165138, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667904, Length=267, Percent_Identity=30.3370786516854, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45553211, Length=267, Percent_Identity=30.3370786516854, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667912, Length=267, Percent_Identity=30.3370786516854, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24667908, Length=267, Percent_Identity=30.3370786516854, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658010, Length=335, Percent_Identity=22.089552238806, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 34512; Mature: 34512

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGR
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
IDGNADPVITRPALAVYLSDARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGAL
CCCCCCCEEECCEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHEECCCCCEECHHH
GYFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMSFAAPAADGAPLVIDQSSSAT
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCE
AFVNIRKAAEDGKKIPEGWALDASGNPTTDPAAAMKGAMLAFGGQRGANIALMVEVLAAG
EEEEEHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHCHHEEECCCCCCCHHHHHHHHHHC
ISGANWSLDAPWFTGGPDSPGTGLFVLAIEPKLLDPDFEQRMKDQLDRLRRRFGVHVPGR
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ARAEAAEKAQARGITAPKAVVQRISEFAERYST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLSLDQARGLCRMAALGAGANEEAAQSLTASIIAAEAEGLSTVGLSHFIDYLEALEAGR
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
IDGNADPVITRPALAVYLSDARGGLAHTGFDRTIDDLAKAAKLFGVAIFSQKNAYTCGAL
CCCCCCCEEECCEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHEECCCCCEECHHH
GYFTGRLAAQGLVSFAATNGPAVLAGSGSVKPVYCTNPMSFAAPAADGAPLVIDQSSSAT
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCE
AFVNIRKAAEDGKKIPEGWALDASGNPTTDPAAAMKGAMLAFGGQRGANIALMVEVLAAG
EEEEEHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHCHHEEECCCCCCCHHHHHHHHHHC
ISGANWSLDAPWFTGGPDSPGTGLFVLAIEPKLLDPDFEQRMKDQLDRLRRRFGVHVPGR
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ARAEAAEKAQARGITAPKAVVQRISEFAERYST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]