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The map label for this gene is epr [H]

Identifier: 13474266

GI number: 13474266

Start: 4054177

End: 4055349

Strand: Reverse

Name: epr [H]

Synonym: mll5116

Alternate gene names: 13474266

Gene position: 4055349-4054177 (Counterclockwise)

Preceding gene: 13474267

Following gene: 13474264

Centisome position: 57.64

GC content: 68.88

Gene sequence:

>1173_bases
GTGCCGACGCCCCGACCAGAACCAGCCGCGCCGCCCGGCAACAACCAGGCCGGCCCGCCGGCCGGCGGGCCGATTATCTC
GCCAACCGATCTCATCGCCATTCAGCCGCCGCGCGCCGTGGCCGGCGACTTCGTGCCCGACGAGGTGCTGGTGACGGTCG
ACGGCGATGCCGGCGCCGTGCAGCAGATCGCCGCCTCCTTCGGCCTCGAAGTGCGCTCGCAGCGCCAGTCACGCCTGCTC
GGCACGACATTGGTGCGCTTCGGCATTCCCGACGGCCGCCCCGTCGGCGTCGTGCTGGCGCAGCTTGCCGCCGACGGCCG
CACGCAGCGGCGCGAGCCCAACCACATCTATTCGCTGCAGCAGGCCGCCGGCATCGTCAACTATGCTTTCGATCGCATCG
CGCTCGATGCCAAACAGGCGAGCGGCGAAAACATCCGCGTCGCCGTCATCGATACCGGTATAGACGACACCAATCCGGCA
TTGGCCGGCGTCATCGCCGCGCAGTTCGACGCCATGCCCGGCGTGCCTGTCGAAAAGCGCGACCATGGCACGTCGATCGA
CGGGCTGATCGCCGGCGTCGGCGCGCTGGAAGGCATGGCGCCGGGCGCCAGGATCTACCACGCCCGCGCCTTCGAGGGCG
GCAAGTCGACCATGGACGTCATCCTGTCGGCGCTCGACTGGGCGGCGGAACAGAATGTCAGCATCATCAATATGAGCTTC
GTCGGGCCGAAGAACGACCTGCTCGGCGCCGCCTGCCGCAATGCCCGCGCGCTCGGCATGGTACTGGTCGCCGCCGCCGG
CAACAACGGGCCGAAGGCGCCCTATGGCTACCCCGCGGCCTTCGACGGCGTCATCGCGGTGACCGCCACCGACGCCAAGG
ACGCTCTGATGCCGCAGGCCAATCGCGGCGCCTATGTCTTCATTTCCGCGCCCGGCGTCGAGATGGTGGCGCCAAGCGGC
GCCGGCTCGGATGTCGTTACCGGCACCTCGTTCGCCGCGGCGATCGTCAGCGGTGCCATCGCCAATCTCCTCCATGCTTC
GCCCGGGCGTACCGCCGACGACATCGAGAAGGCCTTGGCTGCCACCGCCAAGGATCTCGGCCCGAAGGGGCGCGACAATG
ATTTCGGCTATGGGCTGCTGGACATCAAGGCGGCCGAGGCAGCGAAAGAGTAG

Upstream 100 bases:

>100_bases
CGACAATGCCGGCAATGCGGGGACTGCCCAGGCAGGCGCCGTCTTTCTTCCCGCCCTGATCGTCGACCTGTTTCCCAATC
CGGTCGCGCCTCCGGCACCG

Downstream 100 bases:

>100_bases
GTTTTTCCCTGAGCTTCGGGGCTATGCCGCCGGGAGCTGCCGGGTTCGGCCGATCTGCAGAAGCAACGCGGATGCCAGAC
AAAGCCCAACGACCGCCAGC

Product: extracellular protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPTPRPEPAAPPGNNQAGPPAGGPIISPTDLIAIQPPRAVAGDFVPDEVLVTVDGDAGAVQQIAASFGLEVRSQRQSRLL
GTTLVRFGIPDGRPVGVVLAQLAADGRTQRREPNHIYSLQQAAGIVNYAFDRIALDAKQASGENIRVAVIDTGIDDTNPA
LAGVIAAQFDAMPGVPVEKRDHGTSIDGLIAGVGALEGMAPGARIYHARAFEGGKSTMDVILSALDWAAEQNVSIINMSF
VGPKNDLLGAACRNARALGMVLVAAAGNNGPKAPYGYPAAFDGVIAVTATDAKDALMPQANRGAYVFISAPGVEMVAPSG
AGSDVVTGTSFAAAIVSGAIANLLHASPGRTADDIEKALAATAKDLGPKGRDNDFGYGLLDIKAAEAAKE

Sequences:

>Translated_390_residues
MPTPRPEPAAPPGNNQAGPPAGGPIISPTDLIAIQPPRAVAGDFVPDEVLVTVDGDAGAVQQIAASFGLEVRSQRQSRLL
GTTLVRFGIPDGRPVGVVLAQLAADGRTQRREPNHIYSLQQAAGIVNYAFDRIALDAKQASGENIRVAVIDTGIDDTNPA
LAGVIAAQFDAMPGVPVEKRDHGTSIDGLIAGVGALEGMAPGARIYHARAFEGGKSTMDVILSALDWAAEQNVSIINMSF
VGPKNDLLGAACRNARALGMVLVAAAGNNGPKAPYGYPAAFDGVIAVTATDAKDALMPQANRGAYVFISAPGVEMVAPSG
AGSDVVTGTSFAAAIVSGAIANLLHASPGRTADDIEKALAATAKDLGPKGRDNDFGYGLLDIKAAEAAKE
>Mature_389_residues
PTPRPEPAAPPGNNQAGPPAGGPIISPTDLIAIQPPRAVAGDFVPDEVLVTVDGDAGAVQQIAASFGLEVRSQRQSRLLG
TTLVRFGIPDGRPVGVVLAQLAADGRTQRREPNHIYSLQQAAGIVNYAFDRIALDAKQASGENIRVAVIDTGIDDTNPAL
AGVIAAQFDAMPGVPVEKRDHGTSIDGLIAGVGALEGMAPGARIYHARAFEGGKSTMDVILSALDWAAEQNVSIINMSFV
GPKNDLLGAACRNARALGMVLVAAAGNNGPKAPYGYPAAFDGVIAVTATDAKDALMPQANRGAYVFISAPGVEMVAPSGA
GSDVVTGTSFAAAIVSGAIANLLHASPGRTADDIEKALAATAKDLGPKGRDNDFGYGLLDIKAAEAAKE

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=269, Percent_Identity=27.8810408921933, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 39780; Mature: 39649

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPRPEPAAPPGNNQAGPPAGGPIISPTDLIAIQPPRAVAGDFVPDEVLVTVDGDAGAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCCEEEEEECCCCHHH
QQIAASFGLEVRSQRQSRLLGTTLVRFGIPDGRPVGVVLAQLAADGRTQRREPNHIYSLQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
QAAGIVNYAFDRIALDAKQASGENIRVAVIDTGIDDTNPALAGVIAAQFDAMPGVPVEKR
HHHHHHHHHHHHHEEEHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DHGTSIDGLIAGVGALEGMAPGARIYHARAFEGGKSTMDVILSALDWAAEQNVSIINMSF
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
VGPKNDLLGAACRNARALGMVLVAAAGNNGPKAPYGYPAAFDGVIAVTATDAKDALMPQA
CCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
NRGAYVFISAPGVEMVAPSGAGSDVVTGTSFAAAIVSGAIANLLHASPGRTADDIEKALA
CCCEEEEEECCCCEEECCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ATAKDLGPKGRDNDFGYGLLDIKAAEAAKE
HHHHHCCCCCCCCCCCCEEEEEEHHHHCCC
>Mature Secondary Structure 
PTPRPEPAAPPGNNQAGPPAGGPIISPTDLIAIQPPRAVAGDFVPDEVLVTVDGDAGAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHCCCCCCCEEEEEECCCCHHH
QQIAASFGLEVRSQRQSRLLGTTLVRFGIPDGRPVGVVLAQLAADGRTQRREPNHIYSLQ
HHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
QAAGIVNYAFDRIALDAKQASGENIRVAVIDTGIDDTNPALAGVIAAQFDAMPGVPVEKR
HHHHHHHHHHHHHEEEHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
DHGTSIDGLIAGVGALEGMAPGARIYHARAFEGGKSTMDVILSALDWAAEQNVSIINMSF
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEE
VGPKNDLLGAACRNARALGMVLVAAAGNNGPKAPYGYPAAFDGVIAVTATDAKDALMPQA
CCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCC
NRGAYVFISAPGVEMVAPSGAGSDVVTGTSFAAAIVSGAIANLLHASPGRTADDIEKALA
CCCEEEEEECCCCEEECCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ATAKDLGPKGRDNDFGYGLLDIKAAEAAKE
HHHHHCCCCCCCCCCCCEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2116590; 3142851; 7934828; 9384377 [H]