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The map label for this gene is czcN [H]

Identifier: 13473754

GI number: 13473754

Start: 3542208

End: 3542843

Strand: Reverse

Name: czcN [H]

Synonym: mll4454

Alternate gene names: 13473754

Gene position: 3542843-3542208 (Counterclockwise)

Preceding gene: 13473764

Following gene: 13473753

Centisome position: 50.35

GC content: 63.36

Gene sequence:

>636_bases
ATGAGCTATGCCTCCCTCAAGCCGGTTTCAGAGGCTTTCGTGCAGCGCAAGCGGCTGATCTTCGTGCGGGTGGCGGCGGT
GCTGGCGGTGCTGCTGCTGTTCCTCACCAAGCCGGCGCTCAGCGAGGGCTCGAACGGTCACGAAGCGCTCGAATTCCTGG
GCTTCTGCCTGGTGCTCGCCTGCGTTGCCGGCCGGCTGTGGAGCATCCTCTATGTCGGCGGCAAGAAGAACGAGGAGCTG
GTTTCGACGGGGCCGTTTTCGATGAGCCAGAACCCCCTCTATTTCTTCTCGACGGTGGGTGCGGTCGGCATCGGTCTGCT
CTACGGCTCGCTGGTGGCGGCGGCCGTGCTTGGCGTCGCCAGCTTCCTCATCTTCCGCGTCACGGCGCGCAAGGAAGCCG
AATATCTCTTGGGCAAGTTCGGCCCGGCCTATACCGCCTATATCAAGACGACGCCGCGCTTCTGGCCGAACCCGCTGCTC
TACCGCGACGACGACCAGCTGCAGTTCTCGACGCGCGCGCTCAAGCGCACCTTCTTTGACGGGCTCTATTTCCTCGCCAT
CTTCCCGGCCATCGAACTGATCGAGTATTTGCGGGAGACGGGCCTGCTGTTCCCGGCCTTCGTCACGCTGTACTGA

Upstream 100 bases:

>100_bases
GAACGCCGCGTGCTGCGCTGATAGAAGGTGACCGCCTTGTATCCGCCATCAATGGCGCGCCCCAGTGGCGAACCCGCAAT
CCGTGCTCCAGGAAACACGA

Downstream 100 bases:

>100_bases
TCGGCCATTGTCCGGTTAATTTGCGGGTCATGCAGCACTTCGAGGAGCCAGGAGTAGTATCGGCTGAAGACGGTGTCACA
GTCTTCATGGCCGAACACGC

Product: nickel-cobalt-cadmium resistance protein NCCN

Products: NA

Alternate protein names: Cation efflux system protein CzcN [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSYASLKPVSEAFVQRKRLIFVRVAAVLAVLLLFLTKPALSEGSNGHEALEFLGFCLVLACVAGRLWSILYVGGKKNEEL
VSTGPFSMSQNPLYFFSTVGAVGIGLLYGSLVAAAVLGVASFLIFRVTARKEAEYLLGKFGPAYTAYIKTTPRFWPNPLL
YRDDDQLQFSTRALKRTFFDGLYFLAIFPAIELIEYLRETGLLFPAFVTLY

Sequences:

>Translated_211_residues
MSYASLKPVSEAFVQRKRLIFVRVAAVLAVLLLFLTKPALSEGSNGHEALEFLGFCLVLACVAGRLWSILYVGGKKNEEL
VSTGPFSMSQNPLYFFSTVGAVGIGLLYGSLVAAAVLGVASFLIFRVTARKEAEYLLGKFGPAYTAYIKTTPRFWPNPLL
YRDDDQLQFSTRALKRTFFDGLYFLAIFPAIELIEYLRETGLLFPAFVTLY
>Mature_210_residues
SYASLKPVSEAFVQRKRLIFVRVAAVLAVLLLFLTKPALSEGSNGHEALEFLGFCLVLACVAGRLWSILYVGGKKNEELV
STGPFSMSQNPLYFFSTVGAVGIGLLYGSLVAAAVLGVASFLIFRVTARKEAEYLLGKFGPAYTAYIKTTPRFWPNPLLY
RDDDQLQFSTRALKRTFFDGLYFLAIFPAIELIEYLRETGLLFPAFVTLY

Specific function: Component of the CZC cation-efflux system that confers resistance to cobalt, zinc and cadmium [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.xylosoxydans nccN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 23439; Mature: 23308

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYASLKPVSEAFVQRKRLIFVRVAAVLAVLLLFLTKPALSEGSNGHEALEFLGFCLVLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
CVAGRLWSILYVGGKKNEELVSTGPFSMSQNPLYFFSTVGAVGIGLLYGSLVAAAVLGVA
HHHHHHHHHHEECCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLIFRVTARKEAEYLLGKFGPAYTAYIKTTPRFWPNPLLYRDDDQLQFSTRALKRTFFD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
GLYFLAIFPAIELIEYLRETGLLFPAFVTLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
SYASLKPVSEAFVQRKRLIFVRVAAVLAVLLLFLTKPALSEGSNGHEALEFLGFCLVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
CVAGRLWSILYVGGKKNEELVSTGPFSMSQNPLYFFSTVGAVGIGLLYGSLVAAAVLGVA
HHHHHHHHHHEECCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLIFRVTARKEAEYLLGKFGPAYTAYIKTTPRFWPNPLLYRDDDQLQFSTRALKRTFFD
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
GLYFLAIFPAIELIEYLRETGLLFPAFVTLY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9044283; 7766206 [H]