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The map label for this gene is lysM [H]

Identifier: 13473764

GI number: 13473764

Start: 3551847

End: 3552275

Strand: Reverse

Name: lysM [H]

Synonym: mll4468

Alternate gene names: 13473764

Gene position: 3552275-3551847 (Counterclockwise)

Preceding gene: 13473766

Following gene: 13473754

Centisome position: 50.49

GC content: 65.03

Gene sequence:

>429_bases
ATGCTCAGTGAAGCCGAACAGGCGCTGCTTTCCCTGCTGCGTTCCAACGCCCGTGCTTCGACGGCCGAACTGGCGCGGCG
TCTCGGCGTGTCGCGCACCACGGTGCAGAGCCGGATCGAGCGGCTGGAGCAGCGCGGCATCATATCAGGGTATGGCGTCA
AGCTCTCCGCCGACTATGAACAGGGCCTGGTCAAGGCGCATGTGTTGCTCACCGTCACGCCCAAGCTCGCCGACAAGGTG
GTGCGCGCCCTGCAGGCGCTGCCGCCGGTCAGGACGCTGCATTCGGTGAGCGGCAATTTCGACATGATCGTCATCGTCGA
CGCGCCGTCGATCCGCGACCTAGACGCGCTGCTCGACCAGATCGGCGCCATGGACGGGGTCGAGCGGACCTCATCGTCGA
TCATTTTGTCGACGCGGATCGATCGGTGA

Upstream 100 bases:

>100_bases
GAATTGGCGGGAATCATCGCAGCTTGCCTGTCGAAAGGAAGCGTGAAATCTGGCAGAGTGAACCCTATCTTTAGTCGATC
CGCCGAAGGGATTTGTCAAA

Downstream 100 bases:

>100_bases
GCGACAAGCCCGTACCGATTTGCAAAAACCCGGCAGGGTGCCCACGCCCAGTTCGATCGCCTGATCACCGGAATACCTCA
AGACGCCGAACCCACCGACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLSEAEQALLSLLRSNARASTAELARRLGVSRTTVQSRIERLEQRGIISGYGVKLSADYEQGLVKAHVLLTVTPKLADKV
VRALQALPPVRTLHSVSGNFDMIVIVDAPSIRDLDALLDQIGAMDGVERTSSSIILSTRIDR

Sequences:

>Translated_142_residues
MLSEAEQALLSLLRSNARASTAELARRLGVSRTTVQSRIERLEQRGIISGYGVKLSADYEQGLVKAHVLLTVTPKLADKV
VRALQALPPVRTLHSVSGNFDMIVIVDAPSIRDLDALLDQIGAMDGVERTSSSIILSTRIDR
>Mature_142_residues
MLSEAEQALLSLLRSNARASTAELARRLGVSRTTVQSRIERLEQRGIISGYGVKLSADYEQGLVKAHVLLTVTPKLADKV
VRALQALPPVRTLHSVSGNFDMIVIVDAPSIRDLDALLDQIGAMDGVERTSSSIILSTRIDR

Specific function: In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the diaminopimelate pathway [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=140, Percent_Identity=27.8571428571429, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 15434; Mature: 15434

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEAEQALLSLLRSNARASTAELARRLGVSRTTVQSRIERLEQRGIISGYGVKLSADYE
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHH
QGLVKAHVLLTVTPKLADKVVRALQALPPVRTLHSVSGNFDMIVIVDAPSIRDLDALLDQ
HHHHHHHHHEEECHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
IGAMDGVERTSSSIILSTRIDR
HCCCCCHHHCCCCEEEEECCCC
>Mature Secondary Structure
MLSEAEQALLSLLRSNARASTAELARRLGVSRTTVQSRIERLEQRGIISGYGVKLSADYE
CCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHH
QGLVKAHVLLTVTPKLADKVVRALQALPPVRTLHSVSGNFDMIVIVDAPSIRDLDALLDQ
HHHHHHHHHEEECHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
IGAMDGVERTSSSIILSTRIDR
HCCCCCHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311 [H]