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The map label for this gene is sucC

Identifier: 13473641

GI number: 13473641

Start: 3429123

End: 3430316

Strand: Reverse

Name: sucC

Synonym: mll4306

Alternate gene names: 13473641

Gene position: 3430316-3429123 (Counterclockwise)

Preceding gene: 13473642

Following gene: 13473640

Centisome position: 48.75

GC content: 62.98

Gene sequence:

>1194_bases
ATGAACATCCATGAATATCAAGGCAAGGCGCTGCTGAAGAGCTTTGGCGCGCCGGTGGCCGAAGGCGTGCCGGTGTTCAA
GGCGAGCGAGGCGGAAGCCGCGGCACGCGCGCTGCCCGGCCCGCTCTATGTGGTGAAGAGCCAGATCCATGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAACTGTCGCCCGACGCCAAGGGCGGCGTGCGGCTGGCGAAGTCGGTCGCCGACGTCGTC
GCCAACGCCAACGAGATGCTCGGCCACACGCTGGTGACCAAGCAGACCGGCCCGGCCGGCAAGCAGGTCAACCGCCTCTA
TATCGAGGACGGCGCCGATATCGAGCGGGAACTTTATCTGTCGATCCTGGTCGACCGTTCCGTCGGCCGCATCGCCTTCG
TCGTTTCGACCGAAGGCGGCATGGACATCGAGGCGGTCGCCCACGACACGCCGGAAAAGGTCATCACCGTCGCCATCGAC
CCGGAAAGGGGCGTGACGGCGGATGATGTGAAGAAGCTCAACGCAGCCCTCAAGCTCGACGGCGACGCCGCCAAGGATGG
CGGCACGCTGTTCCCGATCCTCTACAAGGCCTTCATCGAGAAGGACATGAGCCTGCTCGAGGTCAATCCGCTGATCGTCA
TGAAGAACGGCCGGCTGCGCGTGCTCGACGCAAAAGTGTCGTTCGACAACAACGCGCTGTTCCGCCACCCGGACGTGCTC
GAACTGCGCGACACCACTGAAGAGGACGAGAAGGAAATCGAGGCGTCGAAATACGACCTCGCCTATGTCGCGCTCGACGG
CAATATCGGCTGCATGGTCAACGGCGCCGGCCTCGCCATGGCGACGATGGACATCATCAAGCTCTATGGCGCCGAGCCCG
CCAACTTCCTCGATGTCGGCGGCGGTGCCTCCAAGGAGAAAGTGACGGCGGCGTTCAAGATCATCACCAAGGATCCGGCG
GTCAAAGGCATACTGATCAACATCTTCGGCGGCATCATGAAGTGCGACATCATCGCCGAGGGCGTGATCGCCGCGGTCAA
GGAAGTCGGGCTGGAAGTGCCGCTGGTGGTGCGTCTGGAAGGCACCAATGCCGAACTCGGCAAGAAGATCATCAACGACA
GCGGCCTCAACGTCGTGTCGGCCGATGATCTCGACGACGCAGCCAAGAAGATCGTCGCGGCGGTGAAGGGCTGA

Upstream 100 bases:

>100_bases
GCCTGACCGAGGCCTGCGTCAAGATCGCGCCGCAGCTCGCTTCGAAGTGAATCCCACCAAAACGTCGACCCCGGCAAAAA
CGACCTGGAGATAGCTCCCG

Downstream 100 bases:

>100_bases
GCCTGTGCCTCCGCGCAAGATAAACCTGGTCGAGGCGGCGGACGCGAAGATCACCAAGGTCTTCGATCCGCATATTGCCG
GCGACGTCAATGACAGCCAG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFKELSPDAKGGVRLAKSVADVV
ANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYLSILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAID
PERGVTADDVKKLNAALKLDGDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVL
ELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITKDPA
VKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLEGTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG

Sequences:

>Translated_397_residues
MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFKELSPDAKGGVRLAKSVADVV
ANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYLSILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAID
PERGVTADDVKKLNAALKLDGDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVL
ELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITKDPA
VKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLEGTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG
>Mature_397_residues
MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFKELSPDAKGGVRLAKSVADVV
ANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYLSILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAID
PERGVTADDVKKLNAALKLDGDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVL
ELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITKDPA
VKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLEGTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=42.6020408163265, Blast_Score=329, Evalue=2e-90,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=45.5958549222798, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=45.2054794520548, Blast_Score=295, Evalue=4e-80,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=51.8891687657431, Blast_Score=388, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.5569620253165, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=43.4010152284264, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=44.0506329113924, Blast_Score=335, Evalue=5e-93,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.3551637279597, Blast_Score=348, Evalue=5e-96,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=45.6185567010309, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=45.6185567010309, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=45.7583547557841, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=45.7583547557841, Blast_Score=330, Evalue=1e-90,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_RHILO (Q98EC5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105209.1
- ProteinModelPortal:   Q98EC5
- SMR:   Q98EC5
- GeneID:   1227870
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4306
- NMPDR:   fig|266835.1.peg.3313
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- BRENDA:   6.2.1.5
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42032; Mature: 42032

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFK
CCCCHHCCHHHHHHCCCCHHCCCCCEECCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
ELSPDAKGGVRLAKSVADVVANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYL
CCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCEEEEEEECCCCCCHHEEE
SILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAIDPERGVTADDVKKLNAALKLD
EEEEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHEEEEC
GDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVL
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEECCCCEEECCCCCE
ELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
EECCCCCHHHHHHHHCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITKDPAVKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLE
CCCCCHHEEEEEEEEECCCCCCEEHEEHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQGKALLKSFGAPVAEGVPVFKASEAEAAARALPGPLYVVKSQIHAGGRGKGKFK
CCCCHHCCHHHHHHCCCCHHCCCCCEECCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
ELSPDAKGGVRLAKSVADVVANANEMLGHTLVTKQTGPAGKQVNRLYIEDGADIERELYL
CCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCEEEEEEECCCCCCHHEEE
SILVDRSVGRIAFVVSTEGGMDIEAVAHDTPEKVITVAIDPERGVTADDVKKLNAALKLD
EEEEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHEEEEC
GDAAKDGGTLFPILYKAFIEKDMSLLEVNPLIVMKNGRLRVLDAKVSFDNNALFRHPDVL
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEECCCCEEECCCCCE
ELRDTTEEDEKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
EECCCCCHHHHHHHHCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITKDPAVKGILINIFGGIMKCDIIAEGVIAAVKEVGLEVPLVVRLE
CCCCCHHEEEEEEEEECCCCCCEEHEEHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNAELGKKIINDSGLNVVSADDLDDAAKKIVAAVKG
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968