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The map label for this gene is yvrH [H]

Identifier: 13473588

GI number: 13473588

Start: 3380634

End: 3381317

Strand: Direct

Name: yvrH [H]

Synonym: mlr4237

Alternate gene names: 13473588

Gene position: 3380634-3381317 (Clockwise)

Preceding gene: 13473586

Following gene: 13473589

Centisome position: 48.05

GC content: 62.28

Gene sequence:

>684_bases
ATGACTTCACGCACCATCCTAATCGTCGACGACGACGACGACCTGCGCGGCACGCTGGTCGAGCAACTCGCCCTCTACGA
GGAATTCGACGTGCTGCAGGAAGCGACTGCGGCAAAAGGCGTCACCGCGGCACGCGGCGGCCTCATCGACCTGCTCATCA
TGGATGTCGGCCTGCCCGACATGGACGGCCGCGAGGCCGTCAAGATCCTGCGCAAAGGCGGCTACAAGGCGCCCATCATC
ATGCTGACCGGCCACGACACCGATTCGGACACGATTCTGGGTCTCGAGGCCGGCGCCAACGACTATGTGACCAAGCCGTT
CCGCTTCGCGGTTCTGCTGGCGCGCATCCGTGCCCAGCTGCGGCAGCACGAGCAGAGCGAGGACGCCACCTTCTCGGTCG
GCCCCTACACCTTCAAGCCCAGCCAGAAGCTGCTCATCGACCCGCGTGGCGGCAAGGTGCGACTGACGGAGAAGGAAGCC
TCGATCATCAAATATCTCTACCGTGCCGACCAGAAGGTGGTGACCCGCGACGTGCTGCTCGAGGAAGTCTGGGGCTACAA
TTCCGGCGTCACCACGCACACGCTGGAAACCCATGTCTACCGGCTGCGCCAGAAGATCGAGCGCGATCCTTCCAATGCGG
AAATTCTTGTGACAGAAAGCGGTGGCTACAAGCTGGTTCCTTAA

Upstream 100 bases:

>100_bases
CCACGGAACAAATCACTGTGATCGGCTATTGTGTCGGCCAGCTTCCGCATAAATACGCAGCGGTCAACTGAATTTCATTT
TCAAAACAACGGATTGATCC

Downstream 100 bases:

>100_bases
ACATTTCACTATCCAATGAGCAATTCCAGGAAAAGTGTGGGCGGTTTTCCGTCCGGAATTGCGAAAACTAGATGGATGGA
GCGGTCTGGGCGGGACCGCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTSRTILIVDDDDDLRGTLVEQLALYEEFDVLQEATAAKGVTAARGGLIDLLIMDVGLPDMDGREAVKILRKGGYKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFSVGPYTFKPSQKLLIDPRGGKVRLTEKEA
SIIKYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTESGGYKLVP

Sequences:

>Translated_227_residues
MTSRTILIVDDDDDLRGTLVEQLALYEEFDVLQEATAAKGVTAARGGLIDLLIMDVGLPDMDGREAVKILRKGGYKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFSVGPYTFKPSQKLLIDPRGGKVRLTEKEA
SIIKYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTESGGYKLVP
>Mature_226_residues
TSRTILIVDDDDDLRGTLVEQLALYEEFDVLQEATAAKGVTAARGGLIDLLIMDVGLPDMDGREAVKILRKGGYKAPIIM
LTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQLRQHEQSEDATFSVGPYTFKPSQKLLIDPRGGKVRLTEKEAS
IIKYLYRADQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTESGGYKLVP

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.5132743362832, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=33.7719298245614, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082012, Length=177, Percent_Identity=36.1581920903955, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786784, Length=196, Percent_Identity=34.1836734693878, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.304347826087, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=160, Percent_Identity=30, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787375, Length=174, Percent_Identity=31.6091954022989, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=30.1310043668122, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786599, Length=238, Percent_Identity=27.7310924369748, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=34.7619047619048, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787229, Length=203, Percent_Identity=29.5566502463054, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=30.5785123966942, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25307; Mature: 25176

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRTILIVDDDDDLRGTLVEQLALYEEFDVLQEATAAKGVTAARGGLIDLLIMDVGLPD
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCC
MDGREAVKILRKGGYKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFSVGPYTFKPSQKLLIDPRGGKVRLTEKEASIIKYLYRADQKVVTRDVLL
HHCCCCCCCEEEECCEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTESGGYKLVP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TSRTILIVDDDDDLRGTLVEQLALYEEFDVLQEATAAKGVTAARGGLIDLLIMDVGLPD
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCC
MDGREAVKILRKGGYKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRAQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFSVGPYTFKPSQKLLIDPRGGKVRLTEKEASIIKYLYRADQKVVTRDVLL
HHCCCCCCCEEEECCEEECCCCEEEEECCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTESGGYKLVP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]