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The map label for this gene is yegE [H]

Identifier: 13473015

GI number: 13473015

Start: 2814372

End: 2816006

Strand: Reverse

Name: yegE [H]

Synonym: mll3491

Alternate gene names: 13473015

Gene position: 2816006-2814372 (Counterclockwise)

Preceding gene: 13473016

Following gene: 13473007

Centisome position: 40.02

GC content: 65.44

Gene sequence:

>1635_bases
ATGCTCGGCTACAGCCGTGAAGAGATCGAGGCGCTGACCTTTTTCCAGATCACGCACCCTGACGACCTGCATGTCGGGCG
GGAAACCATGGAAGGCGTCAAGGCTAGCACGGTCAACGCCTTCCAGTTCGAGAAGCGTTACCTTAAGAAGGACGGCACAG
CTGTCTGGGCGCACCTCGCCGGCTCCGTCATTCGAGAGGAGAAGAGCGGCCGCCCGCTCTATCTCGTTTCGCAGATCGAG
GACATCGACGCGCGCAAGCAGGCCGAGGCGCGCATCGCCGAGGCCGAAACGCGCTGGAATTTCGCGCTTGCCGGCGCCGG
CCAGGGCGTCTGGGATCTCGACATCCGCAAAGGCGGCACGACCTACTCCTCGACCTGGGTCAAGATGCTGGGTTATGCGG
ATGGCGAACTAGACGGCAACCCGGATCGTTGGCTGACGATGATCCATCCCGACGACCGCGAAACCGTCGCCGAGGCGGAT
CGCGCCCATCTCGACGGCAAGACTGAGTTCTTCGAGGCCGAGTTCAGGATGCGTCACAAGGACGGCCGCTGGATCTGGAT
TCTCGACCGCGGCAAGGCCATCGAGCGCGACGGAGAGGGGCGTCTGGTCAGGGCCATCGGTAGCCTGACCGACATCACCC
GGCGCAAGGAGGCCGAGGAGCGTCTGACCGTATCGGCGGCAATGCTGGCCGACGAGAAAGAGCGGCTCCGGGTAACGCTG
CAGTCGATCGGCGATGCCGTCATCTGCACCGATGCGGCGAACCGAGTCACCTTCATGAATCCGGTTGCCGAGAAGCTGAC
CGGCGTTTCGGCGGAGGCGGCTCTCGGCAAGACGCTCGGCCATGTCTATTGGGCGGTCGACGAGGAAACGGGACACAGGA
TCGGCGTGACACGGCCGGCGATCGGCGCGGAGACGCCCTCCGACAAGAACAGCCGCGCCGTGCTGGTCCGCCGCGACGAC
ACACGCTGCAGCATTCGCCAGGTCGTGTCGCCGATCATGAACGAGCGCAACGAATTCAGTGGTCTGGTCATCGTCTTCCA
GGATTTTACCGACGCGCGCGCCCTGCAGCGCCAGCTTGCCCACGCCGCCGCGCATGATGCGCTGACCGGCCTTGCCAATC
GGTCGAGCTTCATCCGCACCATGGAGGAGCTCGTCGATCAGGCCCGCAAGGATGCCGCCGGGGCTGGCAGCAGCGGCCAT
CAGTTCATGTTCATCGACCTCGACCATTTCAAGCTGGTCAACGACACCGGCGGTCACGCCGCCGGAGACGCCTTGCTGAA
GCGGGTCGCACAGGCCGTGCGTGGCGTACTGAGGCCTGAAGACATTGTCGCGCGCCTGGGCGGCGATGAATTCGCGGTCA
TCCTGAAATCGGGCTCGATCGCCGGCGCCACGATCGCGGCGCGCTCCATCATCGATGCGATAGCGGGATTGAACTTCACC
TGGGATGGCCGGCCGCATGCCATCGGCGCCAGCATCGGTGTGGCGGCGATCAACGCCAATTGCGGCGAGGCGGACGAGAT
CATCGCAAGGGCCGACGCCGCCTGCTATGCCGCCAAGGCGGCCGGCCGCGGATGCGTCTGCGTGGCGCCCGACGACAAGT
CGGAGCCGCCCGCGCCGCTTGCCGCGGCGTCATGA

Upstream 100 bases:

>100_bases
CGAGCAGCGCTTCCGCCGGGCGATGGAAGACTCGGCAATCGGCATCGCCGTCGTCGGCCTCGATGGGCGCATTGTGCAGA
CCAATCCGGCCTTCGCCTCG

Downstream 100 bases:

>100_bases
ACGGACGCGTCAGCGCGTCGGAACGGGGTGCTCGCCGCGATAGTCGTAGAAACCGCGCCCGGTCTTGCGGCCGAGCCAAC
CAGCTTCGACATATTTCACC

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MLGYSREEIEALTFFQITHPDDLHVGRETMEGVKASTVNAFQFEKRYLKKDGTAVWAHLAGSVIREEKSGRPLYLVSQIE
DIDARKQAEARIAEAETRWNFALAGAGQGVWDLDIRKGGTTYSSTWVKMLGYADGELDGNPDRWLTMIHPDDRETVAEAD
RAHLDGKTEFFEAEFRMRHKDGRWIWILDRGKAIERDGEGRLVRAIGSLTDITRRKEAEERLTVSAAMLADEKERLRVTL
QSIGDAVICTDAANRVTFMNPVAEKLTGVSAEAALGKTLGHVYWAVDEETGHRIGVTRPAIGAETPSDKNSRAVLVRRDD
TRCSIRQVVSPIMNERNEFSGLVIVFQDFTDARALQRQLAHAAAHDALTGLANRSSFIRTMEELVDQARKDAAGAGSSGH
QFMFIDLDHFKLVNDTGGHAAGDALLKRVAQAVRGVLRPEDIVARLGGDEFAVILKSGSIAGATIAARSIIDAIAGLNFT
WDGRPHAIGASIGVAAINANCGEADEIIARADAACYAAKAAGRGCVCVAPDDKSEPPAPLAAAS

Sequences:

>Translated_544_residues
MLGYSREEIEALTFFQITHPDDLHVGRETMEGVKASTVNAFQFEKRYLKKDGTAVWAHLAGSVIREEKSGRPLYLVSQIE
DIDARKQAEARIAEAETRWNFALAGAGQGVWDLDIRKGGTTYSSTWVKMLGYADGELDGNPDRWLTMIHPDDRETVAEAD
RAHLDGKTEFFEAEFRMRHKDGRWIWILDRGKAIERDGEGRLVRAIGSLTDITRRKEAEERLTVSAAMLADEKERLRVTL
QSIGDAVICTDAANRVTFMNPVAEKLTGVSAEAALGKTLGHVYWAVDEETGHRIGVTRPAIGAETPSDKNSRAVLVRRDD
TRCSIRQVVSPIMNERNEFSGLVIVFQDFTDARALQRQLAHAAAHDALTGLANRSSFIRTMEELVDQARKDAAGAGSSGH
QFMFIDLDHFKLVNDTGGHAAGDALLKRVAQAVRGVLRPEDIVARLGGDEFAVILKSGSIAGATIAARSIIDAIAGLNFT
WDGRPHAIGASIGVAAINANCGEADEIIARADAACYAAKAAGRGCVCVAPDDKSEPPAPLAAAS
>Mature_544_residues
MLGYSREEIEALTFFQITHPDDLHVGRETMEGVKASTVNAFQFEKRYLKKDGTAVWAHLAGSVIREEKSGRPLYLVSQIE
DIDARKQAEARIAEAETRWNFALAGAGQGVWDLDIRKGGTTYSSTWVKMLGYADGELDGNPDRWLTMIHPDDRETVAEAD
RAHLDGKTEFFEAEFRMRHKDGRWIWILDRGKAIERDGEGRLVRAIGSLTDITRRKEAEERLTVSAAMLADEKERLRVTL
QSIGDAVICTDAANRVTFMNPVAEKLTGVSAEAALGKTLGHVYWAVDEETGHRIGVTRPAIGAETPSDKNSRAVLVRRDD
TRCSIRQVVSPIMNERNEFSGLVIVFQDFTDARALQRQLAHAAAHDALTGLANRSSFIRTMEELVDQARKDAAGAGSSGH
QFMFIDLDHFKLVNDTGGHAAGDALLKRVAQAVRGVLRPEDIVARLGGDEFAVILKSGSIAGATIAARSIIDAIAGLNFT
WDGRPHAIGASIGVAAINANCGEADEIIARADAACYAAKAAGRGCVCVAPDDKSEPPAPLAAAS

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=531, Percent_Identity=36.1581920903955, Blast_Score=321, Evalue=6e-89,
Organism=Escherichia coli, GI1787541, Length=297, Percent_Identity=28.6195286195286, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081881, Length=188, Percent_Identity=35.6382978723404, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787262, Length=195, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1786584, Length=188, Percent_Identity=33.5106382978723, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082007, Length=182, Percent_Identity=35.1648351648352, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081977, Length=200, Percent_Identity=31.5, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693134, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=36.5269461077844, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787802, Length=174, Percent_Identity=28.735632183908, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787816, Length=177, Percent_Identity=32.2033898305085, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=185, Percent_Identity=28.1081081081081, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081974, Length=101, Percent_Identity=40.5940594059406, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 59114; Mature: 59114

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGYSREEIEALTFFQITHPDDLHVGRETMEGVKASTVNAFQFEKRYLKKDGTAVWAHLA
CCCCCHHHHCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GSVIREEKSGRPLYLVSQIEDIDARKQAEARIAEAETRWNFALAGAGQGVWDLDIRKGGT
HHHHHHHCCCCCEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCC
TYSSTWVKMLGYADGELDGNPDRWLTMIHPDDRETVAEADRAHLDGKTEFFEAEFRMRHK
CHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEC
DGRWIWILDRGKAIERDGEGRLVRAIGSLTDITRRKEAEERLTVSAAMLADEKERLRVTL
CCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QSIGDAVICTDAANRVTFMNPVAEKLTGVSAEAALGKTLGHVYWAVDEETGHRIGVTRPA
HHHCCEEEEECCCCCEEEECHHHHHHCCCCHHHHHHHHHCEEEEEEECCCCCEECCCCCC
IGAETPSDKNSRAVLVRRDDTRCSIRQVVSPIMNERNEFSGLVIVFQDFTDARALQRQLA
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHH
HAAAHDALTGLANRSSFIRTMEELVDQARKDAAGAGSSGHQFMFIDLDHFKLVNDTGGHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCH
AGDALLKRVAQAVRGVLRPEDIVARLGGDEFAVILKSGSIAGATIAARSIIDAIAGLNFT
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
WDGRPHAIGASIGVAAINANCGEADEIIARADAACYAAKAAGRGCVCVAPDDKSEPPAPL
ECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
AAAS
CCCC
>Mature Secondary Structure
MLGYSREEIEALTFFQITHPDDLHVGRETMEGVKASTVNAFQFEKRYLKKDGTAVWAHLA
CCCCCHHHHCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GSVIREEKSGRPLYLVSQIEDIDARKQAEARIAEAETRWNFALAGAGQGVWDLDIRKGGT
HHHHHHHCCCCCEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCCC
TYSSTWVKMLGYADGELDGNPDRWLTMIHPDDRETVAEADRAHLDGKTEFFEAEFRMRHK
CHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEC
DGRWIWILDRGKAIERDGEGRLVRAIGSLTDITRRKEAEERLTVSAAMLADEKERLRVTL
CCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QSIGDAVICTDAANRVTFMNPVAEKLTGVSAEAALGKTLGHVYWAVDEETGHRIGVTRPA
HHHCCEEEEECCCCCEEEECHHHHHHCCCCHHHHHHHHHCEEEEEEECCCCCEECCCCCC
IGAETPSDKNSRAVLVRRDDTRCSIRQVVSPIMNERNEFSGLVIVFQDFTDARALQRQLA
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHH
HAAAHDALTGLANRSSFIRTMEELVDQARKDAAGAGSSGHQFMFIDLDHFKLVNDTGGHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCH
AGDALLKRVAQAVRGVLRPEDIVARLGGDEFAVILKSGSIAGATIAARSIIDAIAGLNFT
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
WDGRPHAIGASIGVAAINANCGEADEIIARADAACYAAKAAGRGCVCVAPDDKSEPPAPL
ECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
AAAS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]