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The map label for this gene is prsA [H]

Identifier: 13472995

GI number: 13472995

Start: 2794093

End: 2795004

Strand: Reverse

Name: prsA [H]

Synonym: mll3467

Alternate gene names: 13472995

Gene position: 2795004-2794093 (Counterclockwise)

Preceding gene: 13473003

Following gene: 13472993

Centisome position: 39.72

GC content: 66.01

Gene sequence:

>912_bases
ATGCCCTTGTTGTTCCGCCGTGCGTCGCTTGCCAGCCTTGGTCTGGCCTTCGGCCTGTCGGCTCTTTGCCTGTCGCCCGT
CATGGCGCAGGAGGCCGCTCCTGCTGCTCCGGCCGCACCCGCTGCGGCGCCGGTCGACCCGAATGCCGTGGTCGCCACGG
TCAACGGCCAGCCCCTGACCGAAGCCGACCTGGTGCTTGCCGAAGGCGAGCTGTCGCAGCAATTCGCGCAGTTGCCGCCC
GAACAGCGCCGCGCGGCTGCCCTTTCGGCGGCCATCGAGATCCGCGTCATGGCCGCCAAGGCCGTTACCGACGGTCTCGA
CAAGGATCCCGACTTCCAGCGCCGCATGGCCTTCCTGCAGCAACGCGCGCTGCATGGCGAGATGGTCGAGAAGGGCGTCG
TCAACAAGGTCACCGACGCCGAGATCCGCGCTCGCTACGACCAGGAAATCGCCAACACGCCGCCGGTCAACGAGGTGCAT
GCCCGTCACATCCTCGTGAAGACGAAGGAAGAGGCCGAGGCGATCATCAAGCAGCTCGACGGAGGCGGTGATTTCCAGAA
GCTCGCCAACGAGCACACCAGCGACCCCTCGGGCAAGTCCAATGGCGGCGACCTAGGCTGGTTCGGGCCTGGCCAGATGG
TGCCGGAGTTCGACAAGGCAGCCTTCGCGCTCGAGGTCGGCAAATACACCGAGCAGCCGGTGCAGACGCAGTTCGGCTGG
CATGTCATCAAGCTCGAGGACAAGCGCGCCAAGCAGCCGCCGGCCTTCGACGACGTCAAGGACCAGGCCAAGCAGGCGGT
CATCCGCGACAAGTATTTCGCCCTGGTCAAGTCGTTGCGCGCCGGCGCCAAGGTCGAGATCCCCGACGCCAAGCTGAAGC
AGGCCGTCGATACGATGGAAGCCGGCAAGTAA

Upstream 100 bases:

>100_bases
TGTCAACGCCGCGCTGGCCCTGCCGGTCGCGCCAAATTCCGCCACAATCTGGCTGATTGGAAGCCACCCCTCCTTACAAT
CCTTCACCGGAGTCATCCTT

Downstream 100 bases:

>100_bases
GTCTGAACGATCTTTTCAAAAAGGGCGCGGCAGCCAAGGGTTGCCGCGCCCTTTTTTTTGTTGACCGCCATGCCGTTATC
TGCCGGCTGCTATGCCTTGC

Product: cell binding factor 2 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPLLFRRASLASLGLAFGLSALCLSPVMAQEAAPAAPAAPAAAPVDPNAVVATVNGQPLTEADLVLAEGELSQQFAQLPP
EQRRAAALSAAIEIRVMAAKAVTDGLDKDPDFQRRMAFLQQRALHGEMVEKGVVNKVTDAEIRARYDQEIANTPPVNEVH
ARHILVKTKEEAEAIIKQLDGGGDFQKLANEHTSDPSGKSNGGDLGWFGPGQMVPEFDKAAFALEVGKYTEQPVQTQFGW
HVIKLEDKRAKQPPAFDDVKDQAKQAVIRDKYFALVKSLRAGAKVEIPDAKLKQAVDTMEAGK

Sequences:

>Translated_303_residues
MPLLFRRASLASLGLAFGLSALCLSPVMAQEAAPAAPAAPAAAPVDPNAVVATVNGQPLTEADLVLAEGELSQQFAQLPP
EQRRAAALSAAIEIRVMAAKAVTDGLDKDPDFQRRMAFLQQRALHGEMVEKGVVNKVTDAEIRARYDQEIANTPPVNEVH
ARHILVKTKEEAEAIIKQLDGGGDFQKLANEHTSDPSGKSNGGDLGWFGPGQMVPEFDKAAFALEVGKYTEQPVQTQFGW
HVIKLEDKRAKQPPAFDDVKDQAKQAVIRDKYFALVKSLRAGAKVEIPDAKLKQAVDTMEAGK
>Mature_302_residues
PLLFRRASLASLGLAFGLSALCLSPVMAQEAAPAAPAAPAAAPVDPNAVVATVNGQPLTEADLVLAEGELSQQFAQLPPE
QRRAAALSAAIEIRVMAAKAVTDGLDKDPDFQRRMAFLQQRALHGEMVEKGVVNKVTDAEIRARYDQEIANTPPVNEVHA
RHILVKTKEEAEAIIKQLDGGGDFQKLANEHTSDPSGKSNGGDLGWFGPGQMVPEFDKAAFALEVGKYTEQPVQTQFGWH
VIKLEDKRAKQPPAFDDVKDQAKQAVIRDKYFALVKSLRAGAKVEIPDAKLKQAVDTMEAGK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=98, Percent_Identity=36.734693877551, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790211, Length=85, Percent_Identity=51.7647058823529, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786238, Length=104, Percent_Identity=40.3846153846154, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786645, Length=143, Percent_Identity=30.0699300699301, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537235, Length=96, Percent_Identity=40.625, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356303, Length=98, Percent_Identity=36.734693877551, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32636; Mature: 32504

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLFRRASLASLGLAFGLSALCLSPVMAQEAAPAAPAAPAAAPVDPNAVVATVNGQPLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC
EADLVLAEGELSQQFAQLPPEQRRAAALSAAIEIRVMAAKAVTDGLDKDPDFQRRMAFLQ
HHHEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QRALHGEMVEKGVVNKVTDAEIRARYDQEIANTPPVNEVHARHILVKTKEEAEAIIKQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECHHHHHHHHHHCC
GGGDFQKLANEHTSDPSGKSNGGDLGWFGPGQMVPEFDKAAFALEVGKYTEQPVQTQFGW
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCE
HVIKLEDKRAKQPPAFDDVKDQAKQAVIRDKYFALVKSLRAGAKVEIPDAKLKQAVDTME
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHH
AGK
CCC
>Mature Secondary Structure 
PLLFRRASLASLGLAFGLSALCLSPVMAQEAAPAAPAAPAAAPVDPNAVVATVNGQPLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCC
EADLVLAEGELSQQFAQLPPEQRRAAALSAAIEIRVMAAKAVTDGLDKDPDFQRRMAFLQ
HHHEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QRALHGEMVEKGVVNKVTDAEIRARYDQEIANTPPVNEVHARHILVKTKEEAEAIIKQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECHHHHHHHHHHCC
GGGDFQKLANEHTSDPSGKSNGGDLGWFGPGQMVPEFDKAAFALEVGKYTEQPVQTQFGW
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCE
HVIKLEDKRAKQPPAFDDVKDQAKQAVIRDKYFALVKSLRAGAKVEIPDAKLKQAVDTME
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHH
AGK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA