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The map label for this gene is aatA [H]

Identifier: 13472296

GI number: 13472296

Start: 2058643

End: 2059845

Strand: Direct

Name: aatA [H]

Synonym: mlr2541

Alternate gene names: 13472296

Gene position: 2058643-2059845 (Clockwise)

Preceding gene: 13472291

Following gene: 13472298

Centisome position: 29.26

GC content: 62.93

Gene sequence:

>1203_bases
ATGGCCTTTCTTGCCGACACCCTTTCCCGCGTAAAGCCTTCCGCCACCATCGCGGTGACGCAGAAAGCGCGCGAGCTGAA
AAATGCCGGCCGTGACATTATCGGCCTCGGCGCCGGCGAACCGGATTTCGACACGCCCGACAACATCAAGAATGCGGCGA
TCGAAGCCATCCGCCGTGGCGAAACCAAGTACCCGCCGGTTTCGGGCATCGTGCCGCTGCGCGAGGCGATCGCAAAAAAA
TTCAAGCGTGAGAACAATCTCGACTACAAGCCCGAGCAGACCATTGTCGGCACCGGCGGCAAGCAGATCCTGTTCAATGC
CTTCATGGCGACGCTGAACCCCGGCGACGAGGTCATCATCCCCCGCCCCTACTGGGTCAGCTACCCCGAAATGGTGGCGA
TCTGCGGCGGCACGTCGGTGTTCGCCGACACCTCGATCGAGAATGGCTTCAAGCTGACGGCCGAAGTGCTGGAAAAGGCG
ATCACGCCGAAGACCAAATGGCTGCTGATGAACTCGCCGTCCAACCCGTCGGGCGCGGCCTACACGCAAGCCGAACTGCG
CGCGCTGGCCGACGTGCTGTTGAAGCATCCGCATGTCTGGACGCTGACCGACGACATGTACGAGCACCTGACCTATGGCG
ACTTCGCCTTCAAGACCATCGCCGAGGTCGAGCCGAAGCTCTATGAGCGCACGCTGACCATGAACGGCGTGTCGAAAGCC
TATGCCATGACCGGCTGGCGCATCGGCTATGCCGCGGGTCCCGTCCAGCTGATCAAGGCGATGGACATGATCCAGGGCCA
GCAGACCTCGGGCGCCTGCACCATCGCGCAATGGGCTTCCGTCGAGGCGCTCAACGGCCCGCAGGATTTCATCGCCAGGA
ACAAGGCGATCTTCCAGGGCCGGCGCGACCTCGTCGTCTCGATGCTCAACCAGGCGCGCGGCATCACGTGCCCGTCGCCG
GAAGGCGCCTTCTATGTCTATCCGTCCTGCGCCCAGCTGATCGGCAAGAAGACCAAGGCCGGCAAGGTGATCGACACCGA
CGAGGCCTTCTGTTCGGAACTGCTCGAGGCGGAAGGTGTGGCGGTGGTGTTCGGCTCTGCCTTCGGCCTCGGCCCCAACT
TCCGCATCTCCTATGCCACGTCGGATGCACTGCTGGAGGAAGCCTGCACGCGCATCCAGCGCTTCACGGCATCGCTGACC
TGA

Upstream 100 bases:

>100_bases
GATCAGCCGACAATGCTTGCACTGAGCGAAATCATGCGACATGAGAAGCGCCGCGGCCGCTCCTGGCCGCGCCGATCTTC
TCAAGGAGAGATATTTGGTC

Downstream 100 bases:

>100_bases
CCGGATCGATCTGACGACAACAGAAACCCGGCGCAGTCATCGCCGGGTTTTTTGTTGGAGGCGGGGCACCTTACGCCTGC
TGCCTTGCTTGCCTGGCCGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAFLADTLSRVKPSATIAVTQKARELKNAGRDIIGLGAGEPDFDTPDNIKNAAIEAIRRGETKYPPVSGIVPLREAIAKK
FKRENNLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIPRPYWVSYPEMVAICGGTSVFADTSIENGFKLTAEVLEKA
ITPKTKWLLMNSPSNPSGAAYTQAELRALADVLLKHPHVWTLTDDMYEHLTYGDFAFKTIAEVEPKLYERTLTMNGVSKA
YAMTGWRIGYAAGPVQLIKAMDMIQGQQTSGACTIAQWASVEALNGPQDFIARNKAIFQGRRDLVVSMLNQARGITCPSP
EGAFYVYPSCAQLIGKKTKAGKVIDTDEAFCSELLEAEGVAVVFGSAFGLGPNFRISYATSDALLEEACTRIQRFTASLT

Sequences:

>Translated_400_residues
MAFLADTLSRVKPSATIAVTQKARELKNAGRDIIGLGAGEPDFDTPDNIKNAAIEAIRRGETKYPPVSGIVPLREAIAKK
FKRENNLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIPRPYWVSYPEMVAICGGTSVFADTSIENGFKLTAEVLEKA
ITPKTKWLLMNSPSNPSGAAYTQAELRALADVLLKHPHVWTLTDDMYEHLTYGDFAFKTIAEVEPKLYERTLTMNGVSKA
YAMTGWRIGYAAGPVQLIKAMDMIQGQQTSGACTIAQWASVEALNGPQDFIARNKAIFQGRRDLVVSMLNQARGITCPSP
EGAFYVYPSCAQLIGKKTKAGKVIDTDEAFCSELLEAEGVAVVFGSAFGLGPNFRISYATSDALLEEACTRIQRFTASLT
>Mature_399_residues
AFLADTLSRVKPSATIAVTQKARELKNAGRDIIGLGAGEPDFDTPDNIKNAAIEAIRRGETKYPPVSGIVPLREAIAKKF
KRENNLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIPRPYWVSYPEMVAICGGTSVFADTSIENGFKLTAEVLEKAI
TPKTKWLLMNSPSNPSGAAYTQAELRALADVLLKHPHVWTLTDDMYEHLTYGDFAFKTIAEVEPKLYERTLTMNGVSKAY
AMTGWRIGYAAGPVQLIKAMDMIQGQQTSGACTIAQWASVEALNGPQDFIARNKAIFQGRRDLVVSMLNQARGITCPSPE
GAFYVYPSCAQLIGKKTKAGKVIDTDEAFCSELLEAEGVAVVFGSAFGLGPNFRISYATSDALLEEACTRIQRFTASLT

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=402, Percent_Identity=26.1194029850746, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI169881279, Length=402, Percent_Identity=26.1194029850746, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=27.1875, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=27.1875, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4507369, Length=398, Percent_Identity=24.6231155778894, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=23.2911392405063, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786816, Length=371, Percent_Identity=26.9541778975741, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=26.7676767676768, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=30.8988764044944, Blast_Score=121, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=363, Percent_Identity=27.2727272727273, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=363, Percent_Identity=27.2727272727273, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=23.6979166666667, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=256, Percent_Identity=27.734375, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=26.9521410579345, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=249, Percent_Identity=24.8995983935743, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=361, Percent_Identity=24.9307479224377, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646114, Length=361, Percent_Identity=24.9307479224377, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573067, Length=361, Percent_Identity=24.9307479224377, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573065, Length=361, Percent_Identity=24.9307479224377, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI18859735, Length=380, Percent_Identity=23.9473684210526, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24641770, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641760, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641768, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641766, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641764, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551451, Length=375, Percent_Identity=26.4, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43542; Mature: 43411

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLADTLSRVKPSATIAVTQKARELKNAGRDIIGLGAGEPDFDTPDNIKNAAIEAIRRG
CCHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
ETKYPPVSGIVPLREAIAKKFKRENNLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVII
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
PRPYWVSYPEMVAICGGTSVFADTSIENGFKLTAEVLEKAITPKTKWLLMNSPSNPSGAA
CCCCCCCCHHHEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
YTQAELRALADVLLKHPHVWTLTDDMYEHLTYGDFAFKTIAEVEPKLYERTLTMNGVSKA
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCHHH
YAMTGWRIGYAAGPVQLIKAMDMIQGQQTSGACTIAQWASVEALNGPQDFIARNKAIFQG
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHC
RRDLVVSMLNQARGITCPSPEGAFYVYPSCAQLIGKKTKAGKVIDTDEAFCSELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCE
AVVFGSAFGLGPNFRISYATSDALLEEACTRIQRFTASLT
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFLADTLSRVKPSATIAVTQKARELKNAGRDIIGLGAGEPDFDTPDNIKNAAIEAIRRG
CHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
ETKYPPVSGIVPLREAIAKKFKRENNLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVII
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
PRPYWVSYPEMVAICGGTSVFADTSIENGFKLTAEVLEKAITPKTKWLLMNSPSNPSGAA
CCCCCCCCHHHEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCH
YTQAELRALADVLLKHPHVWTLTDDMYEHLTYGDFAFKTIAEVEPKLYERTLTMNGVSKA
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCHHH
YAMTGWRIGYAAGPVQLIKAMDMIQGQQTSGACTIAQWASVEALNGPQDFIARNKAIFQG
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCCEEEHHHCCCCCCCCCHHHHHHHHHHHHC
RRDLVVSMLNQARGITCPSPEGAFYVYPSCAQLIGKKTKAGKVIDTDEAFCSELLEAEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCE
AVVFGSAFGLGPNFRISYATSDALLEEACTRIQRFTASLT
EEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]