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The map label for this gene is nlpI [C]

Identifier: 13472042

GI number: 13472042

Start: 1786852

End: 1788828

Strand: Reverse

Name: nlpI [C]

Synonym: mll2209

Alternate gene names: 13472042

Gene position: 1788828-1786852 (Counterclockwise)

Preceding gene: 13472043

Following gene: 13472041

Centisome position: 25.42

GC content: 62.27

Gene sequence:

>1977_bases
ATGCTTCATGGATTTTTGCGATTGGCTGCGGGGGCAGGGCGGTCTCTGGCTGTTCCTGCGATCCTGCTCGCACTCGGCGC
TCCCGCCCAGGCTGGAAGCCTTCTGGAGGATTGCGCGAACGACAAGCTTACACCGCCCAACCGGATCGTCGCCTGCACCA
ATGTGCTGGAGGACAAGGCCGCTTCGGCGAGCGACCAGGCCGTTGCCTATTTCAACCGCGCCAACGCGCTGGACAGGAAC
GGCGAGTTCGACCGTGCCATCGCCGACTACGACAAGGCGATCGCCTTCAATCCCAAAGACGCCGAGGCTTTCAACAACCG
GGGGCTGATCTGGGGCCACAAGAAGGATTTTGACCGCGCCCTGGCCGACTATGACAAGGCGATCGAGCTCAATCCGCAGA
TTGCCATTGCCTATGCCAACCGCGGCCTGATCTGGAACGATATAAAGCACGACTATGTGAAGGCCATCGCCGATTTCGAC
AAGGCGATCCGCCTCGATCCGGAAAACAACGGCCTGTACAATCTTCGCGGCAATGCCTATCTGCGCAAGGGCGACTACGA
CCAGGCCATCACCAGCTACAGCCAGGCGATCTTTCTCGACTCGCAAGATCCGAACCAGTATTTCAACCTCGGGCTGGCCT
GGACCACCAAGGGCAATCTGGAGCGCGCCATAGCGGATTACAGCCAGGCGATCAGCCTCGATGCGAACCATGCCGAAGCC
TATCGCTGGCGCGCCGACGCCTGGGTGAAGCGAGGCGATACGGACCAGGCCCTGTCGGACTATACCGAGGCGATCAGGCT
CGATCCCGGCGACGCCGAGACGTTCCGCAACCGCGCCAGGATCTGGGAGCGCAAACGGGACTACGACCGCGCCATCGCGG
ATTACGATCAGGCGATCGCCTTCGCTCCGAACGACGCGGTGGCCTACAATGGCCGTGGCTGGATGTGGTCGCTGAAACAT
GAGACCGACCGCGCCATCGTTGACTATGTCAAGGCAACCGCCTTCGATCCGAACTATGTGCTGGCTTACGACAATCTGGG
CCTGGCGTGGTGGGATAAGGGCGACCTTGACCGTGCCATATCGGCCTTCGACCAGGCCGTGATCGTCGATCCGAAATATG
CGCCGGCCTATAATGACAGGGGGCTCGCGCGGATGGACAAGAACCAGTACGACCTTGCCATCGCCGACTACAATATGGCG
ATCCTGATCGACGCCGGATTTGTCAGCGCTTACCGCAACCGGGGCAATGCCTGGAACCGGAAGGGCCAGTTCGACTACGC
CATAGCCGACTTCGACCAGGCGATCGATCACGACCCGGACGATGCCGACGCCTATGTCGGCCGGGGCCGCAGCAGGATCT
ACAAGGCAGACTATACTAAGGCCATCGCCGATCTGGATCAGGCGATCCGCATCGGACCCAAAAGCGCTAGAGCCCACGAC
ACGCGCGGCCTGGCGATGGTCTACAAGGCCGACTATGCCGGCGCGCTGGCCGATTATGATGAAGCGATCCGCCTCAGCCC
GAAAAATGCCAGCGCCTACCGGAACCGGGGCATTGCCAGCTTCTATTTCGGCCCGCCCGCCAAGGCGCAGGCCGACTTCG
AGCAGGCGGCCGCGATCAAGCCCGGGGATTCCTATCATGCGATCTGGCTCGATCTCGCGCGGCGGCGCAACGGGCAGCCC
TCCATCCTTGTGGATGCCAAGCTCGACATGACGAGATGGCCGGCGGCGGTGGTTCGCCTGCTGCTTGGCCAGCAGACGCC
GGAGGCCACGCTCCTCGCCGCCGACAATCCGGATGCGACGAAGAAAAGCGAGCAGCTCTGCGAGGCGAATTTCTACGTCG
CGGAGTTCCAGCGGCTGCAACACCATGATGAGGAGGCGTTGCGGCTCTACCGGCTGGCCCTTGGCGGCTGTCCTCGCGAT
TTCATCGAGTACACCGCCGCCACCAGCGCACTGCGCGTGATGGGCAAGGCGCCATGA

Upstream 100 bases:

>100_bases
GATTTCTTTTCCACGGTGACTTGCGGCGACCAGGAATTTGCCTGATCAAGTCGGCATAAGGCCAACAACCAGTAATTGCG
ATCCAGATTCCGCTGACATG

Downstream 100 bases:

>100_bases
GGTTCCACTGGCGTTCCGGCCTGACTGCTGTGGCAGTGATGTTCGCGCTCGGCACTGCGGCGACGGCTGCCGGCAAGGAC
CATGCCGACTGTGTCAATGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MLHGFLRLAAGAGRSLAVPAILLALGAPAQAGSLLEDCANDKLTPPNRIVACTNVLEDKAASASDQAVAYFNRANALDRN
GEFDRAIADYDKAIAFNPKDAEAFNNRGLIWGHKKDFDRALADYDKAIELNPQIAIAYANRGLIWNDIKHDYVKAIADFD
KAIRLDPENNGLYNLRGNAYLRKGDYDQAITSYSQAIFLDSQDPNQYFNLGLAWTTKGNLERAIADYSQAISLDANHAEA
YRWRADAWVKRGDTDQALSDYTEAIRLDPGDAETFRNRARIWERKRDYDRAIADYDQAIAFAPNDAVAYNGRGWMWSLKH
ETDRAIVDYVKATAFDPNYVLAYDNLGLAWWDKGDLDRAISAFDQAVIVDPKYAPAYNDRGLARMDKNQYDLAIADYNMA
ILIDAGFVSAYRNRGNAWNRKGQFDYAIADFDQAIDHDPDDADAYVGRGRSRIYKADYTKAIADLDQAIRIGPKSARAHD
TRGLAMVYKADYAGALADYDEAIRLSPKNASAYRNRGIASFYFGPPAKAQADFEQAAAIKPGDSYHAIWLDLARRRNGQP
SILVDAKLDMTRWPAAVVRLLLGQQTPEATLLAADNPDATKKSEQLCEANFYVAEFQRLQHHDEEALRLYRLALGGCPRD
FIEYTAATSALRVMGKAP

Sequences:

>Translated_658_residues
MLHGFLRLAAGAGRSLAVPAILLALGAPAQAGSLLEDCANDKLTPPNRIVACTNVLEDKAASASDQAVAYFNRANALDRN
GEFDRAIADYDKAIAFNPKDAEAFNNRGLIWGHKKDFDRALADYDKAIELNPQIAIAYANRGLIWNDIKHDYVKAIADFD
KAIRLDPENNGLYNLRGNAYLRKGDYDQAITSYSQAIFLDSQDPNQYFNLGLAWTTKGNLERAIADYSQAISLDANHAEA
YRWRADAWVKRGDTDQALSDYTEAIRLDPGDAETFRNRARIWERKRDYDRAIADYDQAIAFAPNDAVAYNGRGWMWSLKH
ETDRAIVDYVKATAFDPNYVLAYDNLGLAWWDKGDLDRAISAFDQAVIVDPKYAPAYNDRGLARMDKNQYDLAIADYNMA
ILIDAGFVSAYRNRGNAWNRKGQFDYAIADFDQAIDHDPDDADAYVGRGRSRIYKADYTKAIADLDQAIRIGPKSARAHD
TRGLAMVYKADYAGALADYDEAIRLSPKNASAYRNRGIASFYFGPPAKAQADFEQAAAIKPGDSYHAIWLDLARRRNGQP
SILVDAKLDMTRWPAAVVRLLLGQQTPEATLLAADNPDATKKSEQLCEANFYVAEFQRLQHHDEEALRLYRLALGGCPRD
FIEYTAATSALRVMGKAP
>Mature_658_residues
MLHGFLRLAAGAGRSLAVPAILLALGAPAQAGSLLEDCANDKLTPPNRIVACTNVLEDKAASASDQAVAYFNRANALDRN
GEFDRAIADYDKAIAFNPKDAEAFNNRGLIWGHKKDFDRALADYDKAIELNPQIAIAYANRGLIWNDIKHDYVKAIADFD
KAIRLDPENNGLYNLRGNAYLRKGDYDQAITSYSQAIFLDSQDPNQYFNLGLAWTTKGNLERAIADYSQAISLDANHAEA
YRWRADAWVKRGDTDQALSDYTEAIRLDPGDAETFRNRARIWERKRDYDRAIADYDQAIAFAPNDAVAYNGRGWMWSLKH
ETDRAIVDYVKATAFDPNYVLAYDNLGLAWWDKGDLDRAISAFDQAVIVDPKYAPAYNDRGLARMDKNQYDLAIADYNMA
ILIDAGFVSAYRNRGNAWNRKGQFDYAIADFDQAIDHDPDDADAYVGRGRSRIYKADYTKAIADLDQAIRIGPKSARAHD
TRGLAMVYKADYAGALADYDEAIRLSPKNASAYRNRGIASFYFGPPAKAQADFEQAAAIKPGDSYHAIWLDLARRRNGQP
SILVDAKLDMTRWPAAVVRLLLGQQTPEATLLAADNPDATKKSEQLCEANFYVAEFQRLQHHDEEALRLYRLALGGCPRD
FIEYTAATSALRVMGKAP

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=407, Percent_Identity=28.009828009828, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI32307148, Length=407, Percent_Identity=28.009828009828, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI310123097, Length=385, Percent_Identity=25.7142857142857, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310131789, Length=385, Percent_Identity=25.7142857142857, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI310110582, Length=385, Percent_Identity=25.7142857142857, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI170784867, Length=261, Percent_Identity=22.9885057471264, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI83415184, Length=380, Percent_Identity=23.4210526315789, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI301336134, Length=380, Percent_Identity=23.4210526315789, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI5803181, Length=252, Percent_Identity=25.7936507936508, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI225735593, Length=282, Percent_Identity=22.3404255319149, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI225735591, Length=285, Percent_Identity=22.1052631578947, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI167466175, Length=189, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI167466177, Length=189, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI296531396, Length=153, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI262206280, Length=332, Percent_Identity=23.4939759036145, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI225735595, Length=224, Percent_Identity=25.4464285714286, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI5453980, Length=304, Percent_Identity=22.0394736842105, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI54607135, Length=286, Percent_Identity=24.1258741258741, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1789554, Length=226, Percent_Identity=26.9911504424779, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532690, Length=406, Percent_Identity=28.0788177339901, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI115532692, Length=394, Percent_Identity=28.6802030456853, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17563052, Length=269, Percent_Identity=25.2788104089219, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319387, Length=278, Percent_Identity=24.4604316546763, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17647755, Length=395, Percent_Identity=27.3417721518987, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24585827, Length=395, Percent_Identity=27.3417721518987, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24585829, Length=395, Percent_Identity=27.3417721518987, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17137540, Length=225, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864228, Length=111, Percent_Identity=34.2342342342342, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647123, Length=251, Percent_Identity=25.4980079681275, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24583797, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583795, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583793, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076610, Length=363, Percent_Identity=23.4159779614325, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI19920486, Length=363, Percent_Identity=23.4159779614325, Blast_Score=66, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 73393; Mature: 73393

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHGFLRLAAGAGRSLAVPAILLALGAPAQAGSLLEDCANDKLTPPNRIVACTNVLEDKA
CCCHHEEHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHC
ASASDQAVAYFNRANALDRNGEFDRAIADYDKAIAFNPKDAEAFNNRGLIWGHKKDFDRA
CCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCEEEECCCHHHHHCCCCEEECCCHHHHHH
LADYDKAIELNPQIAIAYANRGLIWNDIKHDYVKAIADFDKAIRLDPENNGLYNLRGNAY
HHHCCCEEECCCCEEEEEECCCCEECHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCEE
LRKGDYDQAITSYSQAIFLDSQDPNQYFNLGLAWTTKGNLERAIADYSQAISLDANHAEA
EECCCHHHHHHHCCCEEEEECCCCCHHEEEEEEEECCCCHHHHHHHHHHHEECCCCCHHH
YRWRADAWVKRGDTDQALSDYTEAIRLDPGDAETFRNRARIWERKRDYDRAIADYDQAIA
HEEEHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FAPNDAVAYNGRGWMWSLKHETDRAIVDYVKATAFDPNYVLAYDNLGLAWWDKGDLDRAI
ECCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCHHHHH
SAFDQAVIVDPKYAPAYNDRGLARMDKNQYDLAIADYNMAILIDAGFVSAYRNRGNAWNR
HHHCCEEEECCCCCCCCCCCCCHHCCCCCCEEEEECCCEEEEEECHHHHHHHCCCCCCCC
KGQFDYAIADFDQAIDHDPDDADAYVGRGRSRIYKADYTKAIADLDQAIRIGPKSARAHD
CCCCEEEHHHHHHHHCCCCCCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCCCC
TRGLAMVYKADYAGALADYDEAIRLSPKNASAYRNRGIASFYFGPPAKAQADFEQAAAIK
CCCEEEEEECCCCCCHHCCCHHEEECCCCCHHHHCCCCEEEECCCCCCCCCCHHHHCCCC
PGDSYHAIWLDLARRRNGQPSILVDAKLDMTRWPAAVVRLLLGQQTPEATLLAADNPDAT
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
KKSEQLCEANFYVAEFQRLQHHDEEALRLYRLALGGCPRDFIEYTAATSALRVMGKAP
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLHGFLRLAAGAGRSLAVPAILLALGAPAQAGSLLEDCANDKLTPPNRIVACTNVLEDKA
CCCHHEEHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHC
ASASDQAVAYFNRANALDRNGEFDRAIADYDKAIAFNPKDAEAFNNRGLIWGHKKDFDRA
CCCCCCEEEEEHHCCCCCCCCCHHHHHHHHCCEEEECCCHHHHHCCCCEEECCCHHHHHH
LADYDKAIELNPQIAIAYANRGLIWNDIKHDYVKAIADFDKAIRLDPENNGLYNLRGNAY
HHHCCCEEECCCCEEEEEECCCCEECHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCEE
LRKGDYDQAITSYSQAIFLDSQDPNQYFNLGLAWTTKGNLERAIADYSQAISLDANHAEA
EECCCHHHHHHHCCCEEEEECCCCCHHEEEEEEEECCCCHHHHHHHHHHHEECCCCCHHH
YRWRADAWVKRGDTDQALSDYTEAIRLDPGDAETFRNRARIWERKRDYDRAIADYDQAIA
HEEEHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FAPNDAVAYNGRGWMWSLKHETDRAIVDYVKATAFDPNYVLAYDNLGLAWWDKGDLDRAI
ECCCCCEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCHHHHH
SAFDQAVIVDPKYAPAYNDRGLARMDKNQYDLAIADYNMAILIDAGFVSAYRNRGNAWNR
HHHCCEEEECCCCCCCCCCCCCHHCCCCCCEEEEECCCEEEEEECHHHHHHHCCCCCCCC
KGQFDYAIADFDQAIDHDPDDADAYVGRGRSRIYKADYTKAIADLDQAIRIGPKSARAHD
CCCCEEEHHHHHHHHCCCCCCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCCCC
TRGLAMVYKADYAGALADYDEAIRLSPKNASAYRNRGIASFYFGPPAKAQADFEQAAAIK
CCCEEEEEECCCCCCHHCCCHHEEECCCCCHHHHCCCCEEEECCCCCCCCCCHHHHCCCC
PGDSYHAIWLDLARRRNGQPSILVDAKLDMTRWPAAVVRLLLGQQTPEATLLAADNPDAT
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
KKSEQLCEANFYVAEFQRLQHHDEEALRLYRLALGGCPRDFIEYTAATSALRVMGKAP
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]