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The map label for this gene is nlpI [C]

Identifier: 13472041

GI number: 13472041

Start: 1785200

End: 1786855

Strand: Reverse

Name: nlpI [C]

Synonym: mll2208

Alternate gene names: 13472041

Gene position: 1786855-1785200 (Counterclockwise)

Preceding gene: 13472042

Following gene: 13472040

Centisome position: 25.4

GC content: 60.93

Gene sequence:

>1656_bases
ATGAGGTTCCACTGGCGTTCCGGCCTGACTGCTGTGGCAGTGATGTTCGCGCTCGGCACTGCGGCGACGGCTGCCGGCAA
GGACCATGCCGACTGTGTCAATGAAGGGGTGGAGGCTGCCCACAAGATTGCCGCTTGCACGGCAATCATCGAAGACAAGG
CGGAAGCTTCGGACAACCGCGCCGCGGCCTATTTCAATCGCGCCGGCGCTCTCATCAGGAGAGGCGACAACGACGATGCG
TTCGCCGACTACGACAAGGCGATCGGCATCAACCCGGAGTTGTCGGCCGCCTACTATAACAACGGCATCATCCTGGTGCT
CAAGGGCGACTATGACCGGGCGATAACCTATCTGGACCAGGCAATCTTCCTCGATCCGGACAACGCCGAATTCTACTACA
ACAGAGGCGTTGCCTGGTCCTACAAGGGCAATGACGAGCGTGCCATCGCCGACTACGACGCCGCGATCAAGCTCAATCCC
GGAGATGCCAGGGCCTATCACAACCGGGGCCTGAACTGGGCACGGAAAGGCGATAAGGAGCGCGCCATAGCCGACTACAG
CCAGGCCATCTCGCTCGATCCAAAGAATGCCAGCTCATACAACAACCGGGGCGACGCCTGGGACAGCAAGGGCGACGATG
ATCGCGCGATGGCCGACTACAACCAGGTGATCATTCTCGATACGAAAAACGCCCATGCCTACTATCGTCGTGGCCTGATC
TGGTCGCGCAAGGGTGACGATAGCAGGGCCATCGCGGACTATAGCCAGGTGATCAGCCTCGATCCGACAGACCCCAGCAT
CCGCTACAACAAAGGTCTGGCGTGGTTGCGCAAGGGCGACGGCGATCGCGCGATCGCCGATTTCGACGAGGCGATCCGCC
TCGATCCCAAGATGGCCGCAGCCTACTACGACAGGGGCACCGAATGGCTCAGAAAGGGCGACAGGGACCGCGCCATCACC
GACTATAGCGAGGTCATCACGCTCGAACCGACAAACGCCATGGCGCTGAACGATCGGGGTTTCGTCCTGAACGAGCTGGG
TGAATACGAGCGTGCGCTTGCCGATCTCAACCGCGCGATCGGTCTCGATCCGAAGCAGGCAAAAATATACAGCAACCGGG
CGATCGCCCGGGCGGCAAAAGGCGATTTCGCCCCAGCCCTGGCTGACTACAACCAGGCGATCGCGCTCGATCCGAACTTT
CCCAACGCTTATGCGGGCCGGGGCTTCGTGAATTTCTATTCCGGAATGCTGGCAAAGGCAGAGCCCGATTTTGCCAAGGC
GGCGGCGCTTGCGCCCGACAATGCCTATTTGGCGATCTGGCTCGACATCATCGACCGGCGCAGTGGCGGCACCAGTCATT
TGCGGGAAGCAATTGCCAAGCTCGACATGTCGAAGTGGCCTGCGCCGGTGATCAAGATGCTGCTGGGGCAAAAGACATCC
GCCGAGACCCTTGCCGATGCCGGCACCGGAGACTCCGCGCAAACAAGCGGGCAAGTGTGCGAGGCCAATTTCTACACCGC
AGAACTCGACCGGTTGCAGGCCCGCAACGAAGAAGCCGTGCGGCTTTACCGTCTCGCCGCCAGGACCTGCCCCAAGGGTT
ACATCGAATATCGTGGCGCCGTTGCCGGCCTGCGCTCGCTGGGTATGCTGCCATGA

Upstream 100 bases:

>100_bases
AGGCGTTGCGGCTCTACCGGCTGGCCCTTGGCGGCTGTCCTCGCGATTTCATCGAGTACACCGCCGCCACCAGCGCACTG
CGCGTGATGGGCAAGGCGCC

Downstream 100 bases:

>100_bases
TGCCTAGACTAAGTGCGCTGGTTGCGCTCTGTGTTCCTGCGGCCGCCGAGGACAGCGAAGATTGAGGACAATGGCAGATC
ATCTCGTCGGCGAGTGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRFHWRSGLTAVAVMFALGTAATAAGKDHADCVNEGVEAAHKIAACTAIIEDKAEASDNRAAAYFNRAGALIRRGDNDDA
FADYDKAIGINPELSAAYYNNGIILVLKGDYDRAITYLDQAIFLDPDNAEFYYNRGVAWSYKGNDERAIADYDAAIKLNP
GDARAYHNRGLNWARKGDKERAIADYSQAISLDPKNASSYNNRGDAWDSKGDDDRAMADYNQVIILDTKNAHAYYRRGLI
WSRKGDDSRAIADYSQVISLDPTDPSIRYNKGLAWLRKGDGDRAIADFDEAIRLDPKMAAAYYDRGTEWLRKGDRDRAIT
DYSEVITLEPTNAMALNDRGFVLNELGEYERALADLNRAIGLDPKQAKIYSNRAIARAAKGDFAPALADYNQAIALDPNF
PNAYAGRGFVNFYSGMLAKAEPDFAKAAALAPDNAYLAIWLDIIDRRSGGTSHLREAIAKLDMSKWPAPVIKMLLGQKTS
AETLADAGTGDSAQTSGQVCEANFYTAELDRLQARNEEAVRLYRLAARTCPKGYIEYRGAVAGLRSLGMLP

Sequences:

>Translated_551_residues
MRFHWRSGLTAVAVMFALGTAATAAGKDHADCVNEGVEAAHKIAACTAIIEDKAEASDNRAAAYFNRAGALIRRGDNDDA
FADYDKAIGINPELSAAYYNNGIILVLKGDYDRAITYLDQAIFLDPDNAEFYYNRGVAWSYKGNDERAIADYDAAIKLNP
GDARAYHNRGLNWARKGDKERAIADYSQAISLDPKNASSYNNRGDAWDSKGDDDRAMADYNQVIILDTKNAHAYYRRGLI
WSRKGDDSRAIADYSQVISLDPTDPSIRYNKGLAWLRKGDGDRAIADFDEAIRLDPKMAAAYYDRGTEWLRKGDRDRAIT
DYSEVITLEPTNAMALNDRGFVLNELGEYERALADLNRAIGLDPKQAKIYSNRAIARAAKGDFAPALADYNQAIALDPNF
PNAYAGRGFVNFYSGMLAKAEPDFAKAAALAPDNAYLAIWLDIIDRRSGGTSHLREAIAKLDMSKWPAPVIKMLLGQKTS
AETLADAGTGDSAQTSGQVCEANFYTAELDRLQARNEEAVRLYRLAARTCPKGYIEYRGAVAGLRSLGMLP
>Mature_551_residues
MRFHWRSGLTAVAVMFALGTAATAAGKDHADCVNEGVEAAHKIAACTAIIEDKAEASDNRAAAYFNRAGALIRRGDNDDA
FADYDKAIGINPELSAAYYNNGIILVLKGDYDRAITYLDQAIFLDPDNAEFYYNRGVAWSYKGNDERAIADYDAAIKLNP
GDARAYHNRGLNWARKGDKERAIADYSQAISLDPKNASSYNNRGDAWDSKGDDDRAMADYNQVIILDTKNAHAYYRRGLI
WSRKGDDSRAIADYSQVISLDPTDPSIRYNKGLAWLRKGDGDRAIADFDEAIRLDPKMAAAYYDRGTEWLRKGDRDRAIT
DYSEVITLEPTNAMALNDRGFVLNELGEYERALADLNRAIGLDPKQAKIYSNRAIARAAKGDFAPALADYNQAIALDPNF
PNAYAGRGFVNFYSGMLAKAEPDFAKAAALAPDNAYLAIWLDIIDRRSGGTSHLREAIAKLDMSKWPAPVIKMLLGQKTS
AETLADAGTGDSAQTSGQVCEANFYTAELDRLQARNEEAVRLYRLAARTCPKGYIEYRGAVAGLRSLGMLP

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=344, Percent_Identity=29.9418604651163, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI32307148, Length=344, Percent_Identity=29.9418604651163, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI310123097, Length=338, Percent_Identity=26.6272189349112, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI310131789, Length=338, Percent_Identity=26.6272189349112, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI310110582, Length=338, Percent_Identity=26.6272189349112, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI170784867, Length=352, Percent_Identity=23.5795454545455, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI301336134, Length=344, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI83415184, Length=344, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI5803181, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI262206280, Length=315, Percent_Identity=23.1746031746032, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI167466175, Length=348, Percent_Identity=21.551724137931, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI167466177, Length=348, Percent_Identity=21.551724137931, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI7662078, Length=288, Percent_Identity=24.3055555555556, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI296531396, Length=232, Percent_Identity=23.7068965517241, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI224809432, Length=456, Percent_Identity=20.1754385964912, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI225735593, Length=260, Percent_Identity=24.2307692307692, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI225735591, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1789554, Length=222, Percent_Identity=23.4234234234234, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532692, Length=345, Percent_Identity=30.4347826086957, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI115532690, Length=345, Percent_Identity=30.4347826086957, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17563052, Length=239, Percent_Identity=23.8493723849372, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551190, Length=343, Percent_Identity=24.198250728863, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319387, Length=196, Percent_Identity=25.5102040816327, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17647755, Length=379, Percent_Identity=27.4406332453826, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24585827, Length=379, Percent_Identity=27.4406332453826, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24585829, Length=379, Percent_Identity=27.4406332453826, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647123, Length=318, Percent_Identity=22.0125786163522, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137540, Length=393, Percent_Identity=22.1374045801527, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076610, Length=373, Percent_Identity=24.6648793565684, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920486, Length=373, Percent_Identity=24.6648793565684, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24659892, Length=189, Percent_Identity=24.8677248677249, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 60603; Mature: 60603

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHWRSGLTAVAVMFALGTAATAAGKDHADCVNEGVEAAHKIAACTAIIEDKAEASDNR
CCEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AAAYFNRAGALIRRGDNDDAFADYDKAIGINPELSAAYYNNGIILVLKGDYDRAITYLDQ
HHHHHHHCCHHEECCCCCCCHHHHHHHCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHH
AIFLDPDNAEFYYNRGVAWSYKGNDERAIADYDAAIKLNPGDARAYHNRGLNWARKGDKE
EEEECCCCCCEEEECCEEEEECCCCCCEEECCCCEEEECCCCHHHHHHCCCCHHHCCCCH
RAIADYSQAISLDPKNASSYNNRGDAWDSKGDDDRAMADYNQVIILDTKNAHAYYRRGLI
HHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCHHHHHCCEE
WSRKGDDSRAIADYSQVISLDPTDPSIRYNKGLAWLRKGDGDRAIADFDEAIRLDPKMAA
EECCCCCCHHHHHHHHEEEECCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHCCHHHHH
AYYDRGTEWLRKGDRDRAITDYSEVITLEPTNAMALNDRGFVLNELGEYERALADLNRAI
HHHHCCHHHHHCCCCCCEECCHHHEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
GLDPKQAKIYSNRAIARAAKGDFAPALADYNQAIALDPNFPNAYAGRGFVNFYSGMLAKA
CCCCHHHHHHCCHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCHHCCC
EPDFAKAAALAPDNAYLAIWLDIIDRRSGGTSHLREAIAKLDMSKWPAPVIKMLLGQKTS
CCCHHHHHCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
AETLADAGTGDSAQTSGQVCEANFYTAELDRLQARNEEAVRLYRLAARTCPKGYIEYRGA
HHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
VAGLRSLGMLP
HHHHHHHCCCC
>Mature Secondary Structure
MRFHWRSGLTAVAVMFALGTAATAAGKDHADCVNEGVEAAHKIAACTAIIEDKAEASDNR
CCEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AAAYFNRAGALIRRGDNDDAFADYDKAIGINPELSAAYYNNGIILVLKGDYDRAITYLDQ
HHHHHHHCCHHEECCCCCCCHHHHHHHCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHH
AIFLDPDNAEFYYNRGVAWSYKGNDERAIADYDAAIKLNPGDARAYHNRGLNWARKGDKE
EEEECCCCCCEEEECCEEEEECCCCCCEEECCCCEEEECCCCHHHHHHCCCCHHHCCCCH
RAIADYSQAISLDPKNASSYNNRGDAWDSKGDDDRAMADYNQVIILDTKNAHAYYRRGLI
HHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCHHHHHCCEE
WSRKGDDSRAIADYSQVISLDPTDPSIRYNKGLAWLRKGDGDRAIADFDEAIRLDPKMAA
EECCCCCCHHHHHHHHEEEECCCCCCEEECCCEEEEECCCCCCCHHHHHHHHHCCHHHHH
AYYDRGTEWLRKGDRDRAITDYSEVITLEPTNAMALNDRGFVLNELGEYERALADLNRAI
HHHHCCHHHHHCCCCCCEECCHHHEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
GLDPKQAKIYSNRAIARAAKGDFAPALADYNQAIALDPNFPNAYAGRGFVNFYSGMLAKA
CCCCHHHHHHCCHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHHHHHHCHHCCC
EPDFAKAAALAPDNAYLAIWLDIIDRRSGGTSHLREAIAKLDMSKWPAPVIKMLLGQKTS
CCCHHHHHCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
AETLADAGTGDSAQTSGQVCEANFYTAELDRLQARNEEAVRLYRLAARTCPKGYIEYRGA
HHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
VAGLRSLGMLP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]