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The map label for this gene is atzC [H]

Identifier: 13471934

GI number: 13471934

Start: 1687893

End: 1689140

Strand: Reverse

Name: atzC [H]

Synonym: mll2061

Alternate gene names: 13471934

Gene position: 1689140-1687893 (Counterclockwise)

Preceding gene: 13471935

Following gene: 13471933

Centisome position: 24.01

GC content: 67.87

Gene sequence:

>1248_bases
ATGAGCGAGCAAGCGATTTTGAGCGAGCAGACGATTTTCCGCAATGCGAAACTGGCCGATGGGTCGCTGGCGGATCTCTT
CGTCACCGGCGGCCGCTTCCGCGCCATCGCGCCGGCCGGCAAGGCGCCGCCGGCCGATTTCGCCGCCATCGACCCCGCTG
ACATCGATCTCAGCGGCCAGCTTGTCGTGCCGGCCTTCGTCGAGGGGCACATCCATCTCGACACCTCGTTTTATGGCGAT
GCCTGGCGCCCGCACATTCCCTGCACCAACGGCTTCGACGTGCGCGAGCGTGTCGCCTTCCAGGCGCGAAACCTTGCCGC
CGCCGCGCCGATGGCGGAGCGCGCGAAGAACCAGCTCGAGCTCTGCGTCGGCAATGGCAGCCTGGCCATGCGCAGCCATG
TCATGGTCGACGCCTCGGTCGGACTCCGCCATGTCGAAACCATCCTGGCCGTCCGCGAAAAATACCGCGACCTCATCGAC
ATCCAGCTCGTCGCCTTCCCGCAAAGCGGCATCCTGTCCTCGCCGGGCACGGCGGAACTGCTGGACGAGGCGCTGAAGCT
CGGCTGCGATCTCATCGGCGGGCTCGACCCCGCCAGCTTCGACCGTGACGTGAACGGCCATCTCGATGTGGTCTTCGCCC
TGGCGCAGAAGCATGGCGCCGGCGTCGACATCCACCTGCATGATGGCGGCGCGCTCGGCCTGTTCCAGGTCGAGGAGATC
GCCGCGCGGACAAAGGCGCTCGGCATGGCGGGCCATGTCGCCGTCAGCCACGCCTATGGTCTTGGCGACATCCCGGCCGA
CGCCCTGGCGAAGGCCGGCGCGATGCTGGCGGCGGCTGGCGTGGCGATCATGACCAACGCGCCCGGCAACCATGCCTTCC
CGCCGGTGGCGGCCCTGCGGCAGGCCGGCGTCACCGTGTTCAGCGGTTCCGACAACATCCGCGATTCCTGGTGGCCCTAT
GGCGATGGCGACATGCTGAACCGGGCCAATATGATCGGCTACCGCTCCGGCTTCTACGAGGACCGCGAGCTCGAGGCGGC
CTTCGATGTGGTGACCCATGCCGGCGCCAGGGCGCTGGGGCTGGCGGACTATGGCATTGCCGTCGGCGCCAGCGCCGACT
TCGTCGCCATGCCGGCGCAGCACGTGCCCGAAGCGGTGGTGGCCGTGCCGAAGGACCGCACGGTCTATCGGCGGGGCAAA
GCGGTGGCGAGGGTTGGCAAGATGCTGGGCGTCAGCACCTCTTATTAG

Upstream 100 bases:

>100_bases
CGGAACCAGGGGCAATGCGCGAAACAGTTTTTCGTCGCTGCCGCATTGACCCGCAGCGGGCGGGCGGCGAGGACTGGCGC
TTTCGGCAGGGATGGCGCCC

Downstream 100 bases:

>100_bases
GCTTTCCTGCCAAGCTGCGGCCTATTTGTTGCTGCCGTGCAACGGGACGCACTTAAAAACACGCTCGCCTGAAACTTTCC
GTTCTTTCAGTTACAGCCGG

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSEQAILSEQTIFRNAKLADGSLADLFVTGGRFRAIAPAGKAPPADFAAIDPADIDLSGQLVVPAFVEGHIHLDTSFYGD
AWRPHIPCTNGFDVRERVAFQARNLAAAAPMAERAKNQLELCVGNGSLAMRSHVMVDASVGLRHVETILAVREKYRDLID
IQLVAFPQSGILSSPGTAELLDEALKLGCDLIGGLDPASFDRDVNGHLDVVFALAQKHGAGVDIHLHDGGALGLFQVEEI
AARTKALGMAGHVAVSHAYGLGDIPADALAKAGAMLAAAGVAIMTNAPGNHAFPPVAALRQAGVTVFSGSDNIRDSWWPY
GDGDMLNRANMIGYRSGFYEDRELEAAFDVVTHAGARALGLADYGIAVGASADFVAMPAQHVPEAVVAVPKDRTVYRRGK
AVARVGKMLGVSTSY

Sequences:

>Translated_415_residues
MSEQAILSEQTIFRNAKLADGSLADLFVTGGRFRAIAPAGKAPPADFAAIDPADIDLSGQLVVPAFVEGHIHLDTSFYGD
AWRPHIPCTNGFDVRERVAFQARNLAAAAPMAERAKNQLELCVGNGSLAMRSHVMVDASVGLRHVETILAVREKYRDLID
IQLVAFPQSGILSSPGTAELLDEALKLGCDLIGGLDPASFDRDVNGHLDVVFALAQKHGAGVDIHLHDGGALGLFQVEEI
AARTKALGMAGHVAVSHAYGLGDIPADALAKAGAMLAAAGVAIMTNAPGNHAFPPVAALRQAGVTVFSGSDNIRDSWWPY
GDGDMLNRANMIGYRSGFYEDRELEAAFDVVTHAGARALGLADYGIAVGASADFVAMPAQHVPEAVVAVPKDRTVYRRGK
AVARVGKMLGVSTSY
>Mature_414_residues
SEQAILSEQTIFRNAKLADGSLADLFVTGGRFRAIAPAGKAPPADFAAIDPADIDLSGQLVVPAFVEGHIHLDTSFYGDA
WRPHIPCTNGFDVRERVAFQARNLAAAAPMAERAKNQLELCVGNGSLAMRSHVMVDASVGLRHVETILAVREKYRDLIDI
QLVAFPQSGILSSPGTAELLDEALKLGCDLIGGLDPASFDRDVNGHLDVVFALAQKHGAGVDIHLHDGGALGLFQVEEIA
ARTKALGMAGHVAVSHAYGLGDIPADALAKAGAMLAAAGVAIMTNAPGNHAFPPVAALRQAGVTVFSGSDNIRDSWWPYG
DGDMLNRANMIGYRSGFYEDRELEAAFDVVTHAGARALGLADYGIAVGASADFVAMPAQHVPEAVVAVPKDRTVYRRGKA
VARVGKMLGVSTSY

Specific function: Transforms N-isopropylammelide to cyanuric acid and isopropylamine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family [H]

Homologues:

Organism=Escherichia coli, GI1786531, Length=420, Percent_Identity=30.7142857142857, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786517, Length=356, Percent_Identity=29.2134831460674, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.99.4 [H]

Molecular weight: Translated: 43683; Mature: 43552

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQAILSEQTIFRNAKLADGSLADLFVTGGRFRAIAPAGKAPPADFAAIDPADIDLSGQ
CCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
LVVPAFVEGHIHLDTSFYGDAWRPHIPCTNGFDVRERVAFQARNLAAAAPMAERAKNQLE
EEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCEE
LCVGNGSLAMRSHVMVDASVGLRHVETILAVREKYRDLIDIQLVAFPQSGILSSPGTAEL
EEECCCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHH
LDEALKLGCDLIGGLDPASFDRDVNGHLDVVFALAQKHGAGVDIHLHDGGALGLFQVEEI
HHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHEEHHHCCCCEEEEEECCCEEEHHHHHHH
AARTKALGMAGHVAVSHAYGLGDIPADALAKAGAMLAAAGVAIMTNAPGNHAFPPVAALR
HHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHCHHHHHCCEEEEECCCCCCCCCHHHHHH
QAGVTVFSGSDNIRDSWWPYGDGDMLNRANMIGYRSGFYEDRELEAAFDVVTHAGARALG
HCCEEEECCCCCCCCCCCCCCCCCHHCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LADYGIAVGASADFVAMPAQHVPEAVVAVPKDRTVYRRGKAVARVGKMLGVSTSY
EECCCEEECCCCCEEECCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEQAILSEQTIFRNAKLADGSLADLFVTGGRFRAIAPAGKAPPADFAAIDPADIDLSGQ
CCHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCC
LVVPAFVEGHIHLDTSFYGDAWRPHIPCTNGFDVRERVAFQARNLAAAAPMAERAKNQLE
EEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCEE
LCVGNGSLAMRSHVMVDASVGLRHVETILAVREKYRDLIDIQLVAFPQSGILSSPGTAEL
EEECCCCEEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHH
LDEALKLGCDLIGGLDPASFDRDVNGHLDVVFALAQKHGAGVDIHLHDGGALGLFQVEEI
HHHHHHHCHHHHCCCCCCCCCCCCCCCHHHHHEEHHHCCCCEEEEEECCCEEEHHHHHHH
AARTKALGMAGHVAVSHAYGLGDIPADALAKAGAMLAAAGVAIMTNAPGNHAFPPVAALR
HHHHHHHCCHHHEEEHHCCCCCCCCHHHHHHHCHHHHHCCEEEEECCCCCCCCCHHHHHH
QAGVTVFSGSDNIRDSWWPYGDGDMLNRANMIGYRSGFYEDRELEAAFDVVTHAGARALG
HCCEEEECCCCCCCCCCCCCCCCCHHCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LADYGIAVGASADFVAMPAQHVPEAVVAVPKDRTVYRRGKAVARVGKMLGVSTSY
EECCCEEECCCCCEEECCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9422605 [H]