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The map label for this gene is minC

Identifier: 13471845

GI number: 13471845

Start: 1606234

End: 1606980

Strand: Reverse

Name: minC

Synonym: mll1951

Alternate gene names: 13471845

Gene position: 1606980-1606234 (Counterclockwise)

Preceding gene: 13471846

Following gene: 13471844

Centisome position: 22.84

GC content: 68.81

Gene sequence:

>747_bases
ATGGTGGAGTGGCTGCAGGGGCTGGATCACTGGATCGGCAACTCGCCAGGCTATTTTGCCGGGCGGCCGGTGCTGCTCGA
TCTGAACGTTTTGAAGCCCGCGCCGAGCGAGATCGCGGCGCTGGTGGCGGAGCTGGGGACGCGCGGCATCCGCATCTATG
CCATCGAACTGGAAGGGGCTTCGCTCGGGCCTGACCTGCCGCCTCTGCTGGTCGGCGCCAAGGAGGCGACGACGGAGGGG
CTGCTGCCCGGCCGCAAGGGCGGGCAAGAGGGTTCCGGCAAGCCGGACGGCAAGGCTGCCGAGGGCAGGGCGCCGGACCA
TGGCACGGAGGGCCGCGCGGATGCCGGCGCCGCCGGCAAGGGCAAGGCTGGCGCAAGCAAGACTGACGAAAGCGGGCCGC
AGGTTTCGCACTACGATTCGGGCACGCTGATGATCAAGACGCCGATCCGTTCCGGCCAGGCGATCATGCATGCGCATGGC
GATGTCATCGTGCTGGGCTCGGTCGCGTCCGGTTCGGAGATCGTCGCCGCCGGCTCGATCCATGTCTACGGCACGCTGCG
CGGGCGGGCTTCTGCGGGCGCGCTGGGCAACACCGCCGCGCGCATCTTCTGCCGCCGCAACGAGGCCGAGCTTCTGTCGG
TCGACGGCTGGTACATCACCGCCGAGGAGATGGAAGGGGTGTCGCGCGGAAAACCGGTGCAGGCCTTCCTCGATGGAGAC
GGCCTGCGCGTCGAAACACTGAGCTGA

Upstream 100 bases:

>100_bases
GGATTCGCCAGCCGTGACCTTTGCCGCTCCCCTCGAGGCCAAATCCATTCGCTTTCGTGCCCGTTCTTTCGTCGCTTTCA
CATTGACCCCGGAAGCGCCC

Downstream 100 bases:

>100_bases
GAACGGTCGTCAGGGCGGCCGACTGAGAAAACAGGCCGGTGCGGCCAACTGAAGGCCGGCAAGCCGGCCCGGGATAAAAC
GAACAACAATGGAGGCTTTT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGASLGPDLPPLLVGAKEATTEG
LLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGKGKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHG
DVIVLGSVASGSEIVAAGSIHVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGD
GLRVETLS

Sequences:

>Translated_248_residues
MVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGASLGPDLPPLLVGAKEATTEG
LLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGKGKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHG
DVIVLGSVASGSEIVAAGSIHVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGD
GLRVETLS
>Mature_248_residues
MVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGASLGPDLPPLLVGAKEATTEG
LLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGKGKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHG
DVIVLGSVASGSEIVAAGSIHVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGD
GLRVETLS

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=243, Percent_Identity=28.3950617283951, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_RHILO (Q98JG8)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103412.1
- ProteinModelPortal:   Q98JG8
- GeneID:   1226073
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1951
- NMPDR:   fig|266835.1.peg.1516
- HOGENOM:   HBG399077
- ProtClustDB:   PRK05177
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 25513; Mature: 25513

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGA
CCHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCC
SLGPDLPPLLVGAKEATTEGLLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGK
CCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHGDVIVLGSVASGSEIVAAGSI
CCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCEEEEEECCCCCEEEEECCE
HVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGD
EEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCEEEEHHHHCCCCCCCCEEEEECCC
GLRVETLS
CEEEEECC
>Mature Secondary Structure
MVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGA
CCHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCC
SLGPDLPPLLVGAKEATTEGLLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGK
CCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHGDVIVLGSVASGSEIVAAGSI
CCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCEEEEECCCEEEEEECCCCCEEEEECCE
HVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGD
EEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCEEEEHHHHCCCCCCCCEEEEECCC
GLRVETLS
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968