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The map label for this gene is yrpG [H]

Identifier: 13471846

GI number: 13471846

Start: 1607901

End: 1608947

Strand: Reverse

Name: yrpG [H]

Synonym: mll1952

Alternate gene names: 13471846

Gene position: 1608947-1607901 (Counterclockwise)

Preceding gene: 13471848

Following gene: 13471845

Centisome position: 22.87

GC content: 60.27

Gene sequence:

>1047_bases
ATGCGATACAAACTTTTCGGCGAGCACACTGGACTGCGGGTTTCCGAACTGGTTCTCGGAACGGGCAACTTCGGTACGGG
CTGGGGGTACGGCGCCGAACGCGACGAATCCTTGGGCATTTTCGATGCGTATGCGGAAGCCGGCGGCAACTTCATCGACA
CTGCGGGTGTCTACCAAGGTGGCCAAGCCGAAGAGTTCCTGGGCGAGGCCTTGGCCGGGCGACGTGAAGATTTCGTTGTG
GCTACGAAGTACTCGATGCCGGCAGGTTCCAGAGGCGGTATCTTGGCGACTGGCAACAGCCGCAAGGCGATGGTTATCTC
GGTCGAGGACAGCCTTAAGCGTCTGAAGACCGACTACATCGATCTCCTGTGGATCCACATGTCGGATGGTGTGACACCGG
CCGAGGAGATCGTGCGCGGATTTGATGATCTCGTACGCTCGGGAAAGATCCTGTACGCGGGCCTCTCTGATTTCCCGGCG
TGGCGTGTCGCGCGGGCGGCTACTATCGCCGAGCTTCGCGGTGTCGCTCCGATCGCCGGCCTGCAGTACGAACACAGCCT
GGTCGAACGTACGACCGAGCAGGAGTTGCTGCCTGCAGGCAAGGCGCTAGGTCTTGGTCTGGTTGCATGGTCACCACTCG
GCGGCGGCATGCTCACCGGTAAGTATCGCAGAGGCGAGAAGGGCCGTCGCGAAGGATTCGGCGGAAACGTTTTCCAGCCG
GAAAATTCGCTACAGCGAACAGAAATTCTCGACACTTTGATCGCTGTCGCGCAGGAGGTCGGCGTGACGTCTGGGGAGGT
CGCGATTGCCTGGGTTGCAGCCAAGGGCTCGCTCCCGATTATCGGACCGCGGACCGTTGCGCAGCTTGAAAACAATCTTG
CAGCGGCAAACGTTCGCCTCTCGGTGGAACAGATTGCTCGCCTCGACGACGCCAGCGCAATCCCGACAGTGTTCCCCTAC
ACCGTCTTGAACGGCCCGGGCACCAGGCAGGGCTATACTGGCGGCAAGTCTGACCATTTCGATGCTCCTGCACTTTCCGT
TGCTTAA

Upstream 100 bases:

>100_bases
TCATCGCGCTTTTTTAGTTGCGGTCGCCATCAAAGTCAAATATCTAGTGCGCAGATGGTTTGATTGCGATCGCCATCAAT
AAACGAATGGAGAGACACCT

Downstream 100 bases:

>100_bases
GGAGTGATTTGACGGAAGTCGACCTCCGTCGCGTACCAGACGCGCGAAGCCGCCCTGGTTTCTCGAGCGCTTCGGAAACA
ACACGCGGTGACCACTACGC

Product: norsolorinic acid reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRYKLFGEHTGLRVSELVLGTGNFGTGWGYGAERDESLGIFDAYAEAGGNFIDTAGVYQGGQAEEFLGEALAGRREDFVV
ATKYSMPAGSRGGILATGNSRKAMVISVEDSLKRLKTDYIDLLWIHMSDGVTPAEEIVRGFDDLVRSGKILYAGLSDFPA
WRVARAATIAELRGVAPIAGLQYEHSLVERTTEQELLPAGKALGLGLVAWSPLGGGMLTGKYRRGEKGRREGFGGNVFQP
ENSLQRTEILDTLIAVAQEVGVTSGEVAIAWVAAKGSLPIIGPRTVAQLENNLAAANVRLSVEQIARLDDASAIPTVFPY
TVLNGPGTRQGYTGGKSDHFDAPALSVA

Sequences:

>Translated_348_residues
MRYKLFGEHTGLRVSELVLGTGNFGTGWGYGAERDESLGIFDAYAEAGGNFIDTAGVYQGGQAEEFLGEALAGRREDFVV
ATKYSMPAGSRGGILATGNSRKAMVISVEDSLKRLKTDYIDLLWIHMSDGVTPAEEIVRGFDDLVRSGKILYAGLSDFPA
WRVARAATIAELRGVAPIAGLQYEHSLVERTTEQELLPAGKALGLGLVAWSPLGGGMLTGKYRRGEKGRREGFGGNVFQP
ENSLQRTEILDTLIAVAQEVGVTSGEVAIAWVAAKGSLPIIGPRTVAQLENNLAAANVRLSVEQIARLDDASAIPTVFPY
TVLNGPGTRQGYTGGKSDHFDAPALSVA
>Mature_348_residues
MRYKLFGEHTGLRVSELVLGTGNFGTGWGYGAERDESLGIFDAYAEAGGNFIDTAGVYQGGQAEEFLGEALAGRREDFVV
ATKYSMPAGSRGGILATGNSRKAMVISVEDSLKRLKTDYIDLLWIHMSDGVTPAEEIVRGFDDLVRSGKILYAGLSDFPA
WRVARAATIAELRGVAPIAGLQYEHSLVERTTEQELLPAGKALGLGLVAWSPLGGGMLTGKYRRGEKGRREGFGGNVFQP
ENSLQRTEILDTLIAVAQEVGVTSGEVAIAWVAAKGSLPIIGPRTVAQLENNLAAANVRLSVEQIARLDDASAIPTVFPY
TVLNGPGTRQGYTGGKSDHFDAPALSVA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=32.0121951219512, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436964, Length=329, Percent_Identity=31.6109422492401, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436962, Length=329, Percent_Identity=31.6109422492401, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436966, Length=320, Percent_Identity=31.5625, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI223718702, Length=281, Percent_Identity=31.3167259786477, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI41152114, Length=284, Percent_Identity=30.9859154929577, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=31.0030395136778, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=30.8868501529052, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41327764, Length=271, Percent_Identity=28.4132841328413, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI223718708, Length=140, Percent_Identity=34.2857142857143, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=37.1875, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=29.940119760479, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788070, Length=309, Percent_Identity=29.7734627831715, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788081, Length=288, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI48994888, Length=317, Percent_Identity=29.3375394321767, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787674, Length=294, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=336, Percent_Identity=33.6309523809524, Blast_Score=192, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=32.6599326599327, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319951, Length=347, Percent_Identity=30.835734870317, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=32.156862745098, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6325169, Length=324, Percent_Identity=29.9382716049383, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=35.4430379746835, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=24.8520710059172, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646155, Length=311, Percent_Identity=28.6173633440514, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37020; Mature: 37020

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYKLFGEHTGLRVSELVLGTGNFGTGWGYGAERDESLGIFDAYAEAGGNFIDTAGVYQG
CCEEEECCCCCCEEEHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCC
GQAEEFLGEALAGRREDFVVATKYSMPAGSRGGILATGNSRKAMVISVEDSLKRLKTDYI
CCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHCCE
DLLWIHMSDGVTPAEEIVRGFDDLVRSGKILYAGLSDFPAWRVARAATIAELRGVAPIAG
EEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
LQYEHSLVERTTEQELLPAGKALGLGLVAWSPLGGGMLTGKYRRGEKGRREGFGGNVFQP
CCHHHHHHHHHHHHHHHCCCHHHCEEEEEECCCCCCEEECCCCCCCCCHHCCCCCCCCCC
ENSLQRTEILDTLIAVAQEVGVTSGEVAIAWVAAKGSLPIIGPRTVAQLENNLAAANVRL
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEE
SVEQIARLDDASAIPTVFPYTVLNGPGTRQGYTGGKSDHFDAPALSVA
EHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRYKLFGEHTGLRVSELVLGTGNFGTGWGYGAERDESLGIFDAYAEAGGNFIDTAGVYQG
CCEEEECCCCCCEEEHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCC
GQAEEFLGEALAGRREDFVVATKYSMPAGSRGGILATGNSRKAMVISVEDSLKRLKTDYI
CCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHCCE
DLLWIHMSDGVTPAEEIVRGFDDLVRSGKILYAGLSDFPAWRVARAATIAELRGVAPIAG
EEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
LQYEHSLVERTTEQELLPAGKALGLGLVAWSPLGGGMLTGKYRRGEKGRREGFGGNVFQP
CCHHHHHHHHHHHHHHHCCCHHHCEEEEEECCCCCCEEECCCCCCCCCHHCCCCCCCCCC
ENSLQRTEILDTLIAVAQEVGVTSGEVAIAWVAAKGSLPIIGPRTVAQLENNLAAANVRL
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEEEE
SVEQIARLDDASAIPTVFPYTVLNGPGTRQGYTGGKSDHFDAPALSVA
EHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]