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The map label for this gene is aglR [H]

Identifier: 13471515

GI number: 13471515

Start: 1254068

End: 1255099

Strand: Direct

Name: aglR [H]

Synonym: mlr1512

Alternate gene names: 13471515

Gene position: 1254068-1255099 (Clockwise)

Preceding gene: 13471509

Following gene: 13471520

Centisome position: 17.82

GC content: 66.86

Gene sequence:

>1032_bases
TTGTCCTTGGCGTCCAGCATCCACGACCTAGCGCGTCACCTGAACATTTCGATCGGCACCGTGTCACGGGCGCTGAACGG
CCGCGCCGACGTCAATGCCGACACGCGCCAACGCGTGCTGGACGCCGCCAAGAAGCTGAACTATTCACCCAATCAGTCCG
GCCGCAGTCTCAGACAAGGCGCGACCCACTCGATCGCCTTCATGCTGCAGCCGCATCCTGGCGACCAGCAATATGGCGAA
CCGTTCTTCATTCCCTTCCTGATCGGGCTGCAGGGCCGCCTTGCCGAAAGCGGGCTCGACCTGACCGTGGTGATGGGCGC
GCCGGGCGACTATCAGCAGGAGCGCCTGCGCCGCGTCGTCGAGACCCGCCGCGCCGACGCCGTGCTACTGGCCTGGACGC
GGCGCGAGGACGAGCGCATCGATTATCTCACACAGGTCGGCTTCCCCTTCGCCACGCTCGGCCGCAGCCGCAGCGGCGGC
AAGGCCTACCCCTCGCTCGACCTCGATTTCGAGAAGGCCGGCAGCGATGCCGTCGACCGGCTGGTGGCGCGCGGCCATCG
CCGCATCGCCGCCATCCGCCCTTCCCTCAATCTCAATTTTGGCTATCTGTTCCTCGACGGTTATCGCAAAGCCCTGAAGC
GGCACGGCATCGACGTCGACCCCGCGCTGATCGCCGATGGCTTCATCAACGAAGCCGGCGGCTACCAGGTGACGCCGCGC
GTGATGCTGGCAAAGGACCGGCCGACGGCTATCATCTTCAACAACGACGCCATGGCGCTCGGCGGCTGCAAGGCGCTCGC
CGAGATGGGCATCCGCCCCGGCCACGACATCGCGGTGTGCGTCATCGTCGACACGCCGCTCTGCCGTTATTTTTCCCCGG
CGCTGACCGCCTTCCGCCCGCCATTGGAGCCGATGGGAAGGCGGCTGGCCGAAATGCTGCTGGCCTCGCTTCCCGCCTTC
GCCGGCCCGGAAGGCCCGCGCATCACCCGCGAAGTCTGGCCGCTGGAACTGATCGCGCGCGACAGCGATTGA

Upstream 100 bases:

>100_bases
CACACCCGATAGCGTAGAATGTCAATCGGCTGTTCGCGAAAATCGTCCCGAAGCCTTGGCCTAGGCGGCAGCCAATGATA
GCCAAGGCAGAGGGGGAGAA

Downstream 100 bases:

>100_bases
TGGCGCAGGCGATCAATCCACCTTCTTCTCGCCCCGCTCGCCAGCCTTGACGATATCGCCCGTCGTGAACAGGATTTCCT
TCAATTCCGCCCGCCAATCC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSLASSIHDLARHLNISIGTVSRALNGRADVNADTRQRVLDAAKKLNYSPNQSGRSLRQGATHSIAFMLQPHPGDQQYGE
PFFIPFLIGLQGRLAESGLDLTVVMGAPGDYQQERLRRVVETRRADAVLLAWTRREDERIDYLTQVGFPFATLGRSRSGG
KAYPSLDLDFEKAGSDAVDRLVARGHRRIAAIRPSLNLNFGYLFLDGYRKALKRHGIDVDPALIADGFINEAGGYQVTPR
VMLAKDRPTAIIFNNDAMALGGCKALAEMGIRPGHDIAVCVIVDTPLCRYFSPALTAFRPPLEPMGRRLAEMLLASLPAF
AGPEGPRITREVWPLELIARDSD

Sequences:

>Translated_343_residues
MSLASSIHDLARHLNISIGTVSRALNGRADVNADTRQRVLDAAKKLNYSPNQSGRSLRQGATHSIAFMLQPHPGDQQYGE
PFFIPFLIGLQGRLAESGLDLTVVMGAPGDYQQERLRRVVETRRADAVLLAWTRREDERIDYLTQVGFPFATLGRSRSGG
KAYPSLDLDFEKAGSDAVDRLVARGHRRIAAIRPSLNLNFGYLFLDGYRKALKRHGIDVDPALIADGFINEAGGYQVTPR
VMLAKDRPTAIIFNNDAMALGGCKALAEMGIRPGHDIAVCVIVDTPLCRYFSPALTAFRPPLEPMGRRLAEMLLASLPAF
AGPEGPRITREVWPLELIARDSD
>Mature_342_residues
SLASSIHDLARHLNISIGTVSRALNGRADVNADTRQRVLDAAKKLNYSPNQSGRSLRQGATHSIAFMLQPHPGDQQYGEP
FFIPFLIGLQGRLAESGLDLTVVMGAPGDYQQERLRRVVETRRADAVLLAWTRREDERIDYLTQVGFPFATLGRSRSGGK
AYPSLDLDFEKAGSDAVDRLVARGHRRIAAIRPSLNLNFGYLFLDGYRKALKRHGIDVDPALIADGFINEAGGYQVTPRV
MLAKDRPTAIIFNNDAMALGGCKALAEMGIRPGHDIAVCVIVDTPLCRYFSPALTAFRPPLEPMGRRLAEMLLASLPAFA
GPEGPRITREVWPLELIARDSD

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=340, Percent_Identity=27.6470588235294, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790194, Length=315, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787948, Length=311, Percent_Identity=26.3665594855305, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=26.9480519480519, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=22.3642172523962, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788474, Length=341, Percent_Identity=26.099706744868, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789202, Length=306, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786540, Length=322, Percent_Identity=27.0186335403727, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=22.7848101265823, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37701; Mature: 37570

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00037 MYB_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLASSIHDLARHLNISIGTVSRALNGRADVNADTRQRVLDAAKKLNYSPNQSGRSLRQG
CCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCC
ATHSIAFMLQPHPGDQQYGEPFFIPFLIGLQGRLAESGLDLTVVMGAPGDYQQERLRRVV
CCEEEEEEECCCCCCCCCCCCEEEHHHHCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHH
ETRRADAVLLAWTRREDERIDYLTQVGFPFATLGRSRSGGKAYPSLDLDFEKAGSDAVDR
HHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHH
LVARGHRRIAAIRPSLNLNFGYLFLDGYRKALKRHGIDVDPALIADGFINEAGGYQVTPR
HHHCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCE
VMLAKDRPTAIIFNNDAMALGGCKALAEMGIRPGHDIAVCVIVDTPLCRYFSPALTAFRP
EEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCC
PLEPMGRRLAEMLLASLPAFAGPEGPRITREVWPLELIARDSD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEEECCCC
>Mature Secondary Structure 
SLASSIHDLARHLNISIGTVSRALNGRADVNADTRQRVLDAAKKLNYSPNQSGRSLRQG
CHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCC
ATHSIAFMLQPHPGDQQYGEPFFIPFLIGLQGRLAESGLDLTVVMGAPGDYQQERLRRVV
CCEEEEEEECCCCCCCCCCCCEEEHHHHCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHH
ETRRADAVLLAWTRREDERIDYLTQVGFPFATLGRSRSGGKAYPSLDLDFEKAGSDAVDR
HHHCCCEEEEEEECCCCHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHH
LVARGHRRIAAIRPSLNLNFGYLFLDGYRKALKRHGIDVDPALIADGFINEAGGYQVTPR
HHHCCCCEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCE
VMLAKDRPTAIIFNNDAMALGGCKALAEMGIRPGHDIAVCVIVDTPLCRYFSPALTAFRP
EEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCC
PLEPMGRRLAEMLLASLPAFAGPEGPRITREVWPLELIARDSD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]