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The map label for this gene is cobT

Identifier: 13471423

GI number: 13471423

Start: 1163932

End: 1164942

Strand: Direct

Name: cobT

Synonym: mlr1389

Alternate gene names: 13471423

Gene position: 1163932-1164942 (Clockwise)

Preceding gene: 13471422

Following gene: 13471427

Centisome position: 16.54

GC content: 68.05

Gene sequence:

>1011_bases
ATGCCCTTCAAATCCCTCGATGAATTGCGCGCCGCTTGCCTCGATCTGCCCGCCGGCAGCGATACCGCCGCAAAGGCCGT
TGCCAGCCGCCAGGACACGCTGACCAAGCCGCAAGGCAGCCTCGGCCGGCTGGAAACCATCGCCGCCTGGCTGGCGCGCT
GGCAGGGCCGCGACATGCCCAAACTTGACCGGGTGAAGGTGTTCGTCTTTGCCGGCAATCACGGCGTCACCGCGCAAGGC
GTGTCGGCCTATCCCTCAGAAGTCACCGTGCAGATGGTGGCGAACTTCGCCGGCGGCGGAGCCGCCATCAACCAGCTCGC
CCGCATCGCCGGCGCCGAGCTCGATGTCATCCCGCTCGATCTCGACCATCCCACCGGCGACTTCACGCAAGTACCGGCAA
TGGATGAGAAAGCCTTCCTTGCCGCTGTCTCGGCTGGCTATGACGCGGTGACGAAGGACCTCGACCTGGTCTGCTTCGGC
GAAATGGGCATCGGCAACACCACACCTGCGGCCGCCATTTCGGCGGCGCTGTTCGGCGGCGGAGCGGAAAAATGGACCGG
ACGCGGCACCGGCGTCGACGATGCCGGCCTGAAGCGCAAGGTGGTCGCCATCGAAGCCGGCCTCAAGCGCCATGCCGCAG
CCCTCGCCGATCCGCTGGGCGTTGCCGCGGCACTCGGCGGGCGCGAACTCGCCGCCATTTTCGGCGCCACGCTAGCCGCG
CGCCATCTCGGCATACCCGTGCTGCTCGACGGCTTCGTCTGCACCGCTGCCGCTGCCCCGCTGGCCAGGCTGCATCCGAC
CGGCCTCTCCCACACAATAGCAGCCCATGTTTCGGCCGAATCGGGCCATCGCCGCCTGCTCGAAGCGCTCGGCCTGCCCC
CCCTGCTCGATCTCGGCATGCGCCTCGGCGAAGGCTCCGGCGCCTGCCTCGCCGTCAACATCGTCCGCTCGGCGCTGGAG
TGCCATGCGAGGATGGCTAGCTTTGCCGAGGCGGGTGTGTCGGAGAAGTAG

Upstream 100 bases:

>100_bases
CGATCGGTGCCCTGCAGCAGGTCAGCGAAATCGCGGTGCTTCTCGTCGCTTCCGTAGCGCTTTCCTCTTGACCTGATTCC
CTTTCGGAGACCTTGCCCCC

Downstream 100 bases:

>100_bases
GGCAATTCCAGGAAAAGCGTGTAACGGTTTTCTGGGAAAGGCGCGTAGCGCTTCCCCTTGGGAATTGCGTCAAAACAAAG
AGATAAAACGGTTCCCCGTT

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPFKSLDELRAACLDLPAGSDTAAKAVASRQDTLTKPQGSLGRLETIAAWLARWQGRDMPKLDRVKVFVFAGNHGVTAQG
VSAYPSEVTVQMVANFAGGGAAINQLARIAGAELDVIPLDLDHPTGDFTQVPAMDEKAFLAAVSAGYDAVTKDLDLVCFG
EMGIGNTTPAAAISAALFGGGAEKWTGRGTGVDDAGLKRKVVAIEAGLKRHAAALADPLGVAAALGGRELAAIFGATLAA
RHLGIPVLLDGFVCTAAAAPLARLHPTGLSHTIAAHVSAESGHRRLLEALGLPPLLDLGMRLGEGSGACLAVNIVRSALE
CHARMASFAEAGVSEK

Sequences:

>Translated_336_residues
MPFKSLDELRAACLDLPAGSDTAAKAVASRQDTLTKPQGSLGRLETIAAWLARWQGRDMPKLDRVKVFVFAGNHGVTAQG
VSAYPSEVTVQMVANFAGGGAAINQLARIAGAELDVIPLDLDHPTGDFTQVPAMDEKAFLAAVSAGYDAVTKDLDLVCFG
EMGIGNTTPAAAISAALFGGGAEKWTGRGTGVDDAGLKRKVVAIEAGLKRHAAALADPLGVAAALGGRELAAIFGATLAA
RHLGIPVLLDGFVCTAAAAPLARLHPTGLSHTIAAHVSAESGHRRLLEALGLPPLLDLGMRLGEGSGACLAVNIVRSALE
CHARMASFAEAGVSEK
>Mature_335_residues
PFKSLDELRAACLDLPAGSDTAAKAVASRQDTLTKPQGSLGRLETIAAWLARWQGRDMPKLDRVKVFVFAGNHGVTAQGV
SAYPSEVTVQMVANFAGGGAAINQLARIAGAELDVIPLDLDHPTGDFTQVPAMDEKAFLAAVSAGYDAVTKDLDLVCFGE
MGIGNTTPAAAISAALFGGGAEKWTGRGTGVDDAGLKRKVVAIEAGLKRHAAALADPLGVAAALGGRELAAIFGATLAAR
HLGIPVLLDGFVCTAAAAPLARLHPTGLSHTIAAHVSAESGHRRLLEALGLPPLLDLGMRLGEGSGACLAVNIVRSALEC
HARMASFAEAGVSEK

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=337, Percent_Identity=34.4213649851632, Blast_Score=163, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_RHILO (Q98KN9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102989.1
- ProteinModelPortal:   Q98KN9
- SMR:   Q98KN9
- GeneID:   1225652
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr1389
- NMPDR:   fig|266835.1.peg.1094
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   CLSK863262
- BRENDA:   2.4.2.21
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 34409; Mature: 34278

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: ACT_SITE 304-304

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFKSLDELRAACLDLPAGSDTAAKAVASRQDTLTKPQGSLGRLETIAAWLARWQGRDMP
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
KLDRVKVFVFAGNHGVTAQGVSAYPSEVTVQMVANFAGGGAAINQLARIAGAELDVIPLD
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEE
LDHPTGDFTQVPAMDEKAFLAAVSAGYDAVTKDLDLVCFGEMGIGNTTPAAAISAALFGG
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCC
GAEKWTGRGTGVDDAGLKRKVVAIEAGLKRHAAALADPLGVAAALGGRELAAIFGATLAA
CCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RHLGIPVLLDGFVCTAAAAPLARLHPTGLSHTIAAHVSAESGHRRLLEALGLPPLLDLGM
HHCCCHHHHHHHHHHHHHCCHHHCCCCCCCHHEEEEECCCHHHHHHHHHHCCCHHHHHHH
RLGEGSGACLAVNIVRSALECHARMASFAEAGVSEK
HCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PFKSLDELRAACLDLPAGSDTAAKAVASRQDTLTKPQGSLGRLETIAAWLARWQGRDMP
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCC
KLDRVKVFVFAGNHGVTAQGVSAYPSEVTVQMVANFAGGGAAINQLARIAGAELDVIPLD
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEE
LDHPTGDFTQVPAMDEKAFLAAVSAGYDAVTKDLDLVCFGEMGIGNTTPAAAISAALFGG
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCC
GAEKWTGRGTGVDDAGLKRKVVAIEAGLKRHAAALADPLGVAAALGGRELAAIFGATLAA
CCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RHLGIPVLLDGFVCTAAAAPLARLHPTGLSHTIAAHVSAESGHRRLLEALGLPPLLDLGM
HHCCCHHHHHHHHHHHHHCCHHHCCCCCCCHHEEEEECCCHHHHHHHHHHCCCHHHHHHH
RLGEGSGACLAVNIVRSALECHARMASFAEAGVSEK
HCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968