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The map label for this gene is cobG [H]

Identifier: 13471412

GI number: 13471412

Start: 1154230

End: 1155726

Strand: Direct

Name: cobG [H]

Synonym: mlr1378

Alternate gene names: 13471412

Gene position: 1154230-1155726 (Clockwise)

Preceding gene: 13471411

Following gene: 13471413

Centisome position: 16.4

GC content: 67.07

Gene sequence:

>1497_bases
ATGAACGCCTTCTCACGTCGCGGCGCCTGTCCGGCCCTGTCGGCGCCGATGCAGACCGGCGACGGGCTGTTGGTGCGGCT
CAACGCGGTCTATGTGGGATTGTCGCCGAAGCTGTCGATCGGTCTGGCCGAATCCGCCCTGCGGCATGGCAACGGCATCA
TGGAAGTGACAGCGCGTGGAAGCCTGCAGATACGCGGACTGACCAGGGAAAGCGCTGCACTGCTCGCGGCGGAAGTCGAT
GCGCTGGGCATTGCGGTGCGCACCGGAGTGCCGGTGGAGACAGGGCCGCTGGCGGGCATCGACCCGCGGGAGATCGCCGA
TCCGCGACCGCTGGCTGAGCGGATCAGGGCGGCGGTTGAAGAGGCCGGGCTGACGCCAAGACTGGGGCCGAAGGTGTCTG
TCGTGGTGGATGGCGGCGGGCAGCTAACACTGGATGCGGTGACGGCCGATGTGCGGTTGAAAGCGTTGCGGAGTGGTGCC
GGGGTTCGGTGGCAGGTGTCTGTTGCGGGTGATGGGCAGAGTGCAAGATTGCTGGTCGCGGCGGAAGACCACGCGGCCCG
CGATGTCACGGTTGCGGTGCTCAGAATGGTGGCCGAGAAAGGCCGCGAGGCTCACGCAAGAGATTTGTCGGAGCGGCAAT
TAGTATCTCTCGCAGGCTGGCATTCTGTGGCGCCCCCCTCTGTCCTGCCGGACATCTCCCCCACGAGGGGGGAGATCAGC
AGCTTCGCCGCCGGCTCCCTTTCTGAAACCATGCCGCATGTTTCGGCGCCTGGAGTTGGCGAAACCGGCGGCGCAGGCAT
AATCTCCCCCCTCGTGGGGGAGATGTCCGGCAGGACAGAGGGGGGCGCCTCGCGCAAACCTATCGGCCTTTTCCCCATAG
CCGGCGACACTTTCACTCTCGGTATAGGCCTCCCCTACGGCAGCATGCCGGCGGATAAAATCATCGACCTTGCGCAAAGC
GCCGTCACCCTCGGCACCAGCGAAATCCGCCTCGCCCCGGGCCGCGCCCTGCTCTTCCTCGGCCAACCATCCGCCGCCAA
CCAATCCCTCCAAACCATCGCCGCCGCCCTCGGCTTCGTCACCTCCCCTTCCGACCCGCGCACGCGCATCGCCGCCTGCC
CCGGCACGCCGGCCTGCGCCTCCGGCCGCATCGCCACCCGCACCATCGCCGAGACGATCGCCGCCGAAAACGCCGACACC
CTCGACTTCACGCTGCACATTTCCGGCTGCGCCAAGGGCTGCGCGCATCCCGGTCCGGCGGCGCTCACAATCGTCGGCGG
CGAAAATGGAGCCGGACTTGTCGTGAACGCGACGGCAAAGGCCCTTCCTGCGGGCTACAGGCCGGGCTATGACGCCGCGC
GCGGTATCGGTCGCGTCGCGGCGGTGATCCGCAGCGCACGATTTCAAGGCGAGACCGCCGCTGCTTGCCTGACAAGGCTC
GGGCCGGCGGCAATCGCCGAGGCTTACCGACAGGCCCAAACTAAAAAACGGAAATGA

Upstream 100 bases:

>100_bases
TGTCGGCGCGCCGGCGCGGACTCTGGCATCCCTTGCGCAATTCCATCGACGACGATCTCGCCGCGCTGATTGCCGAGGCC
GAGGCGCTGGGAGTGGCGGC

Downstream 100 bases:

>100_bases
GCATGGCCGCCTACGACTACATTCACGACGGCACGGCGATCTACGAGCGCTCCTTCGCCATCATCCGCGCCGAGGCGGAC
CTTTCTCGCTTCTCCGAAGC

Product: cobalamin synthesis protein cobG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MNAFSRRGACPALSAPMQTGDGLLVRLNAVYVGLSPKLSIGLAESALRHGNGIMEVTARGSLQIRGLTRESAALLAAEVD
ALGIAVRTGVPVETGPLAGIDPREIADPRPLAERIRAAVEEAGLTPRLGPKVSVVVDGGGQLTLDAVTADVRLKALRSGA
GVRWQVSVAGDGQSARLLVAAEDHAARDVTVAVLRMVAEKGREAHARDLSERQLVSLAGWHSVAPPSVLPDISPTRGEIS
SFAAGSLSETMPHVSAPGVGETGGAGIISPLVGEMSGRTEGGASRKPIGLFPIAGDTFTLGIGLPYGSMPADKIIDLAQS
AVTLGTSEIRLAPGRALLFLGQPSAANQSLQTIAAALGFVTSPSDPRTRIAACPGTPACASGRIATRTIAETIAAENADT
LDFTLHISGCAKGCAHPGPAALTIVGGENGAGLVVNATAKALPAGYRPGYDAARGIGRVAAVIRSARFQGETAAACLTRL
GPAAIAEAYRQAQTKKRK

Sequences:

>Translated_498_residues
MNAFSRRGACPALSAPMQTGDGLLVRLNAVYVGLSPKLSIGLAESALRHGNGIMEVTARGSLQIRGLTRESAALLAAEVD
ALGIAVRTGVPVETGPLAGIDPREIADPRPLAERIRAAVEEAGLTPRLGPKVSVVVDGGGQLTLDAVTADVRLKALRSGA
GVRWQVSVAGDGQSARLLVAAEDHAARDVTVAVLRMVAEKGREAHARDLSERQLVSLAGWHSVAPPSVLPDISPTRGEIS
SFAAGSLSETMPHVSAPGVGETGGAGIISPLVGEMSGRTEGGASRKPIGLFPIAGDTFTLGIGLPYGSMPADKIIDLAQS
AVTLGTSEIRLAPGRALLFLGQPSAANQSLQTIAAALGFVTSPSDPRTRIAACPGTPACASGRIATRTIAETIAAENADT
LDFTLHISGCAKGCAHPGPAALTIVGGENGAGLVVNATAKALPAGYRPGYDAARGIGRVAAVIRSARFQGETAAACLTRL
GPAAIAEAYRQAQTKKRK
>Mature_498_residues
MNAFSRRGACPALSAPMQTGDGLLVRLNAVYVGLSPKLSIGLAESALRHGNGIMEVTARGSLQIRGLTRESAALLAAEVD
ALGIAVRTGVPVETGPLAGIDPREIADPRPLAERIRAAVEEAGLTPRLGPKVSVVVDGGGQLTLDAVTADVRLKALRSGA
GVRWQVSVAGDGQSARLLVAAEDHAARDVTVAVLRMVAEKGREAHARDLSERQLVSLAGWHSVAPPSVLPDISPTRGEIS
SFAAGSLSETMPHVSAPGVGETGGAGIISPLVGEMSGRTEGGASRKPIGLFPIAGDTFTLGIGLPYGSMPADKIIDLAQS
AVTLGTSEIRLAPGRALLFLGQPSAANQSLQTIAAALGFVTSPSDPRTRIAACPGTPACASGRIATRTIAETIAAENADT
LDFTLHISGCAKGCAHPGPAALTIVGGENGAGLVVNATAKALPAGYRPGYDAARGIGRVAAVIRSARFQGETAAACLTRL
GPAAIAEAYRQAQTKKRK

Specific function: Catalyzes the elimination of C-20 in precorrin-3A to form precorrin-3B [H]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012798
- InterPro:   IPR005117
- InterPro:   IPR006066 [H]

Pfam domain/function: PF03460 NIR_SIR_ferr [H]

EC number: =1.14.13.83 [H]

Molecular weight: Translated: 50657; Mature: 50657

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFSRRGACPALSAPMQTGDGLLVRLNAVYVGLSPKLSIGLAESALRHGNGIMEVTARG
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEECHHHHHHHHCCCCEEEEEECC
SLQIRGLTRESAALLAAEVDALGIAVRTGVPVETGPLAGIDPREIADPRPLAERIRAAVE
CEEEEECCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHH
EAGLTPRLGPKVSVVVDGGGQLTLDAVTADVRLKALRSGAGVRWQVSVAGDGQSARLLVA
HCCCCCCCCCEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEE
AEDHAARDVTVAVLRMVAEKGREAHARDLSERQLVSLAGWHSVAPPSVLPDISPTRGEIS
ECCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
SFAAGSLSETMPHVSAPGVGETGGAGIISPLVGEMSGRTEGGASRKPIGLFPIAGDTFTL
HHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEE
GIGLPYGSMPADKIIDLAQSAVTLGTSEIRLAPGRALLFLGQPSAANQSLQTIAAALGFV
EEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHC
TSPSDPRTRIAACPGTPACASGRIATRTIAETIAAENADTLDFTLHISGCAKGCAHPGPA
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCHHCCCCCCCCE
ALTIVGGENGAGLVVNATAKALPAGYRPGYDAARGIGRVAAVIRSARFQGETAAACLTRL
EEEEEECCCCCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GPAAIAEAYRQAQTKKRK
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNAFSRRGACPALSAPMQTGDGLLVRLNAVYVGLSPKLSIGLAESALRHGNGIMEVTARG
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEECHHHHHHHHCCCCEEEEEECC
SLQIRGLTRESAALLAAEVDALGIAVRTGVPVETGPLAGIDPREIADPRPLAERIRAAVE
CEEEEECCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHH
EAGLTPRLGPKVSVVVDGGGQLTLDAVTADVRLKALRSGAGVRWQVSVAGDGQSARLLVA
HCCCCCCCCCEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEE
AEDHAARDVTVAVLRMVAEKGREAHARDLSERQLVSLAGWHSVAPPSVLPDISPTRGEIS
ECCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
SFAAGSLSETMPHVSAPGVGETGGAGIISPLVGEMSGRTEGGASRKPIGLFPIAGDTFTL
HHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEE
GIGLPYGSMPADKIIDLAQSAVTLGTSEIRLAPGRALLFLGQPSAANQSLQTIAAALGFV
EEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHC
TSPSDPRTRIAACPGTPACASGRIATRTIAETIAAENADTLDFTLHISGCAKGCAHPGPA
CCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCHHCCCCCCCCE
ALTIVGGENGAGLVVNATAKALPAGYRPGYDAARGIGRVAAVIRSARFQGETAAACLTRL
EEEEEECCCCCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GPAAIAEAYRQAQTKKRK
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]