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The map label for this gene is ompR [H]

Identifier: 13471380

GI number: 13471380

Start: 1117595

End: 1118362

Strand: Direct

Name: ompR [H]

Synonym: mlr1334

Alternate gene names: 13471380

Gene position: 1117595-1118362 (Clockwise)

Preceding gene: 13471379

Following gene: 13471381

Centisome position: 15.88

GC content: 61.85

Gene sequence:

>768_bases
ATGCAGGCTGCGGCAAGCTCCGGCCGGATCGATCTGAACGCCGAGTTCAAATCGGCGAGGCAAGGCCCGCATATCCTCAT
TGTCGAAGACGATATCGAGATCGCGCGGATGCTGGGCGAGACGCTCACTGAAAACGGCATGATCGTCGAAATCGCCGGCA
ACGGCGCCCGCATGAACGCCGCGCTTCGCAACCAGAAATTCGATCTCATCGTGCTCGATATCATGCTGCCTGGCGAGAAC
GGCCTCAGCATCTGCCGCCGGCTCCGTGCGCACACGAACGTTCCGATCCTGATGCTGACCGCGCTTGGCGAGGAAATCGA
CCGCATCTTCGGACTGGAAATCGGCGCCGACGACTACGTGACCAAACCGTTCAGCGCGCGCGAACTGACGGCAAGGATAA
GGGCGCTGCTGCGCCGCACGGCCTACGCTCCCGACGAACGGGACCGGACAAAGGTGCTTCGCTTCAACGGCTGGCGCCTC
GATCCCGTTCGCCGGCAATTGCATGATCCCAGCAATGCGCGGGTTGCGACCACGACGCATGAATTCGATCTTCTGCTGGC
GTTTTGCCGCAATGCGGGCCGGGTTCTGTCGCGCGAGGAGCTTCTCAGCGTCACCCATGCCGGGCTTGCCGGGCCGATCG
AGCGAAGCGTCGATGTCCATGTCAGCCGGATCCGCCAGAAGATCGAAAAGGATGCGCGCGATCCGGTTCTTCTCAAAACT
GTCCGGCTGGGTGGCTATATCTTCACCGCCACGGTGGAGGAAGCGTGA

Upstream 100 bases:

>100_bases
TTATGGGGGACGCTGCCGACAGCCCCATTGTCGTCAACAAGGTCCAGCCCTCGGGAATGCTTCTCGTCGGATATCGGTTT
TGATGCCCACACACAGTGCA

Downstream 100 bases:

>100_bases
GGGATTTGGTCAGCCGCTTCCTGCCGCAGTCGGTGCGTGGGCAGTTCGCTGCGATCATTTTCATGGCGGTGATCGCGATC
ATGTCCGCCGGATCGGTCGT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MQAAASSGRIDLNAEFKSARQGPHILIVEDDIEIARMLGETLTENGMIVEIAGNGARMNAALRNQKFDLIVLDIMLPGEN
GLSICRRLRAHTNVPILMLTALGEEIDRIFGLEIGADDYVTKPFSARELTARIRALLRRTAYAPDERDRTKVLRFNGWRL
DPVRRQLHDPSNARVATTTHEFDLLLAFCRNAGRVLSREELLSVTHAGLAGPIERSVDVHVSRIRQKIEKDARDPVLLKT
VRLGGYIFTATVEEA

Sequences:

>Translated_255_residues
MQAAASSGRIDLNAEFKSARQGPHILIVEDDIEIARMLGETLTENGMIVEIAGNGARMNAALRNQKFDLIVLDIMLPGEN
GLSICRRLRAHTNVPILMLTALGEEIDRIFGLEIGADDYVTKPFSARELTARIRALLRRTAYAPDERDRTKVLRFNGWRL
DPVRRQLHDPSNARVATTTHEFDLLLAFCRNAGRVLSREELLSVTHAGLAGPIERSVDVHVSRIRQKIEKDARDPVLLKT
VRLGGYIFTATVEEA
>Mature_255_residues
MQAAASSGRIDLNAEFKSARQGPHILIVEDDIEIARMLGETLTENGMIVEIAGNGARMNAALRNQKFDLIVLDIMLPGEN
GLSICRRLRAHTNVPILMLTALGEEIDRIFGLEIGADDYVTKPFSARELTARIRALLRRTAYAPDERDRTKVLRFNGWRL
DPVRRQLHDPSNARVATTTHEFDLLLAFCRNAGRVLSREELLSVTHAGLAGPIERSVDVHVSRIRQKIEKDARDPVLLKT
VRLGGYIFTATVEEA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=43.4782608695652, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=40.9282700421941, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=40.0862068965517, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=41.3333333333333, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=34.7826086956522, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=39.1304347826087, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=37.219730941704, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=34.9344978165939, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.1233480176211, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=33.4782608695652, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=31.5555555555556, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=35.1464435146443, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28472; Mature: 28472

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAASSGRIDLNAEFKSARQGPHILIVEDDIEIARMLGETLTENGMIVEIAGNGARMNA
CCCCCCCCCEEECCHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEHH
ALRNQKFDLIVLDIMLPGENGLSICRRLRAHTNVPILMLTALGEEIDRIFGLEIGADDYV
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCEECCCCCC
TKPFSARELTARIRALLRRTAYAPDERDRTKVLRFNGWRLDPVRRQLHDPSNARVATTTH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECHHHHHHCCCCCCEEEEEHH
EFDLLLAFCRNAGRVLSREELLSVTHAGLAGPIERSVDVHVSRIRQKIEKDARDPVLLKT
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VRLGGYIFTATVEEA
EEECCEEEEEEECCC
>Mature Secondary Structure
MQAAASSGRIDLNAEFKSARQGPHILIVEDDIEIARMLGETLTENGMIVEIAGNGARMNA
CCCCCCCCCEEECCHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCEEHH
ALRNQKFDLIVLDIMLPGENGLSICRRLRAHTNVPILMLTALGEEIDRIFGLEIGADDYV
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCEECCCCCC
TKPFSARELTARIRALLRRTAYAPDERDRTKVLRFNGWRLDPVRRQLHDPSNARVATTTH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEECHHHHHHCCCCCCEEEEEHH
EFDLLLAFCRNAGRVLSREELLSVTHAGLAGPIERSVDVHVSRIRQKIEKDARDPVLLKT
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VRLGGYIFTATVEEA
EEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]