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The map label for this gene is alkR [H]

Identifier: 13471378

GI number: 13471378

Start: 1115591

End: 1116553

Strand: Direct

Name: alkR [H]

Synonym: mlr1331

Alternate gene names: 13471378

Gene position: 1115591-1116553 (Clockwise)

Preceding gene: 13471374

Following gene: 13471379

Centisome position: 15.86

GC content: 62.82

Gene sequence:

>963_bases
ATGGACATCCTCGCTGAAGTGCTCGATCGCGTTCGCCTTGGCGGAACCTTGCTGTTCCACTTCGAGCTCGGCCATCCCTG
GAATCTGTCATTGCCGGCGCGCCCGTACGCCCTGTTCCATTATCTCAGCCGTGGCTCGGCTACCCTCGCGCTCGAAAATG
GACGAGAACTCCACATGACCGAGGGCGACTTTGTTGTCGTCACGCGTGGCGAGCCCCATGTGATCTACTCGGATCGCCGG
ACAGAGCCGTTACCGATTCTCGACATCGATCGACTGGCTGGGCGTCTTGGCCTCATTCGTCACGGAGGCGGCGAGCAACC
GCTCGCGACGATGATCTGTGGCAATTTCACTGTGGCGCGGCCCTCGCGCGGCAGCGTGTTGGAATTGCTGCCGCCCCTGC
TTCTCCTGAAGCCGACGGAAGACGGCGGATGGCTCGAGGCGATTCTGCAACGCATGGTGAGCGAGGCGGCGCACGCGCGT
CCCGGCCAAGGAGTTGCACTCTCACGACTGACAGAAGTGCTCTTCGTCGAGGTGCTGCGAAGCTGGATCAAGTCGCTCGA
CCCCGGGGAAGGCGGTTGGCTGGGGGCGATGGCGGACCCGCACATAGGACCGGCCCTTCAGTTGATCCACGAACGACCGG
ATCGACCCTGGACGCTTGGCGAACTCGGGCAAAGCGTGGGACTTGGTCGTTCGGCGTTTTCGGCCCGCTTCACCAAGCTC
GTCGGCGAGTCCATGTACCGTTATCTGATCTCACGCCGGATGTCGGAGGCCGCATTTCTGCTCGAAACGAGCGACGAGGG
GATAGCACGGATTGCGTTCCGTGTCGGCTATGAGACCGCGGCCGCGTTTTCGAAGCTGTTCCATCGACATCACGGCCTAT
CGCCTGGCCGTTACCGAGCGGCTCGCCGGTCTGACGGTGGCCGGAGGCAAGGGGGCGTTCTGGAAGCAGAAGTCGCCGAT
TGA

Upstream 100 bases:

>100_bases
TGGCTCGACTTGCGATCAACTAATACGTGGCGCATTTGGACGTTAGGCCTCAATCGTCCGAATATTGTGTCTGACCGTCC
GTCGTACTAACATCGGAAGG

Downstream 100 bases:

>100_bases
CCTCCCGCGCTTGTGATGGCGTGCTCCTACAGGAGCCAAGATCAGGCCAAGATTGCGCAACAAAACTTAACATCACTTCA
CGCATGCAGCCATTTTCACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MDILAEVLDRVRLGGTLLFHFELGHPWNLSLPARPYALFHYLSRGSATLALENGRELHMTEGDFVVVTRGEPHVIYSDRR
TEPLPILDIDRLAGRLGLIRHGGGEQPLATMICGNFTVARPSRGSVLELLPPLLLLKPTEDGGWLEAILQRMVSEAAHAR
PGQGVALSRLTEVLFVEVLRSWIKSLDPGEGGWLGAMADPHIGPALQLIHERPDRPWTLGELGQSVGLGRSAFSARFTKL
VGESMYRYLISRRMSEAAFLLETSDEGIARIAFRVGYETAAAFSKLFHRHHGLSPGRYRAARRSDGGRRQGGVLEAEVAD

Sequences:

>Translated_320_residues
MDILAEVLDRVRLGGTLLFHFELGHPWNLSLPARPYALFHYLSRGSATLALENGRELHMTEGDFVVVTRGEPHVIYSDRR
TEPLPILDIDRLAGRLGLIRHGGGEQPLATMICGNFTVARPSRGSVLELLPPLLLLKPTEDGGWLEAILQRMVSEAAHAR
PGQGVALSRLTEVLFVEVLRSWIKSLDPGEGGWLGAMADPHIGPALQLIHERPDRPWTLGELGQSVGLGRSAFSARFTKL
VGESMYRYLISRRMSEAAFLLETSDEGIARIAFRVGYETAAAFSKLFHRHHGLSPGRYRAARRSDGGRRQGGVLEAEVAD
>Mature_320_residues
MDILAEVLDRVRLGGTLLFHFELGHPWNLSLPARPYALFHYLSRGSATLALENGRELHMTEGDFVVVTRGEPHVIYSDRR
TEPLPILDIDRLAGRLGLIRHGGGEQPLATMICGNFTVARPSRGSVLELLPPLLLLKPTEDGGWLEAILQRMVSEAAHAR
PGQGVALSRLTEVLFVEVLRSWIKSLDPGEGGWLGAMADPHIGPALQLIHERPDRPWTLGELGQSVGLGRSAFSARFTKL
VGESMYRYLISRRMSEAAFLLETSDEGIARIAFRVGYETAAAFSKLFHRHHGLSPGRYRAARRSDGGRRQGGVLEAEVAD

Specific function: This protein activates the expression of the alkane 1- monooxygenase AlkM [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786496, Length=304, Percent_Identity=25, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35278; Mature: 35278

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILAEVLDRVRLGGTLLFHFELGHPWNLSLPARPYALFHYLSRGSATLALENGRELHMT
CCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEEEEE
EGDFVVVTRGEPHVIYSDRRTEPLPILDIDRLAGRLGLIRHGGGEQPLATMICGNFTVAR
CCCEEEEECCCCEEEECCCCCCCCCEEEHHHHHHHHHHEECCCCCCCHHHHHCCCEEEEC
PSRGSVLELLPPLLLLKPTEDGGWLEAILQRMVSEAAHARPGQGVALSRLTEVLFVEVLR
CCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SWIKSLDPGEGGWLGAMADPHIGPALQLIHERPDRPWTLGELGQSVGLGRSAFSARFTKL
HHHHHCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
VGESMYRYLISRRMSEAAFLLETSDEGIARIAFRVGYETAAAFSKLFHRHHGLSPGRYRA
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
ARRSDGGRRQGGVLEAEVAD
HHCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MDILAEVLDRVRLGGTLLFHFELGHPWNLSLPARPYALFHYLSRGSATLALENGRELHMT
CCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEEEEE
EGDFVVVTRGEPHVIYSDRRTEPLPILDIDRLAGRLGLIRHGGGEQPLATMICGNFTVAR
CCCEEEEECCCCEEEECCCCCCCCCEEEHHHHHHHHHHEECCCCCCCHHHHHCCCEEEEC
PSRGSVLELLPPLLLLKPTEDGGWLEAILQRMVSEAAHARPGQGVALSRLTEVLFVEVLR
CCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SWIKSLDPGEGGWLGAMADPHIGPALQLIHERPDRPWTLGELGQSVGLGRSAFSARFTKL
HHHHHCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
VGESMYRYLISRRMSEAAFLLETSDEGIARIAFRVGYETAAAFSKLFHRHHGLSPGRYRA
HHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHH
ARRSDGGRRQGGVLEAEVAD
HHCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9546151 [H]