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The map label for this gene is coxM [H]

Identifier: 13471150

GI number: 13471150

Start: 874413

End: 875297

Strand: Direct

Name: coxM [H]

Synonym: mlr1039

Alternate gene names: 13471150

Gene position: 874413-875297 (Clockwise)

Preceding gene: 13471149

Following gene: 13471151

Centisome position: 12.43

GC content: 61.02

Gene sequence:

>885_bases
ATGGCCGTAGCGCTTGTACTCGTTTTGATCGTCGTGGGCTCAGTGTTGTTTCACCTCCTGAGCCCATGGTGGTGGACGCC
GATTGCCTCGAACTGGGCCTATATCGACAACACCATCATCATTACCTTCTGGATCACCGGCGTCGTCTTCGCTGCCGTCG
TGCTTTTCATGGCCTATTGCGTGTTCCGCTTCCGTCATCGGGAGGGAAACCGCGCCGCCTACGAACCGGAGAACAAGCGG
CTCGAATCGTGGCTCACGATCGTCACCGCGGTCGGGGTCACGGCGTTGCTGGTTCCCGGCCTGTTCGTCTGGAGCCGATT
TGTTACCGTTCCACGCGACGCGACTGAGGTCGAGGTCATTGGCCAGCAATGGCAGTGGAGTTTCCGCCTGCCCGGCAAGG
ACGGCAAGCTCGGCACATCGGATACGCGCGACGTTGGTGCCGACAATCCGCTGGGGATCATCCCCAGCGATCCCAATGGT
CGGGACGACGTCGTGGTCGAAGCCGCCGATCTGCATCTGCCGGTCGGCAAACCGGTCAAGATGCTGCTCCGCTCGATCGA
TGTGCTGCATGATTTCTATGTGCCGGAATTCCGCGCCAAGATGGACATGATCCCGGGCTCGGTGACCTATTTCTGGTTCA
CCCCGACCAGGACCGGAACCTTCCAGGTCCTGTGCGCCGAGCTTTGCGGCCAGGGACATCCAATGATGCATGGCGTCGTG
ATGGTCGATACCCAGGAAGATTATGTGGCCTGGCTCGGCCAGCAGCAGACTTTTGCACAATTGTCGGCCCCCAAGCAGAC
GGGGTCGGCGGACGAGACGACGGGACGGACGGCGGCACCGGGTCCCGAAATTGCAGCAAGGCTCGAAACGGTCGGGTCTC
GCTGA

Upstream 100 bases:

>100_bases
GGATAGTCGCCTCTGGAATTGACCCCAAATTAAGCTATGATGCGCTTGGTATTTCTTGGCGGCGGCTTCGCTCCCCCCTC
GAATGCCGGAGGAACGGGAC

Downstream 100 bases:

>100_bases
AAAAGGACACGGAGGTGTTCCTATGGTCGACATCACCCCTGCAGATGGCATTCCGCCGGCCGAAGTCGCGGAAGTCGAAC
TCTACCATCCGCACAGTTGG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAVALVLVLIVVGSVLFHLLSPWWWTPIASNWAYIDNTIIITFWITGVVFAAVVLFMAYCVFRFRHREGNRAAYEPENKR
LESWLTIVTAVGVTALLVPGLFVWSRFVTVPRDATEVEVIGQQWQWSFRLPGKDGKLGTSDTRDVGADNPLGIIPSDPNG
RDDVVVEAADLHLPVGKPVKMLLRSIDVLHDFYVPEFRAKMDMIPGSVTYFWFTPTRTGTFQVLCAELCGQGHPMMHGVV
MVDTQEDYVAWLGQQQTFAQLSAPKQTGSADETTGRTAAPGPEIAARLETVGSR

Sequences:

>Translated_294_residues
MAVALVLVLIVVGSVLFHLLSPWWWTPIASNWAYIDNTIIITFWITGVVFAAVVLFMAYCVFRFRHREGNRAAYEPENKR
LESWLTIVTAVGVTALLVPGLFVWSRFVTVPRDATEVEVIGQQWQWSFRLPGKDGKLGTSDTRDVGADNPLGIIPSDPNG
RDDVVVEAADLHLPVGKPVKMLLRSIDVLHDFYVPEFRAKMDMIPGSVTYFWFTPTRTGTFQVLCAELCGQGHPMMHGVV
MVDTQEDYVAWLGQQQTFAQLSAPKQTGSADETTGRTAAPGPEIAARLETVGSR
>Mature_293_residues
AVALVLVLIVVGSVLFHLLSPWWWTPIASNWAYIDNTIIITFWITGVVFAAVVLFMAYCVFRFRHREGNRAAYEPENKRL
ESWLTIVTAVGVTALLVPGLFVWSRFVTVPRDATEVEVIGQQWQWSFRLPGKDGKLGTSDTRDVGADNPLGIIPSDPNGR
DDVVVEAADLHLPVGKPVKMLLRSIDVLHDFYVPEFRAKMDMIPGSVTYFWFTPTRTGTFQVLCAELCGQGHPMMHGVVM
VDTQEDYVAWLGQQQTFAQLSAPKQTGSADETTGRTAAPGPEIAARLETVGSR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=162, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=217, Percent_Identity=23.5023041474654, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32623; Mature: 32492

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVALVLVLIVVGSVLFHLLSPWWWTPIASNWAYIDNTIIITFWITGVVFAAVVLFMAYC
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHH
VFRFRHREGNRAAYEPENKRLESWLTIVTAVGVTALLVPGLFVWSRFVTVPRDATEVEVI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEE
GQQWQWSFRLPGKDGKLGTSDTRDVGADNPLGIIPSDPNGRDDVVVEAADLHLPVGKPVK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCCHHH
MLLRSIDVLHDFYVPEFRAKMDMIPGSVTYFWFTPTRTGTFQVLCAELCGQGHPMMHGVV
HHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEE
MVDTQEDYVAWLGQQQTFAQLSAPKQTGSADETTGRTAAPGPEIAARLETVGSR
EEECCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AVALVLVLIVVGSVLFHLLSPWWWTPIASNWAYIDNTIIITFWITGVVFAAVVLFMAYC
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHH
VFRFRHREGNRAAYEPENKRLESWLTIVTAVGVTALLVPGLFVWSRFVTVPRDATEVEVI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEE
GQQWQWSFRLPGKDGKLGTSDTRDVGADNPLGIIPSDPNGRDDVVVEAADLHLPVGKPVK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCCHHH
MLLRSIDVLHDFYVPEFRAKMDMIPGSVTYFWFTPTRTGTFQVLCAELCGQGHPMMHGVV
HHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEE
MVDTQEDYVAWLGQQQTFAQLSAPKQTGSADETTGRTAAPGPEIAARLETVGSR
EEECCHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]