The gene/protein map for NC_002678 is currently unavailable.
Definition Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession NC_002678
Length 7,036,071

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The map label for this gene is echA8 [H]

Identifier: 13471124

GI number: 13471124

Start: 835231

End: 836007

Strand: Reverse

Name: echA8 [H]

Synonym: mll1009

Alternate gene names: 13471124

Gene position: 836007-835231 (Counterclockwise)

Preceding gene: 13471125

Following gene: 13471123

Centisome position: 11.88

GC content: 64.35

Gene sequence:

>777_bases
ATGATGGACCGCCTCGTTCAGGCAGTGGAACCGGCGCCCGGCATCCGACTGCTGACGCTCAACCGGCCGGACAAGCTGAA
CGCGTTGTCCAAGGCGTTGCTGGCCGAATTGAGCCACCTGCTTTCTGGCTACGACGCCGACACGGAGGTCGGCTGCGTGG
TGCTGACGGGTGCCGGTCGCGCCTTTGCGGCAGGCGCCGACATCTCTGACATGCTGGAACGCGGGGTCGCCTCCTACGCC
GACCCGGAACGGCTGGCATGCTGGCGCGCCATTGAGGGCTTCACCAAGCCGATTATCGCCGCCGTGAATGGATATGCGCT
GGGCGGCGGGCTGGAGCTTGCGCTTCTGTGCGACATCGTCATTGCCTCGCAAGCAGCTCAATTCGCGACTCCTGAAATCA
AGATCGGCGCGTTTCCCGGCGATGGCGGCACGCAGCGTCTGCCACGTCTCGTCGGCAAATCCTTTGCCATGCAGATGGTC
CTGACCGGTGACATGGTCGATGCGACCCTCGCCGAGCGCAAAGGACTGGTCAGCGAAGTCGTGGAGGCGGACAGGCTCCT
GCCACGGGCGCTGGAGATCGCCGCTGCGATCGCCGCCAAGTCGGTTGCCATCACGCCCTATGCGAAGAAGGCCGTTCTGG
CGGCATTCGAAACCGAACTGCAAAGCGGGCTCGAGATTGAGCACCGGCTGACCGTCGAGGCATTCGGCAAGGAGGACCGG
ATTGAAGGGCTGCGAGCCTTTGCCGAGAAACGGGCGCCGGCCTTCAGGGGCAAATAG

Upstream 100 bases:

>100_bases
ATTGATGAAGCCAGACCCCGCCGAGATCGAGAAGATTCGGGGACTGCTGAATGCTGCCGGATTGAGCGCGGAGACGCTTT
ACAGGAAGGTCGCCTAGTCG

Downstream 100 bases:

>100_bases
GACTGAGGAGCCAGGTCCGCCAGGGGTTCGTTGCGCGGACGGAGAAGGCGCCTTCGGGCGCGAGTGGAGGCAGAACATGT
GGGATTACATAATTGTCGGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMDRLVQAVEPAPGIRLLTLNRPDKLNALSKALLAELSHLLSGYDADTEVGCVVLTGAGRAFAAGADISDMLERGVASYA
DPERLACWRAIEGFTKPIIAAVNGYALGGGLELALLCDIVIASQAAQFATPEIKIGAFPGDGGTQRLPRLVGKSFAMQMV
LTGDMVDATLAERKGLVSEVVEADRLLPRALEIAAAIAAKSVAITPYAKKAVLAAFETELQSGLEIEHRLTVEAFGKEDR
IEGLRAFAEKRAPAFRGK

Sequences:

>Translated_258_residues
MMDRLVQAVEPAPGIRLLTLNRPDKLNALSKALLAELSHLLSGYDADTEVGCVVLTGAGRAFAAGADISDMLERGVASYA
DPERLACWRAIEGFTKPIIAAVNGYALGGGLELALLCDIVIASQAAQFATPEIKIGAFPGDGGTQRLPRLVGKSFAMQMV
LTGDMVDATLAERKGLVSEVVEADRLLPRALEIAAAIAAKSVAITPYAKKAVLAAFETELQSGLEIEHRLTVEAFGKEDR
IEGLRAFAEKRAPAFRGK
>Mature_258_residues
MMDRLVQAVEPAPGIRLLTLNRPDKLNALSKALLAELSHLLSGYDADTEVGCVVLTGAGRAFAAGADISDMLERGVASYA
DPERLACWRAIEGFTKPIIAAVNGYALGGGLELALLCDIVIASQAAQFATPEIKIGAFPGDGGTQRLPRLVGKSFAMQMV
LTGDMVDATLAERKGLVSEVVEADRLLPRALEIAAAIAAKSVAITPYAKKAVLAAFETELQSGLEIEHRLTVEAFGKEDR
IEGLRAFAEKRAPAFRGK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=242, Percent_Identity=47.5206611570248, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI4502327, Length=253, Percent_Identity=35.9683794466403, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI31542718, Length=247, Percent_Identity=31.1740890688259, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI20127408, Length=177, Percent_Identity=37.8531073446328, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI70995211, Length=249, Percent_Identity=29.3172690763052, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI68989263, Length=173, Percent_Identity=36.4161849710983, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI37594469, Length=176, Percent_Identity=32.3863636363636, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI37594471, Length=176, Percent_Identity=32.3863636363636, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=30.0395256916996, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI221136756, Length=247, Percent_Identity=26.7206477732794, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI221136753, Length=247, Percent_Identity=26.7206477732794, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4757968, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=240, Percent_Identity=26.25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=236, Percent_Identity=27.5423728813559, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI25453481, Length=240, Percent_Identity=26.25, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI51538573, Length=240, Percent_Identity=26.25, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI213417737, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157694516, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757966, Length=165, Percent_Identity=31.5151515151515, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI51538581, Length=165, Percent_Identity=31.5151515151515, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI260274832, Length=176, Percent_Identity=32.3863636363636, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI45643119, Length=176, Percent_Identity=32.3863636363636, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI260275230, Length=176, Percent_Identity=32.3863636363636, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI116235487, Length=161, Percent_Identity=32.9192546583851, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI261878539, Length=79, Percent_Identity=44.3037974683544, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=47.1311475409836, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI221142681, Length=252, Percent_Identity=36.5079365079365, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787660, Length=268, Percent_Identity=35.0746268656716, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082183, Length=250, Percent_Identity=29.6, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=31.7460317460317, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790281, Length=182, Percent_Identity=34.0659340659341, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=34.5744680851064, Blast_Score=95, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=46.6403162055336, Blast_Score=226, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=47.1311475409836, Blast_Score=216, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17540714, Length=222, Percent_Identity=34.6846846846847, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=29.3436293436293, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540306, Length=234, Percent_Identity=31.6239316239316, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=35.3591160220994, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=181, Percent_Identity=34.8066298342541, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=181, Percent_Identity=34.8066298342541, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=181, Percent_Identity=34.8066298342541, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=216, Percent_Identity=31.9444444444444, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=267, Percent_Identity=25.8426966292135, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17549921, Length=183, Percent_Identity=32.2404371584699, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25144160, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=173, Percent_Identity=28.3236994219653, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=186, Percent_Identity=30.6451612903226, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=48.9626556016597, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=48.9626556016597, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=34.251968503937, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19922422, Length=258, Percent_Identity=28.2945736434109, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI19920382, Length=236, Percent_Identity=30.9322033898305, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357171, Length=259, Percent_Identity=30.1158301158301, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24650670, Length=208, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24654903, Length=182, Percent_Identity=29.1208791208791, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571729, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571730, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19921000, Length=201, Percent_Identity=34.3283582089552, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583077, Length=179, Percent_Identity=36.3128491620112, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583079, Length=179, Percent_Identity=36.3128491620112, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27317; Mature: 27317

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MMDRLVQAVEPAPGIRLLTLNRPDKLNALSKALLAELSHLLSGYDADTEVGCVVLTGAGR
CHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
AFAAGADISDMLERGVASYADPERLACWRAIEGFTKPIIAAVNGYALGGGLELALLCDIV
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHH
IASQAAQFATPEIKIGAFPGDGGTQRLPRLVGKSFAMQMVLTGDMVDATLAERKGLVSEV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VEADRLLPRALEIAAAIAAKSVAITPYAKKAVLAAFETELQSGLEIEHRLTVEAFGKEDR
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCHHEEEHHHCCCHHH
IEGLRAFAEKRAPAFRGK
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMDRLVQAVEPAPGIRLLTLNRPDKLNALSKALLAELSHLLSGYDADTEVGCVVLTGAGR
CHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
AFAAGADISDMLERGVASYADPERLACWRAIEGFTKPIIAAVNGYALGGGLELALLCDIV
EEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHH
IASQAAQFATPEIKIGAFPGDGGTQRLPRLVGKSFAMQMVLTGDMVDATLAERKGLVSEV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VEADRLLPRALEIAAAIAAKSVAITPYAKKAVLAAFETELQSGLEIEHRLTVEAFGKEDR
HHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCHHEEEHHHCCCHHH
IEGLRAFAEKRAPAFRGK
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]