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The map label for this gene is rbsC [H]

Identifier: 13471118

GI number: 13471118

Start: 828420

End: 829541

Strand: Reverse

Name: rbsC [H]

Synonym: mll1003

Alternate gene names: 13471118

Gene position: 829541-828420 (Counterclockwise)

Preceding gene: 13471119

Following gene: 13471117

Centisome position: 11.79

GC content: 61.94

Gene sequence:

>1122_bases
ATGACTCTGACCAAAGAACAGAGCACCGCCACAAGTCACTCCGATGAGCGACTGAAGAAAGTCTCGACGATGACCGCGCT
CCTGCGGCGCCCCGAACTCGGCGCTGTTGCAGGCCTGGTGCTCGTGACCATCTTTTTCTTCTTCACCGCAAATCCGGCGA
TGTTCACGCTGGCCGGCATCATGAATTTCATGGCACCTGCCGCCCAACTCGGCATCCTTGCCATCGGCGCGGCTTTACTG
ATGATCGGCGGCGAATTTGATCTCTCGATCGGATCGATGGTGGCTTTTGCCGGGCTGGTCTTCGGCACAGCGCTCGTCGT
TTGGCATGTGCCGCTCAGCGTTGCGATCCTGGTTGCCGTCGCCTTCGCCGTCTTCATCGGCGTCACCAACGCGCAGATCA
CGATGCGCACCGGCCTGCCGTCCTTCATCGTCACGCTGGCGTTTCTGTTCATCCTGCGCGGGCTGACCCTGGTCGGCCTA
AAATGGGCGAGCGGCGGCTCCACCCAGCTTCGCGGCATGAAGGAGGCTGCCGCCGGCAGCCCGCTGGCGCCGTTCTTTTC
GGGCGACGCCTTTTCCAGCCTGTTCTCGTGGCTCGCCGAGAAAGGCATCATCGAGGCATTTCCGAGCGGCGCTCCGAAAG
TGCCGGGCATTCCCGTCGAGATTTTGTGGTTCATAGCGATCGCCCTGCTCGCGACGTGGGTCCTGTTGCGGACGCGTTTT
GGCAACTGGATTTTTGCAGCCGGCGGCGATCCGCGCGCTGCCCGCAAATCCGCCGTGCCGGTTGCGCGGGTAAAGACGAC
GCTCTTCGTGATCACCGCGCTCTGCGCCACGCTGGTTGCCATCCTTACAGTTCTCGATGCTGGCTCGACCGACGCCCGCC
GCGGCTTCCAGAAGGAGTTCGAGGCGATCATCGCTGCCGTCATCGGCGGGTGCCTGCTGACCGGCGGCTATGGCTCGGCA
ATCGGCGCCTTCTTCGGATCGATCGTGTTCGGCATGGTTCTGATCGGACTGACCTACACCTCGATCGACCAGGATTGGTA
CCTCGTCTTTCTGGGCGGCATGCTGCTGATCGCGGTGATTTTCAACAATGTCATCCGCAAGCGCGTAACGGGAGAACGCT
GA

Upstream 100 bases:

>100_bases
GCCGGGCGGTCCTCGCTTCGGCGGGGACCGCTCAATCTTCGTGCAGGACCGGAAGACCGCATCTGTACGGCTTGAGCTTG
ATAGAAATCGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGGCCACATCCCAAACGCCCCTCATTGAGGTCAAGGACATCGTCAAGCATTTCGGCTCGGTCATTGCGCTGAACGGTGTG
TCGATGAGCGTGAATGCGCA

Product: permease protein of sugar ABC transporter

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTLTKEQSTATSHSDERLKKVSTMTALLRRPELGAVAGLVLVTIFFFFTANPAMFTLAGIMNFMAPAAQLGILAIGAALL
MIGGEFDLSIGSMVAFAGLVFGTALVVWHVPLSVAILVAVAFAVFIGVTNAQITMRTGLPSFIVTLAFLFILRGLTLVGL
KWASGGSTQLRGMKEAAAGSPLAPFFSGDAFSSLFSWLAEKGIIEAFPSGAPKVPGIPVEILWFIAIALLATWVLLRTRF
GNWIFAAGGDPRAARKSAVPVARVKTTLFVITALCATLVAILTVLDAGSTDARRGFQKEFEAIIAAVIGGCLLTGGYGSA
IGAFFGSIVFGMVLIGLTYTSIDQDWYLVFLGGMLLIAVIFNNVIRKRVTGER

Sequences:

>Translated_373_residues
MTLTKEQSTATSHSDERLKKVSTMTALLRRPELGAVAGLVLVTIFFFFTANPAMFTLAGIMNFMAPAAQLGILAIGAALL
MIGGEFDLSIGSMVAFAGLVFGTALVVWHVPLSVAILVAVAFAVFIGVTNAQITMRTGLPSFIVTLAFLFILRGLTLVGL
KWASGGSTQLRGMKEAAAGSPLAPFFSGDAFSSLFSWLAEKGIIEAFPSGAPKVPGIPVEILWFIAIALLATWVLLRTRF
GNWIFAAGGDPRAARKSAVPVARVKTTLFVITALCATLVAILTVLDAGSTDARRGFQKEFEAIIAAVIGGCLLTGGYGSA
IGAFFGSIVFGMVLIGLTYTSIDQDWYLVFLGGMLLIAVIFNNVIRKRVTGER
>Mature_372_residues
TLTKEQSTATSHSDERLKKVSTMTALLRRPELGAVAGLVLVTIFFFFTANPAMFTLAGIMNFMAPAAQLGILAIGAALLM
IGGEFDLSIGSMVAFAGLVFGTALVVWHVPLSVAILVAVAFAVFIGVTNAQITMRTGLPSFIVTLAFLFILRGLTLVGLK
WASGGSTQLRGMKEAAAGSPLAPFFSGDAFSSLFSWLAEKGIIEAFPSGAPKVPGIPVEILWFIAIALLATWVLLRTRFG
NWIFAAGGDPRAARKSAVPVARVKTTLFVITALCATLVAILTVLDAGSTDARRGFQKEFEAIIAAVIGGCLLTGGYGSAI
GAFFGSIVFGMVLIGLTYTSIDQDWYLVFLGGMLLIAVIFNNVIRKRVTGER

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=325, Percent_Identity=29.5384615384615, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788896, Length=331, Percent_Identity=28.3987915407855, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082395, Length=337, Percent_Identity=26.1127596439169, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787794, Length=337, Percent_Identity=27.5964391691395, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790524, Length=281, Percent_Identity=27.7580071174377, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789992, Length=134, Percent_Identity=35.8208955223881, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788471, Length=313, Percent_Identity=30.0319488817891, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693152, Length=300, Percent_Identity=28.6666666666667, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 39398; Mature: 39267

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTKEQSTATSHSDERLKKVSTMTALLRRPELGAVAGLVLVTIFFFFTANPAMFTLAGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MNFMAPAAQLGILAIGAALLMIGGEFDLSIGSMVAFAGLVFGTALVVWHVPLSVAILVAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVFIGVTNAQITMRTGLPSFIVTLAFLFILRGLTLVGLKWASGGSTQLRGMKEAAAGS
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCC
PLAPFFSGDAFSSLFSWLAEKGIIEAFPSGAPKVPGIPVEILWFIAIALLATWVLLRTRF
CCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GNWIFAAGGDPRAARKSAVPVARVKTTLFVITALCATLVAILTVLDAGSTDARRGFQKEF
CCEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EAIIAAVIGGCLLTGGYGSAIGAFFGSIVFGMVLIGLTYTSIDQDWYLVFLGGMLLIAVI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FNNVIRKRVTGER
HHHHHHHHHCCCC
>Mature Secondary Structure 
TLTKEQSTATSHSDERLKKVSTMTALLRRPELGAVAGLVLVTIFFFFTANPAMFTLAGI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MNFMAPAAQLGILAIGAALLMIGGEFDLSIGSMVAFAGLVFGTALVVWHVPLSVAILVAV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVFIGVTNAQITMRTGLPSFIVTLAFLFILRGLTLVGLKWASGGSTQLRGMKEAAAGS
HHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCC
PLAPFFSGDAFSSLFSWLAEKGIIEAFPSGAPKVPGIPVEILWFIAIALLATWVLLRTRF
CCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GNWIFAAGGDPRAARKSAVPVARVKTTLFVITALCATLVAILTVLDAGSTDARRGFQKEF
CCEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EAIIAAVIGGCLLTGGYGSAIGAFFGSIVFGMVLIGLTYTSIDQDWYLVFLGGMLLIAVI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FNNVIRKRVTGER
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]