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The map label for this gene is dnaJ [H]

Identifier: 13471068

GI number: 13471068

Start: 760806

End: 761342

Strand: Direct

Name: dnaJ [H]

Synonym: mlr0945

Alternate gene names: 13471068

Gene position: 760806-761342 (Clockwise)

Preceding gene: 13471067

Following gene: 13471075

Centisome position: 10.81

GC content: 52.33

Gene sequence:

>537_bases
TTGTTCGTTGATTACTACGAACTCCTTGAAATCAGCCCGAACGCCAACTCGGAAACGATAGAACGGGTATTCCGCTATTT
CGCCATGCGCTACCATCCTGACAATCAGGACACCGGCGATGAATCGCGCTTCAGCGAAATCCTGGAAGCCCACAATGTTC
TCAAGGACCCAGTCAAGCGCGCGCAGTATGACATTCAGCACAAGGACCATTTGAGCCTGCGAACAGAGTTGATTGGGGAA
GCCAGCAACAGCACAACTATCGAGCGTGATGTGGCCATTCAGGCGAAATTGCTCTCACTGCTCTACGTCAAACGCCGGCA
AGACGTAAACAATCCCGGTATTGGCGATACAGAAATCGAACGTTTGTCAGGCTGTCCGCGAGAACATCTTGAGTTTCATC
TCTGGTACCTGAAAGCCAAGGGTTGGATTGGAAGGATCGAGAACGGAACCTTCGCGATCACCGTGGAAGGCATCGATCGC
GCCAATTCCGAACATCGCCGTGACGCCACAACAAGACTGCTGGACCATGCAGGCTGA

Upstream 100 bases:

>100_bases
TCGCGCCGATCCAATCCGCAAGTTGAGGACTGTTGTTTCTTGCCTTCAGCGGTCATGCACTCGAGGGTGTGCGCAGTAGC
GATGTTATGGGGGCGCCATC

Downstream 100 bases:

>100_bases
AACGCGCAAGCCAGCGTCTGCGCCGTATCGACTAACCGCCGACCAGCGGCACGGTGACGGTGGTGGCGTAGTTGATCGGA
AAGCTGCTGAGGTAAGGAAA

Product: heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MFVDYYELLEISPNANSETIERVFRYFAMRYHPDNQDTGDESRFSEILEAHNVLKDPVKRAQYDIQHKDHLSLRTELIGE
ASNSTTIERDVAIQAKLLSLLYVKRRQDVNNPGIGDTEIERLSGCPREHLEFHLWYLKAKGWIGRIENGTFAITVEGIDR
ANSEHRRDATTRLLDHAG

Sequences:

>Translated_178_residues
MFVDYYELLEISPNANSETIERVFRYFAMRYHPDNQDTGDESRFSEILEAHNVLKDPVKRAQYDIQHKDHLSLRTELIGE
ASNSTTIERDVAIQAKLLSLLYVKRRQDVNNPGIGDTEIERLSGCPREHLEFHLWYLKAKGWIGRIENGTFAITVEGIDR
ANSEHRRDATTRLLDHAG
>Mature_178_residues
MFVDYYELLEISPNANSETIERVFRYFAMRYHPDNQDTGDESRFSEILEAHNVLKDPVKRAQYDIQHKDHLSLRTELIGE
ASNSTTIERDVAIQAKLLSLLYVKRRQDVNNPGIGDTEIERLSGCPREHLEFHLWYLKAKGWIGRIENGTFAITVEGIDR
ANSEHRRDATTRLLDHAG

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI201862518, Length=65, Percent_Identity=46.1538461538462, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI56549115, Length=65, Percent_Identity=46.1538461538462, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI201862587, Length=65, Percent_Identity=46.1538461538462, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 20612; Mature: 20612

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDYYELLEISPNANSETIERVFRYFAMRYHPDNQDTGDESRFSEILEAHNVLKDPVKR
CCCCHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQYDIQHKDHLSLRTELIGEASNSTTIERDVAIQAKLLSLLYVKRRQDVNNPGIGDTEIE
HHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RLSGCPREHLEFHLWYLKAKGWIGRIENGTFAITVEGIDRANSEHRRDATTRLLDHAG
HHHCCCHHHHEEEEEEEEECCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFVDYYELLEISPNANSETIERVFRYFAMRYHPDNQDTGDESRFSEILEAHNVLKDPVKR
CCCCHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQYDIQHKDHLSLRTELIGEASNSTTIERDVAIQAKLLSLLYVKRRQDVNNPGIGDTEIE
HHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RLSGCPREHLEFHLWYLKAKGWIGRIENGTFAITVEGIDRANSEHRRDATTRLLDHAG
HHHCCCHHHHEEEEEEEEECCCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10570966 [H]