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The map label for this gene is map [H]

Identifier: 13471075

GI number: 13471075

Start: 777018

End: 777845

Strand: Direct

Name: map [H]

Synonym: mlr0954

Alternate gene names: 13471075

Gene position: 777018-777845 (Clockwise)

Preceding gene: 13471068

Following gene: 13471076

Centisome position: 11.04

GC content: 65.7

Gene sequence:

>828_bases
ATGGTCACCTATCTCGACGCCGCCACGGCCCCTCTCAGAAACACCGGCCAGATCCGCCTCTATGGCGAGGATGGTTTTGC
CGGCATGCGCAAGGCATGCGACCTCACCGCGCGTTGCCTGGACGCGCTGGTGCCGATGGTCGGGCCCGGCGTCACCACGG
ACGCCATCGACCGTTTCGTCTTCGAGTTCGGCATGGATCACGGCGCGCTGCCGGCGACGCTCAACTATCGCGGCTACACG
AAATCGTCCTGCACCTCGATCAACCATGTCGTCTGCCACGGCATTCCCGACAACAAACCGCTGAAGGACGGCGACATCGT
CAACATCGACGTCACCTACATTCTCGACGGCTGGCATGGCGATTCCTCGCGCATGTATCCGGTCGGCACCATCAAGCGCG
CGGCCGAACGCCTGCTCGAGGTCACCCATGAATGCCTGATGCGCGGCATCGCCGCCGTCAGGCCGGGTGCCCGCACCGGC
GCCATCGGCGCCGCCATCCAGACTTTTGCCGAGGCGGAGCGCTGCTCGGTGGTGCGCGACTTCTGCGGCCACGGCGTCGG
CCAGCTCTTCCACGACGCCCCCAACATCCTGCACTATGGCAGCGCCAATGAAGGCGTCGAGATGCGGCCCGGCATGATCT
TCACCATCGAGCCGATGATCAATCTCGGCCGCCCGCATGTGAAGGTGCTGTCGGATGGCTGGACGGCGGTGACGCGGGAC
CGTTCGCTGTCGGCGCAGTACGAGCACACGATCGGCGTGACCGACACGGGCTGCGAGATCTTCACGCTCTCGCCCAACAA
CCTCGACCGGCCTGGCCTGCCGGCCTGA

Upstream 100 bases:

>100_bases
ATCAGCCAGTTCTTCCTTGAACCTTTTGCCCTCAAGTGCCAAATCTTGCGGGATATTCACGCCAGCACTCCTGCAGCGCC
CACCCTTCTATACGGACAAA

Downstream 100 bases:

>100_bases
TATTTTAATACGTCGGGCGACCGCTTTGCCCGACTGGCTAGCTGGATGCGGGGGCTGATGGGGAAGGCCAGCGACGACGA
CGAGCGGAGTTTCTTCGCCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MVTYLDAATAPLRNTGQIRLYGEDGFAGMRKACDLTARCLDALVPMVGPGVTTDAIDRFVFEFGMDHGALPATLNYRGYT
KSSCTSINHVVCHGIPDNKPLKDGDIVNIDVTYILDGWHGDSSRMYPVGTIKRAAERLLEVTHECLMRGIAAVRPGARTG
AIGAAIQTFAEAERCSVVRDFCGHGVGQLFHDAPNILHYGSANEGVEMRPGMIFTIEPMINLGRPHVKVLSDGWTAVTRD
RSLSAQYEHTIGVTDTGCEIFTLSPNNLDRPGLPA

Sequences:

>Translated_275_residues
MVTYLDAATAPLRNTGQIRLYGEDGFAGMRKACDLTARCLDALVPMVGPGVTTDAIDRFVFEFGMDHGALPATLNYRGYT
KSSCTSINHVVCHGIPDNKPLKDGDIVNIDVTYILDGWHGDSSRMYPVGTIKRAAERLLEVTHECLMRGIAAVRPGARTG
AIGAAIQTFAEAERCSVVRDFCGHGVGQLFHDAPNILHYGSANEGVEMRPGMIFTIEPMINLGRPHVKVLSDGWTAVTRD
RSLSAQYEHTIGVTDTGCEIFTLSPNNLDRPGLPA
>Mature_275_residues
MVTYLDAATAPLRNTGQIRLYGEDGFAGMRKACDLTARCLDALVPMVGPGVTTDAIDRFVFEFGMDHGALPATLNYRGYT
KSSCTSINHVVCHGIPDNKPLKDGDIVNIDVTYILDGWHGDSSRMYPVGTIKRAAERLLEVTHECLMRGIAAVRPGARTG
AIGAAIQTFAEAERCSVVRDFCGHGVGQLFHDAPNILHYGSANEGVEMRPGMIFTIEPMINLGRPHVKVLSDGWTAVTRD
RSLSAQYEHTIGVTDTGCEIFTLSPNNLDRPGLPA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=46.8992248062016, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=41.7670682730924, Blast_Score=205, Evalue=4e-53,
Organism=Escherichia coli, GI1786364, Length=252, Percent_Identity=51.984126984127, Blast_Score=260, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=45.8167330677291, Blast_Score=226, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6323273, Length=260, Percent_Identity=44.6153846153846, Blast_Score=226, Evalue=3e-60,
Organism=Drosophila melanogaster, GI21355531, Length=260, Percent_Identity=44.6153846153846, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24583427, Length=234, Percent_Identity=45.2991452991453, Blast_Score=207, Evalue=5e-54,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29776; Mature: 29776

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTYLDAATAPLRNTGQIRLYGEDGFAGMRKACDLTARCLDALVPMVGPGVTTDAIDRFV
CEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FEFGMDHGALPATLNYRGYTKSSCTSINHVVCHGIPDNKPLKDGDIVNIDVTYILDGWHG
HHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECEEC
DSSRMYPVGTIKRAAERLLEVTHECLMRGIAAVRPGARTGAIGAAIQTFAEAERCSVVRD
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FCGHGVGQLFHDAPNILHYGSANEGVEMRPGMIFTIEPMINLGRPHVKVLSDGWTAVTRD
HHCCCHHHHHHCCCCEEEECCCCCCCEECCCEEEEECHHHCCCCCCEEEEECCCEEEECC
RSLSAQYEHTIGVTDTGCEIFTLSPNNLDRPGLPA
CCCCCCHHEECCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MVTYLDAATAPLRNTGQIRLYGEDGFAGMRKACDLTARCLDALVPMVGPGVTTDAIDRFV
CEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FEFGMDHGALPATLNYRGYTKSSCTSINHVVCHGIPDNKPLKDGDIVNIDVTYILDGWHG
HHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECEEC
DSSRMYPVGTIKRAAERLLEVTHECLMRGIAAVRPGARTGAIGAAIQTFAEAERCSVVRD
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FCGHGVGQLFHDAPNILHYGSANEGVEMRPGMIFTIEPMINLGRPHVKVLSDGWTAVTRD
HHCCCHHHHHHCCCCEEEECCCCCCCEECCCEEEEECHHHCCCCCCEEEEECCCEEEECC
RSLSAQYEHTIGVTDTGCEIFTLSPNNLDRPGLPA
CCCCCCHHEECCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]