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The map label for this gene is aatC [H]

Identifier: 13471061

GI number: 13471061

Start: 753284

End: 754495

Strand: Reverse

Name: aatC [H]

Synonym: mll0935

Alternate gene names: 13471061

Gene position: 754495-753284 (Counterclockwise)

Preceding gene: 13471062

Following gene: 13471060

Centisome position: 10.72

GC content: 64.44

Gene sequence:

>1212_bases
ATGGAAGAGTTTCACAAGGTCCGCCGGCTTCCGCCTTACGTGTTCGAGCAGGTCAACCGGCTCAAGGCCAGCGCCCGTTC
GCGCGGCGCCGACATTATCGACCTCGGCATGGGCAATCCGGACCTGCCGACGCCCAAGGCCATCGTCGACAAATTGTGCG
AAGTGGTGCGCGATCCGCGCACGCATCGCTATTCCTCCTCGCGCGGCATTCCCGGCCTGCGCCGCGCTCAGGCCGCCTAT
TATCAGCGCCGCTTCGGCGTGAAGCTCAACCCCGACACGCAAGTGGTGGCCACGCTCGGCTCAAAGGAAGGCTTCGCCAA
CATGGCGCAGGCGATCACCGCGCCTGGCGACGTCATCCTGTGCCCGAACCCGACCTATCCGATCCATGCCTTCGGCTTCA
TCATGTCGGGCGGCGTCATCCGCTCGCTGCAGGTCGAGCCGGACGATGGTTTCATTCCAGCGCTGGAACGCGGCGTTCGC
CACTCGATCCCCAAGCCGCTGGCGTTGATCCTCAACTATCCGTCGAACCCGACGGCACTGGTCGCTTCGCTCGACTTCTA
CAAGGACGTGGTGGCGTTCGCGAAGAAGAACGACATCATCATCCTGTCCGACCTTGCCTATTCGGAGATCTATTTCGACG
GCAACCCGCCACCTTCGGTGTTGCAGGTGCCCGGCGCCATCGATGTCTGCGTCGAGTTCACCTCGATGTCGAAGACCTTC
TCCATGCCCGGCTGGCGCATGGGTTTTGCAGTCGGCAATGAGCGGCTGATCTCGGCGCTGACGCGGGTGAAGTCCTATCT
CGACTACGGCGCCTTCACGCCGATCCAGGTGGCGGCGGCCCATGCGCTCAACGGCGACGAAATCGCAGAGGTGCGCGAGG
TCTACCACAAGCGCCGCGACGTGATGGTCGATTCCTTCGGGCGCGCCGGCTGGAACATTCCGGCCCCGGCCGCCTCGATG
TTCGCCTGGGCGCCGATCCCCGAACCGTTCAAGCATCTGGGCTCGCTCGAATTCTCCAAGCTGCTCATCGAGCACGCCGA
CGTGGCGGTGGCGCCCGGTGTCGGCTTCGGCGAGCATGGCGACGATTTCGTGCGCCTGGCGCTGGTGGAGAACGAGCACC
GGATCCGCCAGGCGGCGCGCAACATCAAGCGCTTCCTGTCGACCAGCGCCAAGCAGCCCAACAATGTGGTGCCGCTGTCC
GCCCACCGGTAA

Upstream 100 bases:

>100_bases
GCTGAAGCAGATCGAAGGCAAATGCGATCCCGCCCTCGACCCTACCTGCAAATGAGTATATAGCGCGCGCCCAATACCCC
TTTTGCTGTCTGGAACTGCC

Downstream 100 bases:

>100_bases
GCAAAATTCGATCTGATTTTGAGGGACGTCGCCTTCCATGGCTGAAGCTCTGCGTGTTGGAATTGCCGGACTTGGCACGG
TGGGTGCAGCGGTGGCGCGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YQRRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFIMSGGVIRSLQVEPDDGFIPALERGVR
HSIPKPLALILNYPSNPTALVASLDFYKDVVAFAKKNDIIILSDLAYSEIYFDGNPPPSVLQVPGAIDVCVEFTSMSKTF
SMPGWRMGFAVGNERLISALTRVKSYLDYGAFTPIQVAAAHALNGDEIAEVREVYHKRRDVMVDSFGRAGWNIPAPAASM
FAWAPIPEPFKHLGSLEFSKLLIEHADVAVAPGVGFGEHGDDFVRLALVENEHRIRQAARNIKRFLSTSAKQPNNVVPLS
AHR

Sequences:

>Translated_403_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YQRRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFIMSGGVIRSLQVEPDDGFIPALERGVR
HSIPKPLALILNYPSNPTALVASLDFYKDVVAFAKKNDIIILSDLAYSEIYFDGNPPPSVLQVPGAIDVCVEFTSMSKTF
SMPGWRMGFAVGNERLISALTRVKSYLDYGAFTPIQVAAAHALNGDEIAEVREVYHKRRDVMVDSFGRAGWNIPAPAASM
FAWAPIPEPFKHLGSLEFSKLLIEHADVAVAPGVGFGEHGDDFVRLALVENEHRIRQAARNIKRFLSTSAKQPNNVVPLS
AHR
>Mature_403_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YQRRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFIMSGGVIRSLQVEPDDGFIPALERGVR
HSIPKPLALILNYPSNPTALVASLDFYKDVVAFAKKNDIIILSDLAYSEIYFDGNPPPSVLQVPGAIDVCVEFTSMSKTF
SMPGWRMGFAVGNERLISALTRVKSYLDYGAFTPIQVAAAHALNGDEIAEVREVYHKRRDVMVDSFGRAGWNIPAPAASM
FAWAPIPEPFKHLGSLEFSKLLIEHADVAVAPGVGFGEHGDDFVRLALVENEHRIRQAARNIKRFLSTSAKQPNNVVPLS
AHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=22.4489795918367, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=22.4489795918367, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=23.3333333333333, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=23.3333333333333, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI169881281, Length=242, Percent_Identity=21.900826446281, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=51.2755102040816, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=24.8704663212435, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788627, Length=281, Percent_Identity=28.1138790035587, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787710, Length=334, Percent_Identity=24.251497005988, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=400, Percent_Identity=23, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=263, Percent_Identity=26.615969581749, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=263, Percent_Identity=26.615969581749, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=21.3917525773196, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=25.706940874036, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=25.706940874036, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=25.706940874036, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=25.706940874036, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44371; Mature: 44371

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPR
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSRGIPGLRRAQAAYYQRRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFIMSGGVIRSLQVEPDDGFIPALERGVRHSIPKPLALILNYPSNPTAL
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEE
VASLDFYKDVVAFAKKNDIIILSDLAYSEIYFDGNPPPSVLQVPGAIDVCVEFTSMSKTF
EEHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHC
SMPGWRMGFAVGNERLISALTRVKSYLDYGAFTPIQVAAAHALNGDEIAEVREVYHKRRD
CCCCCEEEHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
VMVDSFGRAGWNIPAPAASMFAWAPIPEPFKHLGSLEFSKLLIEHADVAVAPGVGFGEHG
HHHHCCCCCCCCCCCCHHHHEEECCCCHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCC
DDFVRLALVENEHRIRQAARNIKRFLSTSAKQPNNVVPLSAHR
CCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC
>Mature Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPR
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSRGIPGLRRAQAAYYQRRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFIMSGGVIRSLQVEPDDGFIPALERGVRHSIPKPLALILNYPSNPTAL
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEE
VASLDFYKDVVAFAKKNDIIILSDLAYSEIYFDGNPPPSVLQVPGAIDVCVEFTSMSKTF
EEHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHC
SMPGWRMGFAVGNERLISALTRVKSYLDYGAFTPIQVAAAHALNGDEIAEVREVYHKRRD
CCCCCEEEHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
VMVDSFGRAGWNIPAPAASMFAWAPIPEPFKHLGSLEFSKLLIEHADVAVAPGVGFGEHG
HHHHCCCCCCCCCCCCHHHHEEECCCCHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCC
DDFVRLALVENEHRIRQAARNIKRFLSTSAKQPNNVVPLSAHR
CCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]