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The map label for this gene is glpX [H]

Identifier: 13471057

GI number: 13471057

Start: 750044

End: 751027

Strand: Reverse

Name: glpX [H]

Synonym: mll0929

Alternate gene names: 13471057

Gene position: 751027-750044 (Counterclockwise)

Preceding gene: 13471058

Following gene: 13471056

Centisome position: 10.67

GC content: 66.97

Gene sequence:

>984_bases
ATGAATGTGGCCCAGAACATCGTCGCCGGCCTTGACCGGATACTCACCATGGAACTGGTGCGCGTCACCGAAAGGGCCGC
CGTGGCAGCCGCCAGGCTGCGCGGCCGTGGCGACGAGAAGGCTGCCGACCAGGTCGCGGTCGATGCCATGCGCCAGGAGC
TCAACCGCCTTGCCATCAAGGGCACGGTGGTGATCGGCGAGGGCGAGCGCGACGAGGCGCCGATGCTCTATATCGGCGAG
GAGGTCGGCACTGGCAAAGGACCGGCCGTCGACATCGCGCTCGATCCGCTCGAAGGCACGACGATCTGCGCCAAGAACCT
GCCCAACGCGCTTGCCGTCATCGCCATCGCCGAGAAGGGCAGCCTGCTGTTCGCGCCCGACGTCTATATGGACAAGATCG
CCATCGGTCCGGGCTATGCCGAAGGCGTCATCGATATCGACGCCTCGCCAGCCGAAAACATCGCCAGCCTCGCCCGGGCT
AAGGGCGTCGCGGTGTCCGACATCACCACCTGCATCCTCGACCGTCCGCGCCACGCCAAGCTGATCGATGCCGTGCGCGC
CACGGGAGCGGCGATCCGGCTGATCGGTGACGGCGATGTCGCCGGCGTCATCCACACCACCGACCCGGAGGAAACCGGCA
TCGATCTCTATCTCGGCACTGGCGGCGCGCCGGAAGGCGTGCTGGCGGCGGCGGCACTGCGCTGCACCGGCGGCCAGATG
CAGGGCCGGCTGATCCTCGATACGCCGGAAAAGGTCGCGCGCGCCGCCAAAATGGGCATTTCCGATCCGAAGCGGATCTA
TCACGCGGAAGACATGGCGCGCGGCGACGTGCTGTTCGCGGCCACCGGCGTCACCGACGGCAACATGCTGGCCGGCGTCA
AGTTCGGCCGCACCTACATCACCACGCACACGATCGTGCTGCGCTCCTCGTCGCGGACCGTGCGCGAAATCAAGGCCCGG
CACCAGGATCTGGATAAGTTCTAG

Upstream 100 bases:

>100_bases
TTCGATAAAACGCGCGGCAGGTCTTGCCGTTGTCATGCTCGTTTGACAAAACAGGCCCGCCTCCGGCGGGAGGCGGTATG
CCAACGAGGATTTGCCGAAC

Downstream 100 bases:

>100_bases
AGCTCCTTGCGAAGCCGCAGCGCAGTTGCTAGCCCTTGGCTGCATCTGAACCTGGCGGCGCAAGGATTGACGATGAATGC
GTTCGACTGGCACGCGGATC

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNVAQNIVAGLDRILTMELVRVTERAAVAAARLRGRGDEKAADQVAVDAMRQELNRLAIKGTVVIGEGERDEAPMLYIGE
EVGTGKGPAVDIALDPLEGTTICAKNLPNALAVIAIAEKGSLLFAPDVYMDKIAIGPGYAEGVIDIDASPAENIASLARA
KGVAVSDITTCILDRPRHAKLIDAVRATGAAIRLIGDGDVAGVIHTTDPEETGIDLYLGTGGAPEGVLAAAALRCTGGQM
QGRLILDTPEKVARAAKMGISDPKRIYHAEDMARGDVLFAATGVTDGNMLAGVKFGRTYITTHTIVLRSSSRTVREIKAR
HQDLDKF

Sequences:

>Translated_327_residues
MNVAQNIVAGLDRILTMELVRVTERAAVAAARLRGRGDEKAADQVAVDAMRQELNRLAIKGTVVIGEGERDEAPMLYIGE
EVGTGKGPAVDIALDPLEGTTICAKNLPNALAVIAIAEKGSLLFAPDVYMDKIAIGPGYAEGVIDIDASPAENIASLARA
KGVAVSDITTCILDRPRHAKLIDAVRATGAAIRLIGDGDVAGVIHTTDPEETGIDLYLGTGGAPEGVLAAAALRCTGGQM
QGRLILDTPEKVARAAKMGISDPKRIYHAEDMARGDVLFAATGVTDGNMLAGVKFGRTYITTHTIVLRSSSRTVREIKAR
HQDLDKF
>Mature_327_residues
MNVAQNIVAGLDRILTMELVRVTERAAVAAARLRGRGDEKAADQVAVDAMRQELNRLAIKGTVVIGEGERDEAPMLYIGE
EVGTGKGPAVDIALDPLEGTTICAKNLPNALAVIAIAEKGSLLFAPDVYMDKIAIGPGYAEGVIDIDASPAENIASLARA
KGVAVSDITTCILDRPRHAKLIDAVRATGAAIRLIGDGDVAGVIHTTDPEETGIDLYLGTGGAPEGVLAAAALRCTGGQM
QGRLILDTPEKVARAAKMGISDPKRIYHAEDMARGDVLFAATGVTDGNMLAGVKFGRTYITTHTIVLRSSSRTVREIKAR
HQDLDKF

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=323, Percent_Identity=46.749226006192, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789298, Length=321, Percent_Identity=40.809968847352, Blast_Score=214, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34400; Mature: 34400

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAQNIVAGLDRILTMELVRVTERAAVAAARLRGRGDEKAADQVAVDAMRQELNRLAIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEE
GTVVIGEGERDEAPMLYIGEEVGTGKGPAVDIALDPLEGTTICAKNLPNALAVIAIAEKG
EEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEHHCCCCEEEEEEEECCC
SLLFAPDVYMDKIAIGPGYAEGVIDIDASPAENIASLARAKGVAVSDITTCILDRPRHAK
CEEEECCHHHHEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
LIDAVRATGAAIRLIGDGDVAGVIHTTDPEETGIDLYLGTGGAPEGVLAAAALRCTGGQM
HHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
QGRLILDTPEKVARAAKMGISDPKRIYHAEDMARGDVLFAATGVTDGNMLAGVKFGRTYI
CCEEEEECHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCEEE
TTHTIVLRSSSRTVREIKARHQDLDKF
EEEEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVAQNIVAGLDRILTMELVRVTERAAVAAARLRGRGDEKAADQVAVDAMRQELNRLAIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEE
GTVVIGEGERDEAPMLYIGEEVGTGKGPAVDIALDPLEGTTICAKNLPNALAVIAIAEKG
EEEEEECCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEEHHCCCCEEEEEEEECCC
SLLFAPDVYMDKIAIGPGYAEGVIDIDASPAENIASLARAKGVAVSDITTCILDRPRHAK
CEEEECCHHHHEEEECCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
LIDAVRATGAAIRLIGDGDVAGVIHTTDPEETGIDLYLGTGGAPEGVLAAAALRCTGGQM
HHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
QGRLILDTPEKVARAAKMGISDPKRIYHAEDMARGDVLFAATGVTDGNMLAGVKFGRTYI
CCEEEEECHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCEEE
TTHTIVLRSSSRTVREIKARHQDLDKF
EEEEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]