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The map label for this gene is gcvT [H]

Identifier: 13471020

GI number: 13471020

Start: 707925

End: 709025

Strand: Direct

Name: gcvT [H]

Synonym: mlr0883

Alternate gene names: 13471020

Gene position: 707925-709025 (Clockwise)

Preceding gene: 13471018

Following gene: 13471021

Centisome position: 10.06

GC content: 65.4

Gene sequence:

>1101_bases
ATGACGGGCGACGACTCAAAACACCTTCCTCTAGAAGATATCCACACAGCCGCCGGCGCGCGCTTCGGCGCCTTTGCCGG
TTGGTCGATGCCGCTGACCTATCCGGCCGGCGTCATGAAGGAGCATCTGCACACCCGCGAGCATGTCGGTCTCTTCGATA
TCTCGCACATGAAACTGTTCGAGGTCAGCGGGCCGCAGGCGGTTGCACTGCTCAACCGCGCTTGCCCCTTGGATGCCGGC
GCGCTCGAAATCTCGCAGTCGAAACTGTCCTTCTTCCTCAATGAGGCCGGCGGCATTCTCGACGACCTGATCGTCACCCG
GCTCGGCGATACCAGGTTCATGGTGGTCGCCAATGCCGGCAACGCCGTCGCCGACGAAAAGCATCTGCGTGAGCTGGCCA
CGAATTTTGATGTGAAGGTCGAGCCGCTCGACCGCGTCTTCCTCGCTATCCAGGGCCCGGAAGCATGGGCGGCTCTTTCC
CGCGCCGGCATCGAGACCGGCTCGCTGCTGTTCATGCATGGCGTCGAACCGCGGAAAGACTGGTTCATGAGCCGGTCTGG
CTACACTGGCGAGGACGGTTTCGAGATCGGGCTGCCGGAGGCCGACGCGCGCGATCTCGTCGCGAAGCTACTCGAAGATG
AGCGTGTGCTGTGGATCGGCCTTGCCGCGCGCGACAGCCTGCGGCTTGAGGCTGGGCTTTGCCTGCATGGCCAGGACATC
ACGCCGGAGACCGACCCGGCCGCTGCCGCGCTGATGTGGGCAATCCCCAGGGATATCCGCGCTTCCGGGGCGTTCATAGG
CGCCGACGCCTTGCGCGCCGCCGTGGAACGCGGCCCAGCGCAAAAGCGCGTCGGGTTGAAGCCGGAAGGCCGCCAGCCGG
TGCGCGCCGGCGTTGCTCTGTTCGACGCCGACGGCAATCCCGCCGGCCATGTCACATCGGGCGGCTTTGGCCCCTCGGCC
GGCCATCCGGTCGCCATGGGCTATGTCGCCGCATCGCTGGCAAAGCCCGGCACACGGGTGTTCGCCGAGGTACGCGGCAC
GAAGATCCCCGTCGATATCAGTTCCCTGCCCTTCACCCCTCATCGCTACCGCAAAGGATGA

Upstream 100 bases:

>100_bases
CGCTGACAGAGTTCCGGTTGCGCGAGTCTCTCAGGCTTCAGACAGAGGGGCACGGACTGGTCGCCATTCGCGGCCGCTTG
CGTGCGACTCTGGAGACGAC

Downstream 100 bases:

>100_bases
ACCTCATGGCAAAGACCTATTTCACATCAGATCACGAATGGCTCCGCGTTGAGGGCGGCATCGCCACCGTCGGCATCACC
GACTACGCGCAGGAGCAGCT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTGDDSKHLPLEDIHTAAGARFGAFAGWSMPLTYPAGVMKEHLHTREHVGLFDISHMKLFEVSGPQAVALLNRACPLDAG
ALEISQSKLSFFLNEAGGILDDLIVTRLGDTRFMVVANAGNAVADEKHLRELATNFDVKVEPLDRVFLAIQGPEAWAALS
RAGIETGSLLFMHGVEPRKDWFMSRSGYTGEDGFEIGLPEADARDLVAKLLEDERVLWIGLAARDSLRLEAGLCLHGQDI
TPETDPAAAALMWAIPRDIRASGAFIGADALRAAVERGPAQKRVGLKPEGRQPVRAGVALFDADGNPAGHVTSGGFGPSA
GHPVAMGYVAASLAKPGTRVFAEVRGTKIPVDISSLPFTPHRYRKG

Sequences:

>Translated_366_residues
MTGDDSKHLPLEDIHTAAGARFGAFAGWSMPLTYPAGVMKEHLHTREHVGLFDISHMKLFEVSGPQAVALLNRACPLDAG
ALEISQSKLSFFLNEAGGILDDLIVTRLGDTRFMVVANAGNAVADEKHLRELATNFDVKVEPLDRVFLAIQGPEAWAALS
RAGIETGSLLFMHGVEPRKDWFMSRSGYTGEDGFEIGLPEADARDLVAKLLEDERVLWIGLAARDSLRLEAGLCLHGQDI
TPETDPAAAALMWAIPRDIRASGAFIGADALRAAVERGPAQKRVGLKPEGRQPVRAGVALFDADGNPAGHVTSGGFGPSA
GHPVAMGYVAASLAKPGTRVFAEVRGTKIPVDISSLPFTPHRYRKG
>Mature_365_residues
TGDDSKHLPLEDIHTAAGARFGAFAGWSMPLTYPAGVMKEHLHTREHVGLFDISHMKLFEVSGPQAVALLNRACPLDAGA
LEISQSKLSFFLNEAGGILDDLIVTRLGDTRFMVVANAGNAVADEKHLRELATNFDVKVEPLDRVFLAIQGPEAWAALSR
AGIETGSLLFMHGVEPRKDWFMSRSGYTGEDGFEIGLPEADARDLVAKLLEDERVLWIGLAARDSLRLEAGLCLHGQDIT
PETDPAAAALMWAIPRDIRASGAFIGADALRAAVERGPAQKRVGLKPEGRQPVRAGVALFDADGNPAGHVTSGGFGPSAG
HPVAMGYVAASLAKPGTRVFAEVRGTKIPVDISSLPFTPHRYRKG

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=371, Percent_Identity=40.9703504043127, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI257796258, Length=352, Percent_Identity=41.1931818181818, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI257796254, Length=367, Percent_Identity=35.4223433242507, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI257796256, Length=317, Percent_Identity=39.7476340694006, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI24797151, Length=351, Percent_Identity=23.3618233618234, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789272, Length=365, Percent_Identity=34.2465753424658, Blast_Score=165, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17560118, Length=378, Percent_Identity=37.037037037037, Blast_Score=208, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320222, Length=383, Percent_Identity=34.9869451697128, Blast_Score=196, Evalue=7e-51,
Organism=Drosophila melanogaster, GI20129441, Length=377, Percent_Identity=37.4005305039788, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 39140; Mature: 39009

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDDSKHLPLEDIHTAAGARFGAFAGWSMPLTYPAGVMKEHLHTREHVGLFDISHMKLF
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCEEEE
EVSGPQAVALLNRACPLDAGALEISQSKLSFFLNEAGGILDDLIVTRLGDTRFMVVANAG
ECCCCHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCC
NAVADEKHLRELATNFDVKVEPLDRVFLAIQGPEAWAALSRAGIETGSLLFMHGVEPRKD
CCCHHHHHHHHHHHCCCEEECCCCEEEEEEECCHHHHHHHHCCCCCCCEEEEECCCCHHH
WFMSRSGYTGEDGFEIGLPEADARDLVAKLLEDERVLWIGLAARDSLRLEAGLCLHGQDI
HHHCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCEEEECCCC
TPETDPAAAALMWAIPRDIRASGAFIGADALRAAVERGPAQKRVGLKPEGRQPVRAGVAL
CCCCCHHHHHHHHHCCHHHHCCCCEECHHHHHHHHHCCCCHHCCCCCCCCCCCHHHCEEE
FDADGNPAGHVTSGGFGPSAGHPVAMGYVAASLAKPGTRVFAEVRGTKIPVDISSLPFTP
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCCCC
HRYRKG
HHCCCC
>Mature Secondary Structure 
TGDDSKHLPLEDIHTAAGARFGAFAGWSMPLTYPAGVMKEHLHTREHVGLFDISHMKLF
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCEEEE
EVSGPQAVALLNRACPLDAGALEISQSKLSFFLNEAGGILDDLIVTRLGDTRFMVVANAG
ECCCCHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCC
NAVADEKHLRELATNFDVKVEPLDRVFLAIQGPEAWAALSRAGIETGSLLFMHGVEPRKD
CCCHHHHHHHHHHHCCCEEECCCCEEEEEEECCHHHHHHHHCCCCCCCEEEEECCCCHHH
WFMSRSGYTGEDGFEIGLPEADARDLVAKLLEDERVLWIGLAARDSLRLEAGLCLHGQDI
HHHCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCEEEECCCC
TPETDPAAAALMWAIPRDIRASGAFIGADALRAAVERGPAQKRVGLKPEGRQPVRAGVAL
CCCCCHHHHHHHHHCCHHHHCCCCEECHHHHHHHHHCCCCHHCCCCCCCCCCCHHHCEEE
FDADGNPAGHVTSGGFGPSAGHPVAMGYVAASLAKPGTRVFAEVRGTKIPVDISSLPFTP
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEECCCCCCCC
HRYRKG
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA