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The map label for this gene is dinB1

Identifier: 13471007

GI number: 13471007

Start: 691609

End: 692925

Strand: Direct

Name: dinB1

Synonym: mlr0866

Alternate gene names: 13471007

Gene position: 691609-692925 (Clockwise)

Preceding gene: 13471005

Following gene: 13471009

Centisome position: 9.83

GC content: 64.69

Gene sequence:

>1317_bases
ATGGCGGCCCCTGTCAACAATCCCGATCACGGTTTTTGCCGTGACTGCCTGACGTTTCAGCGCAGTGAAACGCGCCGCTG
CGAGCGCTGCGGCAGCCCTCGCCTTGCCCGTCATCCCGAGCTCTACCGTCTGCATCTGGCCCATATCGATTGCGACGCCT
TCTACGCGGCGATCGAAAAGCGCGACAACCCGGCGCTCAAGGACAAGCCGCTGATCATCGGCGGCGGCAAGCGCGGGGTC
GTCTCCACCGCTTGCTACATCGCCCGCATCCGGGGCGTGCGCTCCGCCATGCCGATGTTCAAGGCGCTCGAGGCCTGCCC
CGAGGCGGTCGTGATCCCGCCCAACATGGAAAAATATGTGCGTGTCGGCCGCGAGGTGCGCGCCATGATGCAGACGCTGA
CGCCGCTGGTCGAGCCGCTGTCGATCGACGAGGCGTTTCTCGATTTCGCCGGCACCGAACGGTTGCACGGCCAGCCGCCG
GCCGTGGTGCTGGCGCGCTTCGCACTGGCCGTCGAGAAAGAGATCGGCATCACCGTTTCGGCGGGCCTCTCCTATTGCAA
ATTCCTCGCCAAGATCGCATCCGATTTCCGCAAACCACGCGGCTTTTCGGTCATTGGCGAGGCCGAGGCGGTGGGCTTCC
TGGCGACGAAGCCGGTGACGATGATCTGGGGCGTCGGCAAGGCGTTCAACGCCACGCTGGAACGCGACGGCATCCGCACC
ATCGGTCAGCTTCAAACGATGGAACGTGGCGACCTGATGCGCCGCTATGGCGTGATGGGCGACCGGCTCTACCGGCTTTC
GCGTGGTGAGGACGTTCGCCGCGTCGACCCCGACCAGGATGCCAAAAGCGTATCGGCCGAAACCACCTTCGACACCGACA
TCGCATCGTTGGACGAGCTGGTCTCGGTGCTGAGAGGGCTTTCGGAAAAGGTCTCGGCGCGGCTGAAAAAGTCGGGCATT
GCCGGGCGCACCGTGGTGCTGAAGCTGAAGACCCAGGATTTCAAGCTGCGCACGCGAAACCGCCAGCTCGGCGATCCGAC
AAGGCTCGCGGACCGTATCTTTCAGGCCGGGGTCGAGCTTCTACGCAAGGAAACGGACGGAACGAAATTTCGATTGCTCG
GCATCGGCGTCAGCGACCTCTCCGACGACGACAAGGCCGACCCGCCGGATCTGGTCGACGTCCAGTCGCGCAAGCGCGCC
ATGGCCGAAGGCGCCATCGATGCGCTGCGCGACAAGTTCGGCCGCAAGGCGGTGGAAACCGGCTATACGTTCGGCAGGGG
CCGCGACGCCCATCCGCCGGAGCCGCTGGAAGACTAA

Upstream 100 bases:

>100_bases
GCGGTACTATGGTCGTGCTCATACGGTTCTCCCCAGGCCAAGCTTGTCGCTGACCCTGCACTGTCGTACCATTGCCTCTG
TTCTCTTTATGTTCGCAGTG

Downstream 100 bases:

>100_bases
GAACACCGGATGTGTTGAGATTCAGGTCAGGCCGTCAGGTGCGCGACAGATCGATCCTGCTCATCACCACGTTCTTGCCG
GTTTTCGGATCGGTATCGGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MAAPVNNPDHGFCRDCLTFQRSETRRCERCGSPRLARHPELYRLHLAHIDCDAFYAAIEKRDNPALKDKPLIIGGGKRGV
VSTACYIARIRGVRSAMPMFKALEACPEAVVIPPNMEKYVRVGREVRAMMQTLTPLVEPLSIDEAFLDFAGTERLHGQPP
AVVLARFALAVEKEIGITVSAGLSYCKFLAKIASDFRKPRGFSVIGEAEAVGFLATKPVTMIWGVGKAFNATLERDGIRT
IGQLQTMERGDLMRRYGVMGDRLYRLSRGEDVRRVDPDQDAKSVSAETTFDTDIASLDELVSVLRGLSEKVSARLKKSGI
AGRTVVLKLKTQDFKLRTRNRQLGDPTRLADRIFQAGVELLRKETDGTKFRLLGIGVSDLSDDDKADPPDLVDVQSRKRA
MAEGAIDALRDKFGRKAVETGYTFGRGRDAHPPEPLED

Sequences:

>Translated_438_residues
MAAPVNNPDHGFCRDCLTFQRSETRRCERCGSPRLARHPELYRLHLAHIDCDAFYAAIEKRDNPALKDKPLIIGGGKRGV
VSTACYIARIRGVRSAMPMFKALEACPEAVVIPPNMEKYVRVGREVRAMMQTLTPLVEPLSIDEAFLDFAGTERLHGQPP
AVVLARFALAVEKEIGITVSAGLSYCKFLAKIASDFRKPRGFSVIGEAEAVGFLATKPVTMIWGVGKAFNATLERDGIRT
IGQLQTMERGDLMRRYGVMGDRLYRLSRGEDVRRVDPDQDAKSVSAETTFDTDIASLDELVSVLRGLSEKVSARLKKSGI
AGRTVVLKLKTQDFKLRTRNRQLGDPTRLADRIFQAGVELLRKETDGTKFRLLGIGVSDLSDDDKADPPDLVDVQSRKRA
MAEGAIDALRDKFGRKAVETGYTFGRGRDAHPPEPLED
>Mature_437_residues
AAPVNNPDHGFCRDCLTFQRSETRRCERCGSPRLARHPELYRLHLAHIDCDAFYAAIEKRDNPALKDKPLIIGGGKRGVV
STACYIARIRGVRSAMPMFKALEACPEAVVIPPNMEKYVRVGREVRAMMQTLTPLVEPLSIDEAFLDFAGTERLHGQPPA
VVLARFALAVEKEIGITVSAGLSYCKFLAKIASDFRKPRGFSVIGEAEAVGFLATKPVTMIWGVGKAFNATLERDGIRTI
GQLQTMERGDLMRRYGVMGDRLYRLSRGEDVRRVDPDQDAKSVSAETTFDTDIASLDELVSVLRGLSEKVSARLKKSGIA
GRTVVLKLKTQDFKLRTRNRQLGDPTRLADRIFQAGVELLRKETDGTKFRLLGIGVSDLSDDDKADPPDLVDVQSRKRAM
AEGAIDALRDKFGRKAVETGYTFGRGRDAHPPEPLED

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7705344, Length=105, Percent_Identity=46.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI84043967, Length=342, Percent_Identity=26.6081871345029, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI7706681, Length=343, Percent_Identity=26.530612244898, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI154350220, Length=305, Percent_Identity=26.5573770491803, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=39.1304347826087, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1787432, Length=376, Percent_Identity=24.468085106383, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=416, Percent_Identity=30.5288461538462, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193205702, Length=257, Percent_Identity=31.9066147859922, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17537959, Length=294, Percent_Identity=22.7891156462585, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19923006, Length=343, Percent_Identity=23.9067055393586, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355641, Length=285, Percent_Identity=25.6140350877193, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644984, Length=285, Percent_Identity=25.6140350877193, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24668444, Length=164, Percent_Identity=32.3170731707317, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO41_RHILO (Q98LV1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102576.1
- ProteinModelPortal:   Q98LV1
- SMR:   Q98LV1
- GeneID:   1225239
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr0866
- NMPDR:   fig|266835.1.peg.681
- HOGENOM:   HBG734504
- OMA:   ACYIARI
- ProtClustDB:   PRK02794
- BRENDA:   2.7.7.7
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 48490; Mature: 48359

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 144-144

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPVNNPDHGFCRDCLTFQRSETRRCERCGSPRLARHPELYRLHLAHIDCDAFYAAIEK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHCCHHHHHHHHHH
RDNPALKDKPLIIGGGKRGVVSTACYIARIRGVRSAMPMFKALEACPEAVVIPPNMEKYV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHH
RVGREVRAMMQTLTPLVEPLSIDEAFLDFAGTERLHGQPPAVVLARFALAVEKEIGITVS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEHH
AGLSYCKFLAKIASDFRKPRGFSVIGEAEAVGFLATKPVTMIWGVGKAFNATLERDGIRT
HHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHEEEECCHHHHHHHHHCCHHH
IGQLQTMERGDLMRRYGVMGDRLYRLSRGEDVRRVDPDQDAKSVSAETTFDTDIASLDEL
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHH
VSVLRGLSEKVSARLKKSGIAGRTVVLKLKTQDFKLRTRNRQLGDPTRLADRIFQAGVEL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LRKETDGTKFRLLGIGVSDLSDDDKADPPDLVDVQSRKRAMAEGAIDALRDKFGRKAVET
HHHCCCCCEEEEEEECHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHC
GYTFGRGRDAHPPEPLED
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAPVNNPDHGFCRDCLTFQRSETRRCERCGSPRLARHPELYRLHLAHIDCDAFYAAIEK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHCCHHHHHHHHHH
RDNPALKDKPLIIGGGKRGVVSTACYIARIRGVRSAMPMFKALEACPEAVVIPPNMEKYV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHH
RVGREVRAMMQTLTPLVEPLSIDEAFLDFAGTERLHGQPPAVVLARFALAVEKEIGITVS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEHH
AGLSYCKFLAKIASDFRKPRGFSVIGEAEAVGFLATKPVTMIWGVGKAFNATLERDGIRT
HHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCHHEEEECCHHHHHHHHHCCHHH
IGQLQTMERGDLMRRYGVMGDRLYRLSRGEDVRRVDPDQDAKSVSAETTFDTDIASLDEL
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHH
VSVLRGLSEKVSARLKKSGIAGRTVVLKLKTQDFKLRTRNRQLGDPTRLADRIFQAGVEL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LRKETDGTKFRLLGIGVSDLSDDDKADPPDLVDVQSRKRAMAEGAIDALRDKFGRKAVET
HHHCCCCCEEEEEEECHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHC
GYTFGRGRDAHPPEPLED
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968