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The map label for this gene is ccdA [H]

Identifier: 13470987

GI number: 13470987

Start: 667211

End: 667957

Strand: Reverse

Name: ccdA [H]

Synonym: mll0838

Alternate gene names: 13470987

Gene position: 667957-667211 (Counterclockwise)

Preceding gene: 13470995

Following gene: 13470986

Centisome position: 9.49

GC content: 65.19

Gene sequence:

>747_bases
ATGGCATTGGACATCGGCTATGTCAGCGCCGTCGGGGCGGGAGCCATCTCGTTCCTGTCGCCTTGCGTGCTGCCGCTGGT
GCCGCCCTATCTCTGCTACATGGCAGGCGTTTCGGTCGACGACTTCCGTGGCGATGCGGGCGTCACAGCCCGCGAAGGCA
CGCGCGGGGCACTGCTCTATTCTTCCATCGCCTTCGTGCTCGGCTTTTCGACCGTGTTCGTCGCGCTCGGCGCCGGCGCC
TCGACAATCGGCCGGCTCTTGCGCGTCTGGCAGGAGCCGCTGGCGATGGGCGCCGGCGTGCTGATCATCCTGATGGGCCT
GAATTTCCTCGGCATATTGCGCATTCCGCTGCTGTCGCGCGAGGCTCGTTTCCAGTCGCAAGGCAAGCCGGCAAATGCTA
TCGCCGCGTATATCATGGGGCTCGCCTTCGCCTTCGGCTGGACGCCCTGCATCGGCCCGGTGCTGGGGCCGATCCTGACG
CTGGCCGGCGGGCGCGAGACGGTGGGCGAGGGTGCGCTGCTGCTCGCCGCTTATTCGCTCGGACTTGGAATACCGTTTCT
GATCGCCGCCGTGTTTTCTGGCGCCTTCATGCGCTTCCTCGGCAAATTCCGCGTCCATCTCGGCCGCGTTGAAAAGGCGA
TCGGCGCTCTGCTGGTAGTCGCCGGCGTGTTTTTCCTAACCGGCGGCGTGCAGACCGTGTCCTACTGGCTGCTGGAGAAT
TTTCCGGTGCTGGGTCGGCTGGGGTAA

Upstream 100 bases:

>100_bases
CGTCCCCCATGTCCGTATGCGGCTGACTTTCCACACAATGGTGATTGGCAGACAGGCCTGGCCGTCGCTATATCCGCCGG
GGAGCAGTTGGAGTTTTGGA

Downstream 100 bases:

>100_bases
GTTCCCCCCGCTTTTGCGGTAAAGGATCTGGCAGTGGACCTGCTGATTAAAAGTCACTTGCTCGACTATCTCACCGGAAT
TTAACCGCATTGGTGCAGCA

Product: c-type cytochrome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MALDIGYVSAVGAGAISFLSPCVLPLVPPYLCYMAGVSVDDFRGDAGVTAREGTRGALLYSSIAFVLGFSTVFVALGAGA
STIGRLLRVWQEPLAMGAGVLIILMGLNFLGILRIPLLSREARFQSQGKPANAIAAYIMGLAFAFGWTPCIGPVLGPILT
LAGGRETVGEGALLLAAYSLGLGIPFLIAAVFSGAFMRFLGKFRVHLGRVEKAIGALLVVAGVFFLTGGVQTVSYWLLEN
FPVLGRLG

Sequences:

>Translated_248_residues
MALDIGYVSAVGAGAISFLSPCVLPLVPPYLCYMAGVSVDDFRGDAGVTAREGTRGALLYSSIAFVLGFSTVFVALGAGA
STIGRLLRVWQEPLAMGAGVLIILMGLNFLGILRIPLLSREARFQSQGKPANAIAAYIMGLAFAFGWTPCIGPVLGPILT
LAGGRETVGEGALLLAAYSLGLGIPFLIAAVFSGAFMRFLGKFRVHLGRVEKAIGALLVVAGVFFLTGGVQTVSYWLLEN
FPVLGRLG
>Mature_247_residues
ALDIGYVSAVGAGAISFLSPCVLPLVPPYLCYMAGVSVDDFRGDAGVTAREGTRGALLYSSIAFVLGFSTVFVALGAGAS
TIGRLLRVWQEPLAMGAGVLIILMGLNFLGILRIPLLSREARFQSQGKPANAIAAYIMGLAFAFGWTPCIGPVLGPILTL
AGGRETVGEGALLLAAYSLGLGIPFLIAAVFSGAFMRFLGKFRVHLGRVEKAIGALLVVAGVFFLTGGVQTVSYWLLENF
PVLGRLG

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 25831; Mature: 25700

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCC
>Mature Secondary Structure 
ALDIGYVSAVGAGAISFLSPCVLPLVPPYLCYMAGVSVDDFRGDAGVTAREGTRGALLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHH
SSIAFVLGFSTVFVALGAGASTIGRLLRVWQEPLAMGAGVLIILMGLNFLGILRIPLLSR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARFQSQGKPANAIAAYIMGLAFAFGWTPCIGPVLGPILTLAGGRETVGEGALLLAAYSL
HHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHH
GLGIPFLIAAVFSGAFMRFLGKFRVHLGRVEKAIGALLVVAGVFFLTGGVQTVSYWLLEN
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
FPVLGRLG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]