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The map label for this gene is folB [H]

Identifier: 13470948

GI number: 13470948

Start: 617657

End: 618016

Strand: Reverse

Name: folB [H]

Synonym: mll0787

Alternate gene names: 13470948

Gene position: 618016-617657 (Counterclockwise)

Preceding gene: 13470949

Following gene: 13470947

Centisome position: 8.78

GC content: 60.56

Gene sequence:

>360_bases
ATGTATGTCATCCGCCTGAAGAACTGCGCCTTCTTTGCCCGGCATGGCGTCCTCGACGAAGAGGAGGCGCTCGGCCAGCG
TTTCTATGTCGATGCAGTGTTGTCGGTCGAACCCGGGCGCGCGCTTGTCGACGACGCGATCGAGGAAACCGTCAACTACG
GCATTGCCTTCACGGTGATCGAAAAGATCATCACCGGCGAACGGCGCTTCCTGATCGAGGCCCTCGCCATGGAAGTGGCA
AAGGCGCTGACGGAGCGGTTTCCCCAGATCAGGAGGGCCGAAATCACCGTGCGCAAGCCAAACGCACCGGTGCCTGGCGT
GCTCGATTATGTCGAGGTGACCGTTGTCTGGCCCGAGTAA

Upstream 100 bases:

>100_bases
GCATCTGTTTCGCGTCCACGATGTCGCAATCAACGTGGACGCTCTGGCCATGGCGGATGCTATGCTGGCGCGTGAAACTG
CCGCATCGGAACGCTGAGCC

Downstream 100 bases:

>100_bases
CACCGTCTACCTCAGCCTCGGCGGCAATCTGGGCGATCCGGCGGCCTCGATGGCGGCGGCGCTGCGCATTCTCGATGCCG
ATACGGATACGCGCGTCACC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MYVIRLKNCAFFARHGVLDEEEALGQRFYVDAVLSVEPGRALVDDAIEETVNYGIAFTVIEKIITGERRFLIEALAMEVA
KALTERFPQIRRAEITVRKPNAPVPGVLDYVEVTVVWPE

Sequences:

>Translated_119_residues
MYVIRLKNCAFFARHGVLDEEEALGQRFYVDAVLSVEPGRALVDDAIEETVNYGIAFTVIEKIITGERRFLIEALAMEVA
KALTERFPQIRRAEITVRKPNAPVPGVLDYVEVTVVWPE
>Mature_119_residues
MYVIRLKNCAFFARHGVLDEEEALGQRFYVDAVLSVEPGRALVDDAIEETVNYGIAFTVIEKIITGERRFLIEALAMEVA
KALTERFPQIRRAEITVRKPNAPVPGVLDYVEVTVVWPE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13465; Mature: 13465

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVIRLKNCAFFARHGVLDEEEALGQRFYVDAVLSVEPGRALVDDAIEETVNYGIAFTVI
CEEEEECCHHHHHHCCCCCCHHHHCHHEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHH
EKIITGERRFLIEALAMEVAKALTERFPQIRRAEITVRKPNAPVPGVLDYVEVTVVWPE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MYVIRLKNCAFFARHGVLDEEEALGQRFYVDAVLSVEPGRALVDDAIEETVNYGIAFTVI
CEEEEECCHHHHHHCCCCCCHHHHCHHEEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHH
EKIITGERRFLIEALAMEVAKALTERFPQIRRAEITVRKPNAPVPGVLDYVEVTVVWPE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9168622 [H]