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The map label for this gene is ycaN [H]

Identifier: 13470844

GI number: 13470844

Start: 511492

End: 512427

Strand: Direct

Name: ycaN [H]

Synonym: mlr0648

Alternate gene names: 13470844

Gene position: 511492-512427 (Clockwise)

Preceding gene: 13470829

Following gene: 13470850

Centisome position: 7.27

GC content: 64.85

Gene sequence:

>936_bases
ATGGATCGCGATCTCCTCACGCATCTGCCTGTCATTGTAGCCGTTGCCCGGCGCGGCGGCTTCGCGCTTGCGGCAGCTGA
ACTCGGCATGAGCCCGTCAGCGGTCAGCCATGCCGTGCGGCTGGTCGAGGAGCGCATAGGCCAGCCTTTGTTCGCGCGTA
CGACGCGCAGTGTTTCGCTGACCGAGGCCGGCAAGGCGCTGGTGGAGACCGCGGCCCCTGCCCTTCAGGATATCGGCGAG
CGGATCGATCAAATCCGCAGCGTCAAGGGCAGGCCGTCCGGCCTGCTCAGGATCAACGCCTCCACCATCGCGATTCCATT
GGCGGTGACGCCTGTGGTCGCGGCGATGGCCGAGCGCTATCCGGACGTTACGGTGGAGATTTTCGCCGATCAGGGACTGG
TCGACATCGTCGGCGAAGGTTTTGACGCTGGCATCCGGCTGGGCGAGATGATCGCGCAGGACATGGTGGCCGTGCGGCTC
ACGCCTCCGTTCAGAACCATCATCGTCGCCTCTCCTGCCTATATCGGACGCCACGGCCGTCCGCGCAGCGTGGCCGATCT
CGCCAACCACAATTGCATCGGCTACCGGCTCATCCGCTCCGGTGCCCTCTATCGCTGGGACCTGGCCGAAGACGGCAAGG
ATGTCATCATGGAGACCGGCGGTACGGCCATCGTCACGGATTCGCTTGCCGCGATCGACCTGGCGCTTGCCGGAGTGGGC
CTTGCCTATATGTTCGAGCCGCTGGCGCGCGCCGATCTTGCGGCCGGCCGCCTGGTGCAGGTTCTGCCGCAATCGGCAAT
CGAGGAACCTGGCCTTTTCCTCTACTTCCCGCGCCGGGCGGCGATGGCGCCGAAACTGCGGGCCTTTATCGACACCGCAC
AAGAAATCGGCCGGACATCCCTGCGGACATCCGGCCGAAAAACGCTTTCGGAATAA

Upstream 100 bases:

>100_bases
TTGGTGCCATCAGCCAATCGCTGTTGGGGACAATGTGGACCACTGTCTCGGCATCGATAAGATTGCATTGTCTGCAAAGA
CCATGCGATATCGTTCATGA

Downstream 100 bases:

>100_bases
AGCGGTAGGAAGTTTACTTCTTGACCGCCGCAGCGACTTCCGCCGCGAAATCGGTCTCTTCCTTCTCGATGCCTTCGCCG
AGCGCGAAGCGCAGATAGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MDRDLLTHLPVIVAVARRGGFALAAAELGMSPSAVSHAVRLVEERIGQPLFARTTRSVSLTEAGKALVETAAPALQDIGE
RIDQIRSVKGRPSGLLRINASTIAIPLAVTPVVAAMAERYPDVTVEIFADQGLVDIVGEGFDAGIRLGEMIAQDMVAVRL
TPPFRTIIVASPAYIGRHGRPRSVADLANHNCIGYRLIRSGALYRWDLAEDGKDVIMETGGTAIVTDSLAAIDLALAGVG
LAYMFEPLARADLAAGRLVQVLPQSAIEEPGLFLYFPRRAAMAPKLRAFIDTAQEIGRTSLRTSGRKTLSE

Sequences:

>Translated_311_residues
MDRDLLTHLPVIVAVARRGGFALAAAELGMSPSAVSHAVRLVEERIGQPLFARTTRSVSLTEAGKALVETAAPALQDIGE
RIDQIRSVKGRPSGLLRINASTIAIPLAVTPVVAAMAERYPDVTVEIFADQGLVDIVGEGFDAGIRLGEMIAQDMVAVRL
TPPFRTIIVASPAYIGRHGRPRSVADLANHNCIGYRLIRSGALYRWDLAEDGKDVIMETGGTAIVTDSLAAIDLALAGVG
LAYMFEPLARADLAAGRLVQVLPQSAIEEPGLFLYFPRRAAMAPKLRAFIDTAQEIGRTSLRTSGRKTLSE
>Mature_311_residues
MDRDLLTHLPVIVAVARRGGFALAAAELGMSPSAVSHAVRLVEERIGQPLFARTTRSVSLTEAGKALVETAAPALQDIGE
RIDQIRSVKGRPSGLLRINASTIAIPLAVTPVVAAMAERYPDVTVEIFADQGLVDIVGEGFDAGIRLGEMIAQDMVAVRL
TPPFRTIIVASPAYIGRHGRPRSVADLANHNCIGYRLIRSGALYRWDLAEDGKDVIMETGGTAIVTDSLAAIDLALAGVG
LAYMFEPLARADLAAGRLVQVLPQSAIEEPGLFLYFPRRAAMAPKLRAFIDTAQEIGRTSLRTSGRKTLSE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=38.0622837370242, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1787589, Length=298, Percent_Identity=36.241610738255, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=32.0945945945946, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=34.375, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789440, Length=262, Percent_Identity=29.3893129770992, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789639, Length=310, Percent_Identity=24.5161290322581, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=27.0833333333333, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788706, Length=301, Percent_Identity=25.9136212624585, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786448, Length=283, Percent_Identity=26.5017667844523, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=29.3103448275862, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787949, Length=134, Percent_Identity=32.089552238806, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=291, Percent_Identity=27.1477663230241, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=25.7627118644068, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786713, Length=151, Percent_Identity=31.7880794701987, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=118, Percent_Identity=33.8983050847458, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33230; Mature: 33230

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRDLLTHLPVIVAVARRGGFALAAAELGMSPSAVSHAVRLVEERIGQPLFARTTRSVSL
CCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEH
TEAGKALVETAAPALQDIGERIDQIRSVKGRPSGLLRINASTIAIPLAVTPVVAAMAERY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHC
PDVTVEIFADQGLVDIVGEGFDAGIRLGEMIAQDMVAVRLTPPFRTIIVASPAYIGRHGR
CCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCHHHCCCCC
PRSVADLANHNCIGYRLIRSGALYRWDLAEDGKDVIMETGGTAIVTDSLAAIDLALAGVG
CCHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEEECHHHHHHHHHHHHH
LAYMFEPLARADLAAGRLVQVLPQSAIEEPGLFLYFPRRAAMAPKLRAFIDTAQEIGRTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LRTSGRKTLSE
HHHCCHHHCCC
>Mature Secondary Structure
MDRDLLTHLPVIVAVARRGGFALAAAELGMSPSAVSHAVRLVEERIGQPLFARTTRSVSL
CCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEH
TEAGKALVETAAPALQDIGERIDQIRSVKGRPSGLLRINASTIAIPLAVTPVVAAMAERY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEHHHHHHHHHHHHHHC
PDVTVEIFADQGLVDIVGEGFDAGIRLGEMIAQDMVAVRLTPPFRTIIVASPAYIGRHGR
CCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCHHHCCCCC
PRSVADLANHNCIGYRLIRSGALYRWDLAEDGKDVIMETGGTAIVTDSLAAIDLALAGVG
CCHHHHHHCCCCHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEEECHHHHHHHHHHHHH
LAYMFEPLARADLAAGRLVQVLPQSAIEEPGLFLYFPRRAAMAPKLRAFIDTAQEIGRTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LRTSGRKTLSE
HHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]